Gene/Proteome Database (LMPD)
LMPD ID
LMP003786
Gene ID
Species
Mus musculus (Mouse)
Gene Name
acid phosphatase 6, lysophosphatidic
Gene Symbol
Synonyms
5730559A09Rik; ACPL1; AU022842; mPACPL1
Alternate Names
lysophosphatidic acid phosphatase type 6; PACPL1; acid phosphatase like 1; acid phosphatase-like protein 1
Chromosome
3
Map Location
3 F2.1|3
EC Number
3.1.3.2
Proteins
| lysophosphatidic acid phosphatase type 6 precursor | |
|---|---|
| Refseq ID | NP_062774 |
| Protein GI | 66773165 |
| UniProt ID | Q8BP40 |
| mRNA ID | NM_019800 |
| Length | 418 |
| RefSeq Status | VALIDATED |
| MRVWVPVGVLTSLAYCFHQRRVALAEQRAPNGQRPVDRNLLELKMVQVVFRHGARSPLKPLPLEEQVEWNPKLLEIPPQTRFDYTVTNLAGGPKPHSHYDTEYRKTTLRGGVLAGQLTKVGMQQMFALGEKLRKNYVEDIPFLSPVYNPQEVFIRSTNMFRNLESTRCLLAGLFQHQKGSAVIHTDEASSEVLYPNYQSCWVLKEKTRGRKKAAISQPGISEDLEKVKTGVGINNGDDVDFFVLLDNVAAEQVHSLLNCPALERFAQLIEQRAVDMALYVVEQEDRESIQMAVGPFLHILEGNLLKTVDPTTAPSKTRKMYLYATHDVTLLPMLLALGIFDQKWPPFAVDLTMELYQHQESKEWFVQLFYNGKEQVPRGCPDKLCPLDKFLNTMSVYSVSPEKYRTLCSKTRIVELGE | |
| transit_peptide: 1..25 inference: non-experimental evidence, no additional details recorded note: Mitochondrion (By similarity); propagated from UniProtKB/Swiss-Prot (Q8BP40.1) calculated_mol_wt: 2873 peptide sequence: MRVWVPVGVLTSLAYCFHQRRVALA mat_peptide: 26..418 product: Lysophosphatidic acid phosphatase type 6 experiment: experimental evidence, no additional details recorded note: propagated from UniProtKB/Swiss-Prot (Q8BP40.1) calculated_mol_wt: 44770 peptide sequence: EQRAPNGQRPVDRNLLELKMVQVVFRHGARSPLKPLPLEEQVEWNPKLLEIPPQTRFDYTVTNLAGGPKPHSHYDTEYRKTTLRGGVLAGQLTKVGMQQMFALGEKLRKNYVEDIPFLSPVYNPQEVFIRSTNMFRNLESTRCLLAGLFQHQKGSAVIHTDEASSEVLYPNYQSCWVLKEKTRGRKKAAISQPGISEDLEKVKTGVGINNGDDVDFFVLLDNVAAEQVHSLLNCPALERFAQLIEQRAVDMALYVVEQEDRESIQMAVGPFLHILEGNLLKTVDPTTAPSKTRKMYLYATHDVTLLPMLLALGIFDQKWPPFAVDLTMELYQHQESKEWFVQLFYNGKEQVPRGCPDKLCPLDKFLNTMSVYSVSPEKYRTLCSKTRIVELGE | |
Gene Information
Entrez Gene ID
Gene Name
acid phosphatase 6, lysophosphatidic
Gene Symbol
Species
Mus musculus
Gene Ontology (GO Annotations)
| GO ID | Source | Type | Description |
|---|---|---|---|
| GO:0005739 | IDA:MGI | C | mitochondrion |
| GO:0003993 | IEA:UniProtKB-EC | F | acid phosphatase activity |
| GO:0052642 | ISS:UniProtKB | F | lysophosphatidic acid phosphatase activity |
| GO:0016311 | ISS:GOC | P | dephosphorylation |
| GO:0002244 | IGI:MGI | P | hematopoietic progenitor cell differentiation |
| GO:2001311 | ISS:UniProtKB | P | lysobisphosphatidic acid metabolic process |
KEGG Pathway Links
| KEGG Pathway ID | Description |
|---|---|
| mmu00740 | Riboflavin metabolism |
BIOCYC Pathway Links
| BIOCYC Pathway ID | Description |
|---|---|
| NAD-BIOSYNTHESIS-II | NAD salvage pathway II |
| PWY-6348 | phosphate acquisition |
| PWY-6355 | phosphate acquisition II |
Domain Information
UniProt Annotations
Entry Information
Gene Name
acid phosphatase 6, lysophosphatidic
Protein Entry
PPA6_MOUSE
UniProt ID
Species
Mouse
Comments
| Comment Type | Description |
|---|---|
| Alternative Products | Event=Alternative splicing; Named isoforms=2; Name=1; IsoId=Q8BP40-1; Sequence=Displayed; Name=2; IsoId=Q8BP40-2; Sequence=VSP_014123, VSP_014124; Note=No experimental confirmation available.; |
| Catalytic Activity | A phosphate monoester + H(2)O = an alcohol + phosphate. |
| Function | Hydrolyzes lysophosphatidic acid (LPA) containing a medium length fatty acid chain to the corresponding monoacylglycerol. Has highest activity with lysophosphatidic acid containing myristate (C14:0), monounsaturated oleate (C18:1) or palmitate (C16:0), and lower activity with C18:0 and C6:0 lysophosphatidic acid (By similarity). {ECO:0000250}. |
| Sequence Caution | Sequence=AAF20010.1; Type=Frameshift; Positions=418; Evidence={ECO:0000305}; Sequence=BAA94308.1; Type=Frameshift; Positions=25; Evidence={ECO:0000305}; |
| Similarity | Belongs to the histidine acid phosphatase family. {ECO:0000305}. |
| Subcellular Location | Mitochondrion {ECO:0000250}. |
| Subunit | Monomer. {ECO:0000250}. |
Identical and Related Proteins
Unique RefSeq proteins for LMP003786 (as displayed in Record Overview)
| Protein GI | Database | Accession | Length | Protein Name |
|---|---|---|---|---|
| 66773165 | RefSeq | NP_062774 | 418 | lysophosphatidic acid phosphatase type 6 precursor |
Identical Sequences to LMP003786 proteins
| Reference | Database | Accession | Length | Protein Name |
|---|---|---|---|---|
| GI:66773165 | DBBJ | BAE42654.1 | 418 | unnamed protein product [Mus musculus] |
| GI:66773165 | DBBJ | BAE38147.1 | 418 | unnamed protein product [Mus musculus] |
| GI:66773165 | DBBJ | BAE35722.1 | 418 | unnamed protein product [Mus musculus] |
| GI:66773165 | GenBank | AAH47276.1 | 418 | Acp6 protein [Mus musculus] |
| GI:66773165 | GenBank | EDL38932.1 | 418 | acid phosphatase 6, lysophosphatidic [Mus musculus] |
| GI:66773165 | SwissProt | Q8BP40.1 | 418 | RecName: Full=Lysophosphatidic acid phosphatase type 6; AltName: Full=Acid phosphatase 6, lysophosphatidic; AltName: Full=Acid phosphatase-like protein 1; AltName: Full=PACPL1; Flags: Precursor [Mus musculus] |
Related Sequences to LMP003786 proteins
| Reference | Database | Accession | Length | Protein Name |
|---|---|---|---|---|
| GI:66773165 | DBBJ | BAA94308.1 | 374 | mPACPL1 [Mus musculus] |
| GI:66773165 | GenBank | AAH99131.1 | 413 | Acid phosphatase 6, lysophosphatidic [Rattus norvegicus] |
| GI:66773165 | GenBank | EDL85592.1 | 413 | acid phosphatase 6, lysophosphatidic [Rattus norvegicus] |
| GI:66773165 | RefSeq | NP_001026815.1 | 413 | lysophosphatidic acid phosphatase type 6 [Rattus norvegicus] |
| GI:66773165 | RefSeq | XP_005084285.1 | 418 | PREDICTED: lysophosphatidic acid phosphatase type 6 [Mesocricetus auratus] |
| GI:66773165 | RefSeq | XP_006982662.1 | 418 | PREDICTED: lysophosphatidic acid phosphatase type 6 [Peromyscus maniculatus bairdii] |