Gene/Proteome Database (LMPD)

LMPD ID
LMP004120
Gene ID
78134
Species
Mus musculus (Mouse)
Gene Name
lysophosphatidic acid receptor 4
Gene Symbol
Lpar4
Synonyms
5730485F04Rik; Gpr23; LPA4; p2y9
Alternate Names
lysophosphatidic acid receptor 4; LPA-4; LPA receptor 4; P2Y purinoceptor 9; purinergic receptor 9; G protein-coupled receptor 23; G-protein coupled receptor 23
Chromosome
X
Map Location
X D|X

Proteins

lysophosphatidic acid receptor 4
Refseq ID NP_780480
Protein GI 238637326
UniProt ID Q8BLG2
mRNA ID NM_175271
Length 370
RefSeq Status VALIDATED
MGDRRFIDFQFQDLNSSLRPRLGNATANNTCIVDDSFKYNLNGAVYSVVFILGLITNSASLFVFCFRMKMRSETAIFITNLALSDLLFVCTLPFKIFYNFNRHWPFGDTLCKISGTAFLTNIYGSMLFLTCISVDRFLAIVYPFRSRTIRTRRNSAIVCAGVWILVLSGGISASLFSTTNVNNATTTCFEGFSKRVWKTYLSKITIFIEVVGFIIPLILNVSCSSVVLRTLRKPATLSQIGTNKKKVLKMITVHMAVFVVCFVPYNSVLFLYALVRSQAITNCLLERFAKIMYPITLCLATLNCCFDPFIYYFTLESFQKSFYINTHIRMESLFKTETPLTPKPSLPAIQEEVSDQTTNNGGELMLESTF

Gene Information

Entrez Gene ID
78134
Gene Name
lysophosphatidic acid receptor 4
Gene Symbol
Lpar4
Species
Mus musculus

Gene Ontology (GO Annotations)

GO ID Source Type Description
GO:0016021 IEA:UniProtKB-KW C integral component of membrane
GO:0005886 IEA:UniProtKB-KW C plasma membrane
GO:0004930 IEA:UniProtKB-KW F G-protein coupled receptor activity
GO:0008289 IEA:UniProtKB-KW F lipid binding

KEGG Pathway Links

KEGG Pathway ID Description
mmu04151 PI3K-Akt signaling pathway
mmu04015 Rap1 signaling pathway

REACTOME Pathway Links

REACTOME Pathway ID Description
5893741 P2Y receptors

Domain Information

InterPro Annotations

Accession Description
IPR017452 GPCR, rhodopsin-like, 7TM
IPR000276 G protein-coupled receptor, rhodopsin-like

UniProt Annotations

Entry Information

Gene Name
lysophosphatidic acid receptor 4
Protein Entry
LPAR4_MOUSE
UniProt ID
Q8BLG2
Species
Mouse

Comments

Comment Type Description
Function Receptor for lysophosphatidic acid (LPA), a mediator of diverse cellular activities. Transduces a signal by increasing the intracellular calcium ions and by stimulating adenylyl cyclase activity. The rank order of potency for agonists of this receptor is 1-oleoyl- > 1-stearoyl- > 1-palmitoyl- > 1-myristoyl- > 1- alkyl- > 1-alkenyl-LPA (By similarity). {ECO:0000250}.
Similarity Belongs to the G-protein coupled receptor 1 family. {ECO:0000255|PROSITE-ProRule:PRU00521}.
Subcellular Location Cell membrane; Multi-pass membrane protein.

Identical and Related Proteins

Unique RefSeq proteins for LMP004120 (as displayed in Record Overview)

Protein GI Database Accession Length Protein Name
238637326 RefSeq NP_780480 370 lysophosphatidic acid receptor 4

Identical Sequences to LMP004120 proteins

Reference Database Accession Length Protein Name
GI:238637326 GenBank AAI38894.1 370 Lysophosphatidic acid receptor 4 [Mus musculus]
GI:238637326 GenBank AAI38895.1 370 Lysophosphatidic acid receptor 4 [Mus musculus]
GI:238637326 RefSeq XP_005369923.1 370 PREDICTED: lysophosphatidic acid receptor 4 isoform X1 [Microtus ochrogaster]
GI:238637326 RefSeq XP_005369924.1 370 PREDICTED: lysophosphatidic acid receptor 4 isoform X2 [Microtus ochrogaster]
GI:238637326 RefSeq XP_006992676.1 370 PREDICTED: lysophosphatidic acid receptor 4-like [Peromyscus maniculatus bairdii]
GI:238637326 SwissProt Q8BLG2.2 370 RecName: Full=Lysophosphatidic acid receptor 4; Short=LPA receptor 4; Short=LPA-4; AltName: Full=G-protein coupled receptor 23; AltName: Full=P2Y purinoceptor 9; Short=P2Y9; AltName: Full=Purinergic receptor 9 [Mus musculus]

Related Sequences to LMP004120 proteins

Reference Database Accession Length Protein Name
GI:238637326 RefSeq XP_003512757.1 370 PREDICTED: lysophosphatidic acid receptor 4 [Cricetulus griseus]
GI:238637326 RefSeq XP_007651316.1 370 PREDICTED: lysophosphatidic acid receptor 4 [Cricetulus griseus]
GI:238637326 RefSeq XP_007651317.1 370 PREDICTED: lysophosphatidic acid receptor 4 [Cricetulus griseus]
GI:238637326 RefSeq XP_007606990.1 370 PREDICTED: lysophosphatidic acid receptor 4 [Cricetulus griseus]
GI:238637326 RefSeq XP_007606991.1 370 PREDICTED: lysophosphatidic acid receptor 4 [Cricetulus griseus]
GI:238637326 RefSeq XP_007606992.1 370 PREDICTED: lysophosphatidic acid receptor 4 [Cricetulus griseus]