Gene/Proteome Database (LMPD)

LMPD ID
LMP003478
Gene ID
26879
Species
Mus musculus (Mouse)
Gene Name
UDP-GalNAc:betaGlcNAc beta 1,3-galactosaminyltransferase, polypeptide 1
Gene Symbol
B3galnt1
Synonyms
B3galt3; b3GT3
Alternate Names
UDP-GalNAc:beta-1,3-N-acetylgalactosaminyltransferase 1; Mbrn 1; b3Gal-T3; Brainiac 1; beta3GalT3; beta-3-Gx-T3; beta-1,3-GalNAc-T1; beta-1,3-GalTase 3; globoside synthase; Globoside blood group; beta-1,3-galactosyltransferase 3; UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase III; UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 3; galactosylgalactosylglucosylceramide beta-D-acetyl-galactosaminyltransferase; UDP-N-acetylgalactosamine:globotriaosylceramide beta-1,3-N-acetylgalactosaminyltransferase
Chromosome
3
Map Location
3 E1|3
EC Number
2.4.1.79

Proteins

UDP-GalNAc:beta-1,3-N-acetylgalactosaminyltransferase 1
Refseq ID NP_064410
Protein GI 9910138
UniProt ID Q920V1
mRNA ID NM_020026
Length 331
RefSeq Status VALIDATED
MAPAVLTALPNRMSLRSLKWSLLLLSLLSFLVIWYLSLPHYNVIERVNWMYFYEYEPIYRQDFRFTLREHSNCSHQNPFLVILVTSRPSDVKARQAIRVTWGEKKSWWGYEVLTFFLLGQQAEREDKTLALSLEDEHVLYGDIIRQDFLDTYNNLTLKTIMAFRWVMEFCPNAKYIMKTDTDVFINTGNLVKYLLNLNHSEKFFTGYPLIDNYSYRGFFHKNHISYQEYPFKVFPPYCSGLGYIMSGDLVPRVYEMMSHVKPIKFEDVYVGICLNLLKVDIHIPEDTNLFFLYRIHLDVCQLRRVIAAHGFSSKEIITFWQVMLRNTTCHY

Gene Information

Entrez Gene ID
26879
Gene Name
UDP-GalNAc:betaGlcNAc beta 1,3-galactosaminyltransferase, polypeptide 1
Gene Symbol
B3galnt1
Species
Mus musculus

Gene Ontology (GO Annotations)

GO ID Source Type Description
GO:0005794 IEA:UniProtKB-KW C Golgi apparatus
GO:0016021 IEA:UniProtKB-KW C integral component of membrane
GO:0008499 IDA:MGI F UDP-galactose:beta-N-acetylglucosamine beta-1,3-galactosyltransferase activity
GO:0047273 IEA:UniProtKB-EC F galactosylgalactosylglucosylceramide beta-D-acetylgalactosaminyltransferase activity
GO:0009312 IDA:MGI P oligosaccharide biosynthetic process
GO:0006486 IEA:UniProtKB-UniPathway P protein glycosylation

KEGG Pathway Links

KEGG Pathway ID Description
ko00603 Glycosphingolipid biosynthesis - globo series
mmu00603 Glycosphingolipid biosynthesis - globo series
mmu01100 Metabolic pathways

Domain Information

InterPro Annotations

Accession Description
IPR002659 Glycosyl transferase, family 31

UniProt Annotations

Entry Information

Gene Name
UDP-GalNAc:betaGlcNAc beta 1,3-galactosaminyltransferase, polypeptide 1
Protein Entry
B3GL1_MOUSE
UniProt ID
Q920V1
Species
Mouse

