Gene/Proteome Database (LMPD)

LMPD ID
LMP003146
Gene ID
13850
Species
Mus musculus (Mouse)
Gene Name
epoxide hydrolase 2, cytoplasmic
Gene Symbol
Ephx2
Synonyms
CEH; Eph2; SEH; sEP
Chromosome
14
Map Location
14 D|14 34.36 cM

Proteins

bifunctional epoxide hydrolase 2 isoform a
Refseq ID NP_031966
Protein GI 31982393
UniProt ID Q3UQ71
mRNA ID NM_007940
Length 554
RefSeq Status VALIDATED
MALRVAAFDLDGVLALPSIAGAFRRSEEALALPRDFLLGAYQTEFPEGPTEQLMKGKITFSQWVPLMDESYRKSSKACGANLPENFSISQIFSQAMAARSINRPMLQAAIALKKKGFTTCIVTNNWLDDGDKRDSLAQMMCELSQHFDFLIESCQVGMIKPEPQIYNFLLDTLKAKPNEVVFLDDFGSNLKPARDMGMVTILVHNTASALRELEKVTGTQFPEAPLPVPCNPNDVSHGYVTVKPGIRLHFVEMGSGPALCLCHGFPESWFSWRYQIPALAQAGFRVLAIDMKGYGDSSSPPEIEEYAMELLCKEMVTFLDKLGIPQAVFIGHDWAGVMVWNMALFYPERVRAVASLNTPFMPPDPDVSPMKVIRSIPVFNYQLYFQEPGVAEAELEKNMSRTFKSFFRASDETGFIAVHKATEIGGILVNTPEDPNLSKITTEEEIEFYIQQFKKTGFRGPLNWYRNTERNWKWSCKGLGRKILVPALMVTAEKDIVLRPEMSKNMEKWIPFLKRGHIEDCGHWTQIEKPTEVNQILIKWLQTEVQNPSVTSKI
sig_peptide: 1..19 inference: COORDINATES: ab initio prediction:SignalP:4.0 calculated_mol_wt: 2094 peptide sequence: MRFAAMAAFSVFFVSKGLL
bifunctional epoxide hydrolase 2 isoform c precursor
Refseq ID NP_001258332
Protein GI 406647876
UniProt ID P34914
mRNA ID NM_001271403
Length 536
RefSeq Status VALIDATED
MRFAAMAAFSVFFVSKGLLMNSNIWCVGQEGPSQEDTDTIHTSEWVPLMDESYRKSSKACGANLPENFSISQIFSQAMAARSINRPMLQAAIALKKKGFTTCIVTNNWLDDGDKRDSLAQMMCELSQHFDFLIESCQVGMIKPEPQIYNFLLDTLKAKPNEVVFLDDFGSNLKPARDMGMVTILVHNTASALRELEKVTGTQFPEAPLPVPCNPNDVSHGYVTVKPGIRLHFVEMGSGPALCLCHGFPESWFSWRYQIPALAQAGFRVLAIDMKGYGDSSSPPEIEEYAMELLCKEMVTFLDKLGIPQAVFIGHDWAGVMVWNMALFYPERVRAVASLNTPFMPPDPDVSPMKVIRSIPVFNYQLYFQEPGVAEAELEKNMSRTFKSFFRASDETGFIAVHKATEIGGILVNTPEDPNLSKITTEEEIEFYIQQFKKTGFRGPLNWYRNTERNWKWSCKGLGRKILVPALMVTAEKDIVLRPEMSKNMEKWIPFLKRGHIEDCGHWTQIEKPTEVNQILIKWLQTEVQNPSVTSKI
bifunctional epoxide hydrolase 2 isoform d
Refseq ID NP_001258350
Protein GI 406647884
UniProt ID A8JYK8
mRNA ID NM_001271421
Length 488
RefSeq Status VALIDATED
MDESYRKSSKACGANLPENFSISQIFSQAMAARSINRPMLQAAIALKKKGFTTCIVTNNWLDDGDKRDSLAQMMCELSQHFDFLIESCQVGMIKPEPQIYNFLLDTLKAKPNEVVFLDDFGSNLKPARDMGMVTILVHNTASALRELEKVTGTQFPEAPLPVPCNPNDVSHGYVTVKPGIRLHFVEMGSGPALCLCHGFPESWFSWRYQIPALAQAGFRVLAIDMKGYGDSSSPPEIEEYAMELLCKEMVTFLDKLGIPQAVFIGHDWAGVMVWNMALFYPERVRAVASLNTPFMPPDPDVSPMKVIRSIPVFNYQLYFQEPGVAEAELEKNMSRTFKSFFRASDETGFIAVHKATEIGGILVNTPEDPNLSKITTEEEIEFYIQQFKKTGFRGPLNWYRNTERNWKWSCKGLGRKILVPALMVTAEKDIVLRPEMSKNMEKWIPFLKRGHIEDCGHWTQIEKPTEVNQILIKWLQTEVQNPSVTSKI

Gene Information

Entrez Gene ID
13850
Gene Name
epoxide hydrolase 2, cytoplasmic
Gene Symbol
Ephx2
Species
Mus musculus

Gene Ontology (GO Annotations)

GO ID Source Type Description
GO:0070062 IEA:Ensembl C extracellular vesicular exosome
GO:0005777 IEA:Ensembl C peroxisome
GO:0004301 IEA:Ensembl F epoxide hydrolase activity
GO:0042577 IEA:Ensembl F lipid phosphatase activity
GO:0000287 IEA:Ensembl F magnesium ion binding
GO:0015643 IEA:Ensembl F toxic substance binding
GO:0042632 IEA:Ensembl P cholesterol homeostasis
GO:0046839 IEA:Ensembl P phospholipid dephosphorylation
GO:0010628 IEA:Ensembl P positive regulation of gene expression
GO:0090181 IEA:Ensembl P regulation of cholesterol metabolic process
GO:0046272 IEA:Ensembl P stilbene catabolic process

Domain Information

InterPro Annotations

Accession Description
IPR029058 Alpha/Beta hydrolase fold
IPR000073 Alpha/beta hydrolase fold-1
IPR000639 Epoxide hydrolase-like
IPR006439 HAD hydrolase, subfamily IA
IPR023214 HAD-like domain

UniProt Annotations

Entry Information

Gene Name
epoxide hydrolase 2, cytoplasmic
Protein Entry
HYES_MOUSE
UniProt ID
Q3UQ71
Species
Mouse

Identical and Related Proteins

Unique RefSeq proteins for LMP003146 (as displayed in Record Overview)

Protein GI Database Accession Length Protein Name
31982393 RefSeq NP_031966 554 bifunctional epoxide hydrolase 2 isoform a
406647876 RefSeq NP_001258332 536 bifunctional epoxide hydrolase 2 isoform c precursor
406647884 RefSeq NP_001258350 488 bifunctional epoxide hydrolase 2 isoform d

Identical Sequences to LMP003146 proteins

Reference Database Accession Length Protein Name
GI:31982393 GenBank AAH15087.1 554 Epoxide hydrolase 2, cytoplasmic [Mus musculus]
GI:406647876 GenBank AAM28238.1 536 ovary-selective epoxide hydrolase [Mus musculus]
GI:31982393 GenBank EDL36005.1 554 epoxide hydrolase 2, cytoplasmic, isoform CRA_a [Mus musculus]
GI:406647884 GenBank ABU95055.1 488 epoxide hydrolase 2C [Mus musculus]
GI:31982393 GenBank ADF11200.1 554 Sequence 3 from patent US 7662910
GI:406647876 GenBank ADF11201.1 536 Sequence 4 from patent US 7662910
GI:31982393 GenBank AGN61909.1 554 Sequence 3 from patent US 8455652
GI:406647876 GenBank AGN61910.1 536 Sequence 4 from patent US 8455652
GI:31982393 GenBank AGU04326.1 554 Sequence 3 from patent US 8476043
GI:406647876 GenBank AGU04327.1 536 Sequence 4 from patent US 8476043
GI:31982393 PDB 1EK2 554 Chain B, Crystal Structure Of Murine Soluble Epoxide Hydrolase Complexed With Cdu Inhibitor

Related Sequences to LMP003146 proteins

Reference Database Accession Length Protein Name
GI:31982393 DBBJ BAE25172.1 554 unnamed protein product [Mus musculus]
GI:31982393 EMBL CAA85471.1 554 Epoxide Hydrolase [Mus musculus]
GI:31982393 EMBL CBW54675.1 274 thioesterase [Streptomyces sp. JS360]
GI:31982393 GenBank AAA75893.1 553 Sequence 4 from patent US 5445956
GI:406647884 GenBank AAH15087.1 554 Epoxide hydrolase 2, cytoplasmic [Mus musculus]
GI:406647876 GenBank AAH15087.1 554 Epoxide hydrolase 2, cytoplasmic [Mus musculus]
GI:406647876 GenBank EDL36005.1 554 epoxide hydrolase 2, cytoplasmic, isoform CRA_a [Mus musculus]
GI:406647884 GenBank EDL36005.1 554 epoxide hydrolase 2, cytoplasmic, isoform CRA_a [Mus musculus]
GI:31982393 GenBank ADF11199.1 554 Sequence 2 from patent US 7662910
GI:406647876 GenBank ADF11200.1 554 Sequence 3 from patent US 7662910
GI:406647884 GenBank ADF11200.1 554 Sequence 3 from patent US 7662910
GI:31982393 GenBank AGN61908.1 554 Sequence 2 from patent US 8455652
GI:406647884 GenBank AGN61909.1 554 Sequence 3 from patent US 8455652
GI:406647876 GenBank AGN61909.1 554 Sequence 3 from patent US 8455652
GI:406647876 PDB 1CQZ 554 Chain A, Crystal Structure Of Murine Soluble Epoxide Hydrolase.
GI:406647884 PDB 1CQZ 554 Chain A, Crystal Structure Of Murine Soluble Epoxide Hydrolase.
GI:406647876 SwissProt P34914.2 554 RecName: Full=Bifunctional epoxide hydrolase 2; Includes: RecName: Full=Cytosolic epoxide hydrolase 2; Short=CEH; AltName: Full=Epoxide hydratase; AltName: Full=Soluble epoxide hydrolase; Short=SEH; Includes: RecName: Full=Lipid-phosphate phosphatase [Mus musculus]
GI:406647884 SwissProt P34914.2 554 RecName: Full=Bifunctional epoxide hydrolase 2; Includes: RecName: Full=Cytosolic epoxide hydrolase 2; Short=CEH; AltName: Full=Epoxide hydratase; AltName: Full=Soluble epoxide hydrolase; Short=SEH; Includes: RecName: Full=Lipid-phosphate phosphatase [Mus musculus]