Gene/Proteome Database (LMPD)

LMPD ID
LMP003018
Gene ID
14272
Species
Mus musculus (Mouse)
Gene Name
farnesyltransferase, CAAX box, alpha
Gene Symbol
Fnta
Synonyms
FTA
Chromosome
8
Map Location
8 A2|8 14.27 cM

Proteins

protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha
Refseq ID NP_032059
Protein GI 6679821
UniProt ID Q541Z2
mRNA ID NM_008033
Length 377
RefSeq Status PROVISIONAL
MAATEGVGESAAGGEPGQPEQPPPPPPPPPAQQPQEEEMAAEAGEAAASPMDDGFLSLDSPTYVLYRDRAEWADIDPVPQNDGPNPVVQIIYSEKFRDVYDYFRAVLQRDERSERAFKLTRDAIELNAANYTVWHFRRVLLRSLQKDLQEEMNYITAIIEEQPKNYQVWHHRRVLVEWLKDPSQELEFIADILSQDAKNYHAWQHRQWVIQEFRLWDNELQYVDQLLKEDVRNNSVWNQRHFVISNTTGYSDRAVLEREVQYTLEMIKLVPHNESAWNYLKGILQDRGLSRYPNLLNQLLDLQPSHSSPYLIAFLVDVYEDMLENQCDNKEDILNKALELCEILAKEKDTIRKEYWRYIGRSLQSKHCRESDIPASV

Gene Information

Entrez Gene ID
14272
Gene Name
farnesyltransferase, CAAX box, alpha
Gene Symbol
Fnta
Species
Mus musculus

Gene Ontology (GO Annotations)

GO ID Source Type Description
GO:0005953 IEA:Ensembl C CAAX-protein geranylgeranyltransferase complex
GO:0005875 IEA:Ensembl C microtubule associated complex
GO:0005965 IEA:Ensembl C protein farnesyltransferase complex
GO:0030548 IMP:MGI F acetylcholine receptor regulator activity
GO:0004660 IEA:Ensembl F protein farnesyltransferase activity
GO:0004661 IEA:Ensembl F protein geranylgeranyltransferase activity
GO:0007528 IMP:UniProtKB P neuromuscular junction development
GO:0045213 IMP:MGI P neurotransmitter receptor metabolic process
GO:0090045 IEA:Ensembl P positive regulation of deacetylase activity
GO:0090044 IEA:Ensembl P positive regulation of tubulin deacetylation
GO:0018343 IEA:Ensembl P protein farnesylation
GO:0018344 IEA:Ensembl P protein geranylgeranylation
GO:0010469 IMP:GOC P regulation of receptor activity
GO:0071340 IDA:UniProtKB P skeletal muscle acetylcholine-gated channel clustering

Domain Information

InterPro Annotations

Accession Description
IPR002088 Protein prenyltransferase, alpha subunit

UniProt Annotations

Entry Information

Gene Name
farnesyltransferase, CAAX box, alpha
Protein Entry
FNTA_MOUSE
UniProt ID
Q541Z2
Species
Mouse

Identical and Related Proteins

Unique RefSeq proteins for LMP003018 (as displayed in Record Overview)

Protein GI Database Accession Length Protein Name
6679821 RefSeq NP_032059 377 protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha

Identical Sequences to LMP003018 proteins

Reference Database Accession Length Protein Name
GI:6679821 DBBJ BAA08578.1 377 farnesyltransferase alpha subunit [Mus musculus]
GI:6679821 DBBJ BAB27154.1 377 unnamed protein product [Mus musculus]
GI:6679821 DBBJ BAC41179.1 377 unnamed protein product [Mus musculus]
GI:6679821 DBBJ BAE31843.1 377 unnamed protein product [Mus musculus]
GI:6679821 SwissProt Q61239.1 377 RecName: Full=Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha; AltName: Full=CAAX farnesyltransferase subunit alpha; AltName: Full=FTase-alpha; AltName: Full=Ras proteins prenyltransferase subunit alpha; AltName: Full=Type I protein geranyl-geranyltransferase subunit alpha; Short=GGTase-I-alpha [Mus musculus]

Related Sequences to LMP003018 proteins

Reference Database Accession Length Protein Name
GI:6679821 GenBank AAH12711.1 377 Farnesyltransferase, CAAX box, alpha [Mus musculus]
GI:6679821 PDB 1O1R 380 Chain A, Structure Of Fpt Bound To Ggpp
GI:6679821 PDB 1O1S 380 Chain A, Structure Of Fpt Bound To Isoprenoid Analog 3b
GI:6679821 PDB 1O1T 380 Chain A, Structure Of Fpt Bound To The Cvim-Fpp Product
GI:6679821 PDB 3KSL 377 Chain A, Structure Of Fpt Bound To Datfp-Dh-Gpp
GI:6679821 PDB 3KSQ 377 Chain A, Discovery Of C-Imidazole Azaheptapyridine Fpt Inhibitors