Gene/Proteome Database (LMPD)

LMPD ID
LMP003927
Gene ID
67556
Species
Mus musculus (Mouse)
Gene Name
phosphatidylinositol glycan anchor biosynthesis, class M
Gene Symbol
Pigm
Synonyms
4933437L05Rik; AI644422; AV302080; C920011G20Rik
Alternate Names
GPI mannosyltransferase 1; PIG-M; GPI-MT-I; GPI mannosyltransferase I; phosphatidylinositol glycan, class M; phosphatidylinositol-glycan biosynthesis class M protein
Chromosome
1
Map Location
1 H3|1 79.73 cM
EC Number
2.4.1.-

Proteins

GPI mannosyltransferase 1
Refseq ID NP_080510
Protein GI 19920329
UniProt ID Q8C2R7
mRNA ID NM_026234
Length 423
RefSeq Status VALIDATED
MSYPMHWGEWILNFRVPPAGVFGVAFLARVALVFYGVFQDRTLLVRYTDIDYHVFTDAARFVTEGRSPYLRATYRYTPLLSWLLTPNVYLSELFGKFLFISCDLLTAFLLYRLLLLKGLGRRQACGYCVFWLLNPLPMAVSSRGNADSIVASLVLSTLYFIEKRLIACAAVFYGFAVHMKMYPVTYILPIALHLRPERDDDERLRQARFSFQARLYDFLRRLCSWAVLLFVAVAGLTFVALSFGFYYKYGWEFLEHTYFYHLTRRDIRHNFSPYFYMLYLTAESKWSFTLGIAAFLPQFILLSAASFAYYRDLVFCCFLHTSIFVTFNKVCTSQYFLWYLCLLPLVMPLVRMPWKRAVVLLLFWFIGQALWLAPAYVLEFQGKNTFLFIWLAGLFFLLINCSILIQIISHYKEDRLTERIKYD

Gene Information

Entrez Gene ID
67556
Gene Name
phosphatidylinositol glycan anchor biosynthesis, class M
Gene Symbol
Pigm
Species
Mus musculus

Gene Ontology (GO Annotations)

GO ID Source Type Description
GO:0005789 IEA:InterPro C endoplasmic reticulum membrane
GO:0016021 IEA:UniProtKB-KW C integral component of membrane
GO:0000030 IEA:Ensembl F mannosyltransferase activity
GO:0006506 IEA:UniProtKB-UniPathway P GPI anchor biosynthetic process

KEGG Pathway Links

KEGG Pathway ID Description
mmu00563 Glycosylphosphatidylinositol(GPI)-anchor biosynthesis
mmu01100 Metabolic pathways

REACTOME Pathway Links

REACTOME Pathway ID Description
5893244 Synthesis of glycosylphosphatidylinositol (GPI)

Domain Information

InterPro Annotations

Accession Description
IPR007704 Mannosyltransferase, DXD

UniProt Annotations

Entry Information

Gene Name
phosphatidylinositol glycan anchor biosynthesis, class M
Protein Entry
PIGM_MOUSE
UniProt ID
Q8C2R7
Species
Mouse

Comments

Comment Type Description
Function Mannosyltransferase involved in glycosylphosphatidylinositol-anchor biosynthesis. Transfers the first alpha-1,4-mannose to GlcN-acyl-PI during GPI precursor assembly (By similarity). {ECO:0000250}.
Pathway Glycolipid biosynthesis; glycosylphosphatidylinositol- anchor biosynthesis.
Similarity Belongs to the PIGM family. {ECO:0000305}.
Subcellular Location Endoplasmic reticulum membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}.

Identical and Related Proteins

Unique RefSeq proteins for LMP003927 (as displayed in Record Overview)

Protein GI Database Accession Length Protein Name
19920329 RefSeq NP_080510 423 GPI mannosyltransferase 1

Identical Sequences to LMP003927 proteins

Reference Database Accession Length Protein Name
GI:19920329 DBBJ BAB31275.1 423 unnamed protein product [Mus musculus]
GI:19920329 DBBJ BAC30585.1 423 unnamed protein product [Mus musculus]
GI:19920329 DBBJ BAC37857.1 423 unnamed protein product [Mus musculus]
GI:19920329 GenBank AAH83115.1 423 Phosphatidylinositol glycan anchor biosynthesis, class M [Mus musculus]
GI:19920329 GenBank EDL39016.1 423 phosphatidylinositol glycan anchor biosynthesis, class M [Mus musculus]
GI:19920329 SwissProt Q8C2R7.2 423 RecName: Full=GPI mannosyltransferase 1; AltName: Full=GPI mannosyltransferase I; Short=GPI-MT-I; AltName: Full=Phosphatidylinositol-glycan biosynthesis class M protein; Short=PIG-M [Mus musculus]

Related Sequences to LMP003927 proteins

Reference Database Accession Length Protein Name
GI:19920329 DBBJ BAC40156.1 423 unnamed protein product [Mus musculus]
GI:19920329 GenBank AAH05650.1 423 Phosphatidylinositol glycan anchor biosynthesis, class M [Mus musculus]
GI:19920329 GenBank EDL94711.1 423 phosphatidylinositol glycan, class M [Rattus norvegicus]
GI:19920329 RefSeq NP_077058.1 423 GPI mannosyltransferase 1 [Rattus norvegicus]
GI:19920329 RefSeq XP_008772129.1 423 PREDICTED: GPI mannosyltransferase 1 [Rattus norvegicus]
GI:19920329 SwissProt Q9EQY6.1 423 RecName: Full=GPI mannosyltransferase 1; AltName: Full=GPI mannosyltransferase I; Short=GPI-MT-I; AltName: Full=Phosphatidylinositol-glycan biosynthesis class M protein; Short=PIG-M [Rattus norvegicus]