Gene/Proteome Database (LMPD)

LMPD ID
LMP003995
Gene ID
72692
Species
Mus musculus (Mouse)
Gene Name
heterogeneous nuclear ribonucleoprotein L-like
Gene Symbol
Hnrnpll
Synonyms
2510028H02Rik; 2810036L13Rik; AI256697; AI852082; Hnrpll
Alternate Names
heterogeneous nuclear ribonucleoprotein L-like
Chromosome
17
Map Location
17 E3|17

Proteins

heterogeneous nuclear ribonucleoprotein L-like
Refseq ID NP_659051
Protein GI 110347535
UniProt ID Q921F4
mRNA ID NM_144802
Length 591
RefSeq Status VALIDATED
MSSSSSSSPKEETYEEDREFESQAKRLKTEEGEIVYSAEESENRQEATPQAGSDSDSGGGDGGDGDGGSGGGGDGEEGEGGEEGDEGDGDEGGSGGDEGGSGGGPRSMPLSTEGGGSHHKVSVSPVVHVRGLCESVVEADLVEALEKFGTICYVMMMPFKRQALVEFENIDSAKECVTFAADVPVYIAGQQAFFNYSTSKRITRPGNTDDPSGGNKVLLLSIQNPLYPITVDVLYTVCNPVGKVQRIVIFKRNGIQAMVEFESVLCAQKAKAALNGADIYAGCCTLKIEYARPTRLNVIRNDNDSWDYTKPYLGRRDRGKGRQRQAILGDHPSSFRHDGYGSHGPLLPLPSRYRMGSRDTPELVAYPLPQASSSYMHGGSPSGSVVMVSGLHQLKMNCSRVFNLFCLYGNIEKVKFMKTIPGTALVEMGDEYAVERAVTHLNNVKLFGKRLNVCVSKQHSVVPSQIFELEDGTSSYKDFAMSKNNRFTSAGQASKNIIQPPSCVLHYYNVPLCVTEETFTKLCNDHEVLPFIKYKVFDAKASAKTLSGLLEWKCKTDAVEALTALNHYQIRVPNGSNPYTLKLCFSTSSHL

Gene Information

Entrez Gene ID
72692
Gene Name
heterogeneous nuclear ribonucleoprotein L-like
Gene Symbol
Hnrnpll
Species
Mus musculus

Gene Ontology (GO Annotations)

GO ID Source Type Description
GO:0005634 IEA:InterPro C nucleus
GO:0030529 IEA:UniProtKB-KW C ribonucleoprotein complex
GO:0003729 ISS:UniProtKB F mRNA binding
GO:0000166 IEA:InterPro F nucleotide binding
GO:0006397 IEA:InterPro P mRNA processing
GO:0033120 ISS:UniProtKB P positive regulation of RNA splicing

Domain Information

InterPro Annotations

Accession Description
IPR006536 HnRNP-L/PTB/hephaestus splicing factor
IPR012677 Nucleotide-binding alpha-beta plait domain
IPR000504 RNA recognition motif domain

UniProt Annotations

Entry Information

Gene Name
heterogeneous nuclear ribonucleoprotein L-like
Protein Entry
HNRLL_MOUSE
UniProt ID
Q921F4
Species
Mouse

Comments

Comment Type Description
Alternative Products Event=Alternative splicing; Named isoforms=3; Name=1; IsoId=Q921F4-1; Sequence=Displayed; Name=2; IsoId=Q921F4-4; Sequence=VSP_013290, VSP_013291; Note=No experimental confirmation available.; Name=3; IsoId=Q921F4-5; Sequence=VSP_026132, VSP_026133;
Function RNA-binding protein that functions as regulator of alternative splicing for multiple target mRNAs, including PTPRC/CD45 and STAT5A. Required for alternative splicing of PTPRC. {ECO:0000269|PubMed:19100700}.
Induction Up-regulated in stimulated T-cells. {ECO:0000269|PubMed:19100700}.
Ptm Isoform 3 is phosphorylated at 'Ser-64'.
Sequence Caution Sequence=BAE27500.1; Type=Erroneous initiation; Evidence={ECO:0000305};
Similarity Contains 3 RRM (RNA recognition motif) domains. {ECO:0000255|PROSITE-ProRule:PRU00176}.
Subunit Interacts with HNRNPL. {ECO:0000250}.

Identical and Related Proteins

Unique RefSeq proteins for LMP003995 (as displayed in Record Overview)

Protein GI Database Accession Length Protein Name
110347535 RefSeq NP_659051 591 heterogeneous nuclear ribonucleoprotein L-like

Identical Sequences to LMP003995 proteins

Reference Database Accession Length Protein Name
GI:110347535 SwissProt Q921F4.3 591 RecName: Full=Heterogeneous nuclear ribonucleoprotein L-like [Mus musculus]

Related Sequences to LMP003995 proteins

Reference Database Accession Length Protein Name
GI:110347535 DBBJ BAE27500.1 670 unnamed protein product, partial [Mus musculus]
GI:110347535 GenBank AAH12849.2 594 Hnrpll protein [Mus musculus]
GI:110347535 RefSeq XP_001063027.2 591 PREDICTED: heterogeneous nuclear ribonucleoprotein L-like [Rattus norvegicus]
GI:110347535 RefSeq XP_233805.5 591 PREDICTED: heterogeneous nuclear ribonucleoprotein L-like [Rattus norvegicus]
GI:110347535 RefSeq XP_005073672.1 597 PREDICTED: heterogeneous nuclear ribonucleoprotein L-like isoform X1 [Mesocricetus auratus]
GI:110347535 RefSeq XP_005360824.1 606 PREDICTED: heterogeneous nuclear ribonucleoprotein L-like [Microtus ochrogaster]