Gene/Proteome Database (LMPD)

LMPD ID
LMP003821
Gene ID
103161
Species
Mus musculus (Mouse)
Gene Name
apolipoprotein F
Gene Symbol
Apof
Synonyms
AI255964
Alternate Names
apolipoprotein F; LVIF; apo-F; leukemia virus-inactivating factor
Chromosome
10
Map Location
10 D3|10 76.5 cM

Proteins

apolipoprotein F precursor
Refseq ID NP_598758
Protein GI 19527216
UniProt ID Q91V80
mRNA ID NM_133997
Length 326
RefSeq Status PROVISIONAL
MAGLYGCSAPDMHSLRLILMSIQLLCYLLLCPVDATSHGEATSVSTVLPPSKLGYQMQTSDKPLSCQMLLPKSLPGFTYMPPVSKFLVGLALRNALEAAGCQAEVWALQLQLYRLGGVEATQALIHHLQELQKSGHTDREVSVDALSSALQLLAWEQPGPKRAKRSISNTDCDNDQEQSVHNVVDLLPAVGTYYNLGTALYYAIKNCSDKAKERGRDGAIDLGYDLLMAMVGASGGPAGAVITAALKPAMKAGVQRLIQYYYDEKEVTTPQPEVTTHQPETGKDATTDIGVVEEIAMSNFVSEVESTTSNWEWPLLKNYGVLAYKR
sig_peptide: 1..35 inference: COORDINATES: ab initio prediction:SignalP:4.0 calculated_mol_wt: 3826 peptide sequence: MAGLYGCSAPDMHSLRLILMSIQLLCYLLLCPVDA

Gene Information

Entrez Gene ID
103161
Gene Name
apolipoprotein F
Gene Symbol
Apof
Species
Mus musculus

Gene Ontology (GO Annotations)

GO ID Source Type Description
GO:0034364 IEA:UniProtKB-KW C high-density lipoprotein particle
GO:0034362 IEA:UniProtKB-KW C low-density lipoprotein particle
GO:0033344 IGI:MGI P cholesterol efflux
GO:0008203 IMP:MGI P cholesterol metabolic process
GO:0006641 IMP:MGI P triglyceride metabolic process

Domain Information

InterPro Annotations

Accession Description
IPR026114 Apolipoprotein F

UniProt Annotations

Entry Information

Gene Name
apolipoprotein F
Protein Entry
APOF_MOUSE
UniProt ID
Q91V80
Species
Mouse

Comments

Comment Type Description
Function Minor apolipoprotein that associates with LDL. Inhibits cholesteryl ester transfer protein (CETP) activity and appears to be an important regulator of cholesterol transport. Also associates to a lesser degree with VLDL, Apo-AI and Apo-AII (By similarity). {ECO:0000250}.
Sequence Caution Sequence=AAH10815.1; Type=Erroneous initiation; Evidence={ECO:0000305}; Sequence=AAH22795.1; Type=Erroneous initiation; Evidence={ECO:0000305}; Sequence=AAH24769.1; Type=Erroneous initiation; Evidence={ECO:0000305}; Sequence=AAH25827.1; Type=Erroneous initiation; Evidence={ECO:0000305}; Sequence=AAL06339.1; Type=Erroneous initiation; Evidence={ECO:0000305}; Sequence=AAL06340.1; Type=Erroneous initiation; Evidence={ECO:0000305}; Sequence=AAL06341.1; Type=Erroneous initiation; Evidence={ECO:0000305};
Subcellular Location Secreted {ECO:0000250}.
Tissue Specificity Liver. {ECO:0000269|PubMed:11836406}.

Identical and Related Proteins

Unique RefSeq proteins for LMP003821 (as displayed in Record Overview)

Protein GI Database Accession Length Protein Name
19527216 RefSeq NP_598758 326 apolipoprotein F precursor

Identical Sequences to LMP003821 proteins

Reference Database Accession Length Protein Name
GI:19527216 GenBank AAL06340.1 326 apolipoprotein F [Mus musculus]
GI:19527216 GenBank AAL06341.1 326 apolipoprotein F [Mus musculus]
GI:19527216 GenBank AAH22795.1 326 Apolipoprotein F [Mus musculus]
GI:19527216 GenBank AAH24769.1 326 Apolipoprotein F [Mus musculus]
GI:19527216 GenBank AAH25827.1 326 Apolipoprotein F [Mus musculus]
GI:19527216 GenBank EDL24552.1 326 apolipoprotein F [Mus musculus]

Related Sequences to LMP003821 proteins

Reference Database Accession Length Protein Name
GI:19527216 GenBank EGW12498.1 303 Apolipoprotein F [Cricetulus griseus]
GI:19527216 GenBank ERE91745.1 303 apolipoprotein F-like protein [Cricetulus griseus]
GI:19527216 RefSeq XP_005079785.1 314 PREDICTED: LOW QUALITY PROTEIN: apolipoprotein F [Mesocricetus auratus]
GI:19527216 RefSeq XP_006987413.1 318 PREDICTED: LOW QUALITY PROTEIN: apolipoprotein F-like [Peromyscus maniculatus bairdii]
GI:19527216 RefSeq XP_007607752.1 397 PREDICTED: LOW QUALITY PROTEIN: apolipoprotein F isoform X2 [Cricetulus griseus]
GI:19527216 SwissProt Q91V80.2 315 RecName: Full=Apolipoprotein F; Short=Apo-F; AltName: Full=Leukemia virus-inactivating factor; Short=LVIF; Flags: Precursor [Mus musculus]