Gene/Proteome Database (LMPD)
Proteins
protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha | |
---|---|
Refseq ID | NP_032059 |
Protein GI | 6679821 |
UniProt ID | Q541Z2 |
mRNA ID | NM_008033 |
Length | 377 |
RefSeq Status | PROVISIONAL |
MAATEGVGESAAGGEPGQPEQPPPPPPPPPAQQPQEEEMAAEAGEAAASPMDDGFLSLDSPTYVLYRDRAEWADIDPVPQNDGPNPVVQIIYSEKFRDVYDYFRAVLQRDERSERAFKLTRDAIELNAANYTVWHFRRVLLRSLQKDLQEEMNYITAIIEEQPKNYQVWHHRRVLVEWLKDPSQELEFIADILSQDAKNYHAWQHRQWVIQEFRLWDNELQYVDQLLKEDVRNNSVWNQRHFVISNTTGYSDRAVLEREVQYTLEMIKLVPHNESAWNYLKGILQDRGLSRYPNLLNQLLDLQPSHSSPYLIAFLVDVYEDMLENQCDNKEDILNKALELCEILAKEKDTIRKEYWRYIGRSLQSKHCRESDIPASV |
Gene Information
Entrez Gene ID
Gene Name
farnesyltransferase, CAAX box, alpha
Gene Symbol
Species
Mus musculus
Gene Ontology (GO Annotations)
GO ID | Source | Type | Description |
---|---|---|---|
GO:0005953 | IEA:Ensembl | C | CAAX-protein geranylgeranyltransferase complex |
GO:0005875 | IEA:Ensembl | C | microtubule associated complex |
GO:0005965 | IEA:Ensembl | C | protein farnesyltransferase complex |
GO:0030548 | IMP:MGI | F | acetylcholine receptor regulator activity |
GO:0004660 | IEA:Ensembl | F | protein farnesyltransferase activity |
GO:0004661 | IEA:Ensembl | F | protein geranylgeranyltransferase activity |
GO:0007528 | IMP:UniProtKB | P | neuromuscular junction development |
GO:0045213 | IMP:MGI | P | neurotransmitter receptor metabolic process |
GO:0090045 | IEA:Ensembl | P | positive regulation of deacetylase activity |
GO:0090044 | IEA:Ensembl | P | positive regulation of tubulin deacetylation |
GO:0018343 | IEA:Ensembl | P | protein farnesylation |
GO:0018344 | IEA:Ensembl | P | protein geranylgeranylation |
GO:0010469 | IMP:GOC | P | regulation of receptor activity |
GO:0071340 | IDA:UniProtKB | P | skeletal muscle acetylcholine-gated channel clustering |
Domain Information
InterPro Annotations
Accession | Description |
---|---|
IPR002088 | Protein prenyltransferase, alpha subunit |
UniProt Annotations
Entry Information
Gene Name
farnesyltransferase, CAAX box, alpha
Protein Entry
FNTA_MOUSE
UniProt ID
Species
Mouse
Identical and Related Proteins
Unique RefSeq proteins for LMP003018 (as displayed in Record Overview)
Protein GI | Database | Accession | Length | Protein Name |
---|---|---|---|---|
6679821 | RefSeq | NP_032059 | 377 | protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha |
Identical Sequences to LMP003018 proteins
Reference | Database | Accession | Length | Protein Name |
---|---|---|---|---|
GI:6679821 | DBBJ | BAA08578.1 | 377 | farnesyltransferase alpha subunit [Mus musculus] |
GI:6679821 | DBBJ | BAB27154.1 | 377 | unnamed protein product [Mus musculus] |
GI:6679821 | DBBJ | BAC41179.1 | 377 | unnamed protein product [Mus musculus] |
GI:6679821 | DBBJ | BAE31843.1 | 377 | unnamed protein product [Mus musculus] |
GI:6679821 | SwissProt | Q61239.1 | 377 | RecName: Full=Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha; AltName: Full=CAAX farnesyltransferase subunit alpha; AltName: Full=FTase-alpha; AltName: Full=Ras proteins prenyltransferase subunit alpha; AltName: Full=Type I protein geranyl-geranyltransferase subunit alpha; Short=GGTase-I-alpha [Mus musculus] |
Related Sequences to LMP003018 proteins
Reference | Database | Accession | Length | Protein Name |
---|---|---|---|---|
GI:6679821 | GenBank | AAH12711.1 | 377 | Farnesyltransferase, CAAX box, alpha [Mus musculus] |
GI:6679821 | PDB | 1O1R | 380 | Chain A, Structure Of Fpt Bound To Ggpp |
GI:6679821 | PDB | 1O1S | 380 | Chain A, Structure Of Fpt Bound To Isoprenoid Analog 3b |
GI:6679821 | PDB | 1O1T | 380 | Chain A, Structure Of Fpt Bound To The Cvim-Fpp Product |
GI:6679821 | PDB | 3KSL | 377 | Chain A, Structure Of Fpt Bound To Datfp-Dh-Gpp |
GI:6679821 | PDB | 3KSQ | 377 | Chain A, Discovery Of C-Imidazole Azaheptapyridine Fpt Inhibitors |