Gene/Proteome Database (LMPD)
LMPD ID
LMP003829
Gene ID
Species
Mus musculus (Mouse)
Gene Name
phosphatidylinositol glycan anchor biosynthesis, class H
Gene Symbol
Synonyms
2210416H01Rik; A930028P05Rik
Alternate Names
phosphatidylinositol N-acetylglucosaminyltransferase subunit H; PIG-H; phosphatidylinositol glycan, class H; phosphatidylinositol-glycan biosynthesis class H protein
Chromosome
12
Map Location
12 D2|12 35.51 cM
EC Number
2.4.1.198
Proteins
| phosphatidylinositol N-acetylglucosaminyltransferase subunit H | |
|---|---|
| Refseq ID | NP_084264 |
| Protein GI | 41872422 |
| UniProt ID | Q5M9N4 |
| mRNA ID | NM_029988 |
| Length | 188 |
| RefSeq Status | VALIDATED |
| MEDEKSFSDICGGRLALRCRYYSPYCREFGLSSARLSLCSLTAVTCAVWLAAYGLFTLCENSMVLSATIFITILGLLGYLHFVKIDQETLLIIDSLGIQMTSSYASGKESTTFIEMDKVKDIIINEAIYMQKVIYYLCILLKEPGKPHEISRVVPVFQSAKPRLDCLIEVYRSCQEVLAHQKATATSL | |
Gene Information
Entrez Gene ID
Gene Name
phosphatidylinositol glycan anchor biosynthesis, class H
Gene Symbol
Species
Mus musculus
Gene Ontology (GO Annotations)
| GO ID | Source | Type | Description |
|---|---|---|---|
| GO:0000506 | IEA:Ensembl | C | glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex |
| GO:0017176 | IEA:UniProtKB-EC | F | phosphatidylinositol N-acetylglucosaminyltransferase activity |
| GO:0006506 | IEA:UniProtKB-UniPathway | P | GPI anchor biosynthetic process |
KEGG Pathway Links
| KEGG Pathway ID | Description |
|---|---|
| ko00563 | Glycosylphosphatidylinositol(GPI)-anchor biosynthesis |
| mmu00563 | Glycosylphosphatidylinositol(GPI)-anchor biosynthesis |
| mmu01100 | Metabolic pathways |
REACTOME Pathway Links
| REACTOME Pathway ID | Description |
|---|---|
| 5893244 | Synthesis of glycosylphosphatidylinositol (GPI) |
Domain Information
InterPro Annotations
| Accession | Description |
|---|---|
| IPR019328 | GPI-GlcNAc transferase complex, PIG-H component, conserved domain |
UniProt Annotations
Entry Information
Gene Name
phosphatidylinositol glycan anchor biosynthesis, class H
Protein Entry
PIGH_MOUSE
UniProt ID
Species
Mouse
Comments
| Comment Type | Description |
|---|---|
| Catalytic Activity | UDP-N-acetyl-D-glucosamine + 1-phosphatidyl- 1D-myo-inositol = UDP + 6-(N-acetyl-alpha-D-glucosaminyl)-1- phosphatidyl-1D-myo-inositol. |
| Function | Part of the complex catalyzing the transfer of N- acetylglucosamine from UDP-N-acetylglucosamine to phosphatidylinositol, the first step of GPI biosynthesis. {ECO:0000250}. |
| Pathway | Glycolipid biosynthesis; glycosylphosphatidylinositol- anchor biosynthesis. |
| Similarity | Belongs to the PIGH family. {ECO:0000305}. |
| Subcellular Location | Cytoplasm {ECO:0000250}. |
| Subunit | Associates with PIGA, PIGC, PIGP, PIGQ and DPM2. The latter is not essential for activity (By similarity). {ECO:0000250}. |
Identical and Related Proteins
Unique RefSeq proteins for LMP003829 (as displayed in Record Overview)
| Protein GI | Database | Accession | Length | Protein Name |
|---|---|---|---|---|
| 41872422 | RefSeq | NP_084264 | 188 | phosphatidylinositol N-acetylglucosaminyltransferase subunit H |
Identical Sequences to LMP003829 proteins
| Reference | Database | Accession | Length | Protein Name |
|---|---|---|---|---|
| GI:41872422 | DBBJ | BAE39904.1 | 188 | unnamed protein product [Mus musculus] |
| GI:41872422 | GenBank | AAH86806.1 | 188 | Phosphatidylinositol glycan anchor biosynthesis, class H [Mus musculus] |
| GI:41872422 | SwissProt | Q5M9N4.1 | 188 | RecName: Full=Phosphatidylinositol N-acetylglucosaminyltransferase subunit H; AltName: Full=Phosphatidylinositol-glycan biosynthesis class H protein; Short=PIG-H [Mus musculus] |
Related Sequences to LMP003829 proteins
| Reference | Database | Accession | Length | Protein Name |
|---|---|---|---|---|
| GI:41872422 | GenBank | EDM03717.1 | 188 | phosphatidylinositol glycan, class H (predicted), isoform CRA_a [Rattus norvegicus] |
| GI:41872422 | GenBank | EGV91866.1 | 188 | Phosphatidylinositol N-acetylglucosaminyltransferase subunit H [Cricetulus griseus] |
| GI:41872422 | GenBank | ERE72913.1 | 188 | phosphatidylinositol N-acetylglucosaminyltransferase subunit H-like protein [Cricetulus griseus] |
| GI:41872422 | RefSeq | NP_001102184.1 | 188 | phosphatidylinositol N-acetylglucosaminyltransferase subunit H [Rattus norvegicus] |
| GI:41872422 | RefSeq | XP_003498315.1 | 188 | PREDICTED: phosphatidylinositol N-acetylglucosaminyltransferase subunit H isoform X1 [Cricetulus griseus] |
| GI:41872422 | RefSeq | XP_005343315.1 | 188 | PREDICTED: phosphatidylinositol N-acetylglucosaminyltransferase subunit H [Microtus ochrogaster] |