Gene/Proteome Database (LMPD)
LMPD ID
LMP004045
Gene ID
Species
Mus musculus (Mouse)
Gene Name
dolichyl-phosphate mannosyltransferase polypeptide 3
Gene Symbol
Synonyms
1110001H19Rik; AV117483
Alternate Names
dolichol-phosphate mannosyltransferase subunit 3; DPM synthase subunit 3; MPD synthase subunit 3; DPM synthase complex subunit 3; mannose-P-dolichol synthase subunit 3; dolichol-phosphate mannose synthase subunit 3; dolichyl-phosphate beta-D-mannosyltransferase subunit 3
Chromosome
3
Map Location
3|3 F2
Proteins
| dolichol-phosphate mannosyltransferase subunit 3 precursor | |
|---|---|
| Refseq ID | NP_081043 |
| Protein GI | 58037125 |
| UniProt ID | Q9D1Q4 |
| mRNA ID | NM_026767 |
| Length | 92 |
| RefSeq Status | VALIDATED |
| MTKLTQWLWGLALLGSAWAALTMGALGLELPFPCREVLWPLPAYLLVSAGCYALGTVGYRVATFHDCEDAARELQSQIVEARADLARRGLRF | |
| sig_peptide: 1..19 inference: COORDINATES: ab initio prediction:SignalP:4.0 calculated_mol_wt: 2147 peptide sequence: MTKLTQWLWGLALLGSAWA | |
Gene Information
Entrez Gene ID
Gene Name
dolichyl-phosphate mannosyltransferase polypeptide 3
Gene Symbol
Species
Mus musculus
Gene Ontology (GO Annotations)
| GO ID | Source | Type | Description |
|---|---|---|---|
| GO:0033185 | ISS:HGNC | C | dolichol-phosphate-mannose synthase complex |
| GO:0030176 | ISS:HGNC | C | integral component of endoplasmic reticulum membrane |
| GO:0004582 | IEA:Ensembl | F | dolichyl-phosphate beta-D-mannosyltransferase activity |
| GO:0006506 | IEA:Ensembl | P | GPI anchor biosynthetic process |
| GO:0097502 | ISS:GOC | P | mannosylation |
| GO:0006486 | IEA:UniProtKB-UniPathway | P | protein glycosylation |
| GO:0031647 | IEA:Ensembl | P | regulation of protein stability |
KEGG Pathway Links
| KEGG Pathway ID | Description |
|---|---|
| mmu01100 | Metabolic pathways |
| ko00510 | N-Glycan biosynthesis |
| mmu00510 | N-Glycan biosynthesis |
REACTOME Pathway Links
| REACTOME Pathway ID | Description |
|---|---|
| 5893246 | Synthesis of dolichyl-phosphate mannose |
Domain Information
InterPro Annotations
| Accession | Description |
|---|---|
| IPR013174 | Dolichol-phosphate mannosyltransferase subunit 3 |
UniProt Annotations
Entry Information
Gene Name
dolichyl-phosphate mannosyltransferase polypeptide 3
Protein Entry
DPM3_MOUSE
UniProt ID
Species
Mouse
Comments
| Comment Type | Description |
|---|---|
| Function | Stabilizer subunit of the dolichol-phosphate mannose (DPM) synthase complex; tethers catalytic subunit DPM1 to the ER. {ECO:0000250}. |
| Pathway | Protein modification; protein glycosylation. |
| Similarity | Belongs to the DPM3 family. {ECO:0000305}. |
| Subcellular Location | Endoplasmic reticulum membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}. |
| Subunit | Component of the dolichol-phosphate mannose (DPM) synthase complex composed of DPM1, DPM2 and DPM3; in the complex associated with DPM1 via its C-terminal domain and with DPM2 via its N-terminal portion. {ECO:0000250}. |
Identical and Related Proteins
Unique RefSeq proteins for LMP004045 (as displayed in Record Overview)
| Protein GI | Database | Accession | Length | Protein Name |
|---|---|---|---|---|
| 58037125 | RefSeq | NP_081043 | 92 | dolichol-phosphate mannosyltransferase subunit 3 precursor |
Identical Sequences to LMP004045 proteins
| Reference | Database | Accession | Length | Protein Name |
|---|---|---|---|---|
| GI:58037125 | DBBJ | BAB22652.1 | 92 | unnamed protein product [Mus musculus] |
| GI:58037125 | GenBank | EDL15217.1 | 92 | mCG17569 [Mus musculus] |
| GI:58037125 | RefSeq | XP_006502046.1 | 92 | PREDICTED: dolichol-phosphate mannosyltransferase subunit 3 isoform X2 [Mus musculus] |
| GI:58037125 | SwissProt | Q9D1Q4.1 | 92 | RecName: Full=Dolichol-phosphate mannosyltransferase subunit 3; AltName: Full=Dolichol-phosphate mannose synthase subunit 3; Short=DPM synthase subunit 3; AltName: Full=Dolichyl-phosphate beta-D-mannosyltransferase subunit 3; AltName: Full=Mannose-P-dolichol synthase subunit 3; Short=MPD synthase subunit 3 [Mus musculus] |
Related Sequences to LMP004045 proteins
| Reference | Database | Accession | Length | Protein Name |
|---|---|---|---|---|
| GI:58037125 | GenBank | EDM00650.1 | 92 | rCG62502 [Rattus norvegicus] |
| GI:58037125 | GenBank | EDM02246.1 | 92 | rCG63436, partial [Rattus norvegicus] |
| GI:58037125 | GenBank | EGV98090.1 | 92 | Dolichol-phosphate mannosyltransferase subunit 3 [Cricetulus griseus] |
| GI:58037125 | GenBank | ERE92268.1 | 92 | dolichol-phosphate mannosyltransferase subunit 3 precursor [Cricetulus griseus] |
| GI:58037125 | RefSeq | NP_001233639.2 | 92 | dolichol-phosphate mannosyltransferase subunit 3 precursor [Cricetulus griseus] |
| GI:58037125 | RefSeq | XP_006502045.1 | 194 | PREDICTED: dolichol-phosphate mannosyltransferase subunit 3 isoform X1 [Mus musculus] |