Gene/Proteome Database (LMPD)

LMPD ID
LMP003675
Gene ID
2867
Species
Homo sapiens (Human)
Gene Name
free fatty acid receptor 2
Gene Symbol
FFAR2
Synonyms
FFA2R; GPR43
Chromosome
19
Map Location
19q13.1
Summary
This gene encodes a member of the GP40 family of G protein-coupled receptors that are clustered together on chromosome 19. The encoded protein is a receptor for short chain free fatty acids and may be involved in the inflammatory response and in regulating lipid plasma levels. [provided by RefSeq, Apr 2009]
Orthologs
View orthologs and multiple alignments for FFAR2

Proteins

free fatty acid receptor 2
Refseq ID NP_005297
Protein GI 4885333
UniProt ID O15552
mRNA ID NM_005306
Length 330
RefSeq Status REVIEWED
MLPDWKSSLILMAYIIIFLTGLPANLLALRAFVGRIRQPQPAPVHILLLSLTLADLLLLLLLPFKIIEAASNFRWYLPKVVCALTSFGFYSSIYCSTWLLAGISIERYLGVAFPVQYKLSRRPLYGVIAALVAWVMSFGHCTIVIIVQYLNTTEQVRSGNEITCYENFTDNQLDVVLPVRLELCLVLFFIPMAVTIFCYWRFVWIMLSQPLVGAQRRRRAVGLAVVTLLNFLVCFGPYNVSHLVGYHQRKSPWWRSIAVVFSSLNASLDPLLFYFSSSVVRRAFGRGLQVLRNQGSSLLGRRGKDTAEGTNEDRGVGQGEGMPSSDFTTE

Gene Information

Entrez Gene ID
2867
Gene Name
free fatty acid receptor 2
Gene Symbol
FFAR2
Species
Homo sapiens

Gene Ontology (GO Annotations)

GO ID Source Type Description
GO:0042995 IEA:Ensembl C cell projection
GO:0016021 IEA:UniProtKB-KW C integral component of membrane
GO:0004930 IEA:UniProtKB-KW F G-protein coupled receptor activity
GO:0071398 IEA:Ensembl P cellular response to fatty acid

KEGG Pathway Links

KEGG Pathway ID Description
hsa04024 cAMP signaling pathway
ko04024 cAMP signaling pathway

REACTOME Pathway Links

REACTOME Pathway ID Description
REACT_21268 Free fatty acid receptors

Domain Information

InterPro Annotations

Accession Description
IPR013312 G protein-coupled receptor 40-related receptor
IPR000276 G protein-coupled receptor, rhodopsin-like
IPR017452 GPCR, rhodopsin-like, 7TM

UniProt Annotations

Entry Information

Gene Name
free fatty acid receptor 2
Protein Entry
FFAR2_HUMAN
UniProt ID
O15552
Species
Human

Identical and Related Proteins

Unique RefSeq proteins for LMP003675 (as displayed in Record Overview)

Protein GI Database Accession Length Protein Name
4885333 RefSeq NP_005297 330 free fatty acid receptor 2

Identical Sequences to LMP003675 proteins

Reference Database Accession Length Protein Name
GI:4885333 DBBJ BAH86809.1 330 free fatty acid receptor 2 [Homo sapiens]
GI:4885333 GenBank ABY09760.1 330 Sequence 2 from patent US 7303889
GI:4885333 GenBank ABY87913.1 330 free fatty acid receptor 2 [Homo sapiens]
GI:4885333 GenBank ACH30195.1 330 Sequence 258 from patent US 7410777
GI:4885333 GenBank AHD75704.1 330 Sequence 18087 from patent US 8586006
GI:4885333 GenBank AIC48877.1 330 FFAR2, partial [synthetic construct]

Related Sequences to LMP003675 proteins

Reference Database Accession Length Protein Name
GI:4885333 DBBJ BAG74050.1 330 free fatty acid receptor 2, partial [synthetic construct]
GI:4885333 GenBank AAP64878.1 330 Sequence 276 from patent US 6555339
GI:4885333 GenBank AAH96201.1 330 Free fatty acid receptor 2 [Homo sapiens]
GI:4885333 GenBank AAH95535.1 329 FFAR2 protein, partial [Homo sapiens]
GI:4885333 GenBank ACH30200.1 330 Sequence 276 from patent US 7410777
GI:4885333 RefSeq XP_003816199.1 330 PREDICTED: free fatty acid receptor 2 [Pan paniscus]