Gene/Proteome Database (LMPD)

LMPD ID
LMP004232
Gene ID
11000
Species
Homo sapiens (Human)
Gene Name
solute carrier family 27 (fatty acid transporter), member 3
Gene Symbol
SLC27A3
Synonyms
ACSVL3; FATP3; VLCS-3
Alternate Names
long-chain fatty acid transport protein 3; FATP-3; fatty acid transport protein 3; solute carrier family 27 member 3; very long-chain acyl-CoA synthetase homolog 3
Chromosome
1
Map Location
1q21.3
EC Number
6.2.1.-

Proteins

long-chain fatty acid transport protein 3
Refseq ID NP_077306
Protein GI 13236579
UniProt ID Q5K4L6
mRNA ID NM_024330
Length 730
RefSeq Status PROVISIONAL
MGVCQRTRAPWKEKSQLERAALGFRKGGSGMFASGWNQTVPIEEAGSMAALLLLPLLLLLPLLLLKLHLWPQLRWLPADLAFAVRALCCKRALRARALAAAAADPEGPEGGCSLAWRLAELAQQRAAHTFLIHGSRRFSYSEAERESNRAARAFLRALGWDWGPDGGDSGEGSAGEGERAAPGAGDAAAGSGAEFAGGDGAARGGGAAAPLSPGATVALLLPAGPEFLWLWFGLAKAGLRTAFVPTALRRGPLLHCLRSCGARALVLAPEFLESLEPDLPALRAMGLHLWAAGPGTHPAGISDLLAEVSAEVDGPVPGYLSSPQSITDTCLYIFTSGTTGLPKAARISHLKILQCQGFYQLCGVHQEDVIYLALPLYHMSGSLLGIVGCMGIGATVVLKSKFSAGQFWEDCQQHRVTVFQYIGELCRYLVNQPPSKAERGHKVRLAVGSGLRPDTWERFVRRFGPLQVLETYGLTEGNVATINYTGQRGAVGRASWLYKHIFPFSLIRYDVTTGEPIRDPQGHCMATSPGEPGLLVAPVSQQSPFLGYAGGPELAQGKLLKDVFRPGDVFFNTGDLLVCDDQGFLRFHDRTGDTFRWKGENVATTEVAEVFEALDFLQEVNVYGVTVPGHEGRAGMAALVLRPPHALDLMQLYTHVSENLPPYARPRFLRLQESLATTETFKQQKVRMANEGFDPSTLSDPLYVLDQAVGAYLPLTTARYSALLAGNLRI

Gene Information

Entrez Gene ID
11000
Gene Name
solute carrier family 27 (fatty acid transporter), member 3
Gene Symbol
SLC27A3
Species
Homo sapiens

Gene Ontology (GO Annotations)

GO ID Source Type Description
GO:0016021 IEA:UniProtKB-KW C integral component of membrane
GO:0016020 IDA:UniProtKB C membrane
GO:0005739 IEA:UniProtKB-KW C mitochondrion
GO:0004321 IEA:Ensembl F fatty-acyl-CoA synthase activity
GO:0016874 IEA:UniProtKB-KW F ligase activity
GO:0000166 IEA:UniProtKB-KW F nucleotide binding
GO:0006631 IEA:UniProtKB-KW P fatty acid metabolic process

Domain Information

InterPro Annotations

Accession Description
IPR025110 AMP-binding enzyme C-terminal domain
IPR020845 AMP-binding, conserved site
IPR000873 AMP-dependent synthetase/ligase

UniProt Annotations

Entry Information

Gene Name
solute carrier family 27 (fatty acid transporter), member 3
Protein Entry
S27A3_HUMAN
UniProt ID
Q5K4L6
Species
Human

Comments

Comment Type Description
Alternative Products Event=Alternative splicing; Named isoforms=3; Name=1; IsoId=Q5K4L6-1; Sequence=Displayed; Name=2; IsoId=Q5K4L6-2; Sequence=VSP_016218; Name=3; IsoId=Q5K4L6-3; Sequence=VSP_036534, VSP_036535;
Caution It is uncertain whether Met-1 or Met-48 is the initiator.
Function Has acyl-CoA ligase activity for long-chain and very