Comments

Comment Type Description
Catalytic Activity UDP-N-acetyl-alpha-D-galactosamine + alpha-D- galactosyl-(1->4)-beta-D-galactosyl-(1->4)-beta-D-glucosyl- (1<->1)-ceramide = UDP + N-acetyl-beta-D-galactosaminyl-(1->3)- alpha-D-galactosyl-(1->4)-beta-D-galactosyl-(1->4)-beta-D- glucosyl-(1<->1)-ceramide.
Cofactor Name=Mg(2+); Xref=ChEBI:CHEBI:18420;
Function Transfers N-acetylgalactosamine onto globotriaosylceramide. {ECO:0000269|PubMed:9417047}.
Pathway Protein modification; protein glycosylation.
Similarity Belongs to the glycosyltransferase 31 family. {ECO:0000305}.
Subcellular Location Golgi apparatus membrane {ECO:0000250}; Single-pass type II membrane protein {ECO:0000250}.
Tissue Specificity Detected in brain, ovary, uterus and stomach. {ECO:0000269|PubMed:9417047}.
Web Resource Name=Functional Glycomics Gateway - GTase; Note=b3GalT3; URL="http://www.functionalglycomics.org/glycomics/molecule/jsp/glycoEnzyme/viewGlycoEnzyme.jsp?gbpId=gt_mou_456";

Identical and Related Proteins

Unique RefSeq proteins for LMP003478 (as displayed in Record Overview)

Protein GI Database Accession Length Protein Name
9910138 RefSeq NP_064410 331 UDP-GalNAc:beta-1,3-N-acetylgalactosaminyltransferase 1

Identical Sequences to LMP003478 proteins

Reference Database Accession Length Protein Name
GI:9910138 DBBJ BAB68687.1 331 UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase III [Mus spicilegus]
GI:9910138 DBBJ BAC40336.1 331 unnamed protein product [Mus musculus]
GI:9910138 GenBank EDL15496.1 331 UDP-GalNAc:betaGlcNAc beta 1,3-galactosaminyltransferase, polypeptide 1 [Mus musculus]
GI:9910138 RefSeq XP_006501592.1 331 PREDICTED: UDP-GalNAc:beta-1,3-N-acetylgalactosaminyltransferase 1 isoform X1 [Mus musculus]
GI:9910138 SwissProt Q793U7.1 331 RecName: Full=UDP-GalNAc:beta-1,3-N-acetylgalactosaminyltransferase 1; Short=Beta-1,3-GalNAc-T1; AltName: Full=Beta-1,3-galactosyltransferase 3; Short=Beta-1,3-GalTase 3; Short=Beta3Gal-T3; Short=Beta3GalT3; Short=b3Gal-T3; AltName: Full=Beta-3-Gx-T3; AltName: Full=Galactosylgalactosylglucosylceramide beta-D-acetyl-galactosaminyltransferase; AltName: Full=Globoside synthase; AltName: Full=UDP-N-acetylgalactosamine:globotriaosylceramide beta-1,3-N-acetylgalactosaminyltransferase [Mus spicilegus]
GI:9910138 SwissProt Q920V1.2 331 RecName: Full=UDP-GalNAc:beta-1,3-N-acetylgalactosaminyltransferase 1; Short=Beta-1,3-GalNAc-T1; AltName: Full=Beta-1,3-galactosyltransferase 3; Short=Beta-1,3-GalTase 3; Short=Beta3Gal-T3; Short=Beta3GalT3; Short=b3Gal-T3; AltName: Full=Beta-3-Gx-T3; AltName: Full=Galactosylgalactosylglucosylceramide beta-D-acetyl-galactosaminyltransferase; AltName: Full=Globoside synthase; AltName: Full=UDP-N-acetylgalactosamine:globotriaosylceramide beta-1,3-N-acetylgalactosaminyltransferase [Mus musculus]

Related Sequences to LMP003478 proteins

Reference Database Accession Length Protein Name
GI:9910138 DBBJ BAB68680.1 331 UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase III [Mus musculus musculus]
GI:9910138 DBBJ BAB68681.1 331 UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase III [Mus musculus castaneus]
GI:9910138 DBBJ BAB68682.1 331 UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase III [Mus musculus molossinus]
GI:9910138 DBBJ BAB68684.1 331 UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase III [Mus musculus molossinus]
GI:9910138 DBBJ BAB68686.1 331 UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase III [Mus musculus musculus]
GI:9910138 RefSeq XP_005085746.1 331 PREDICTED: UDP-GalNAc:beta-1,3-N-acetylgalactosaminyltransferase 1 [Mesocricetus auratus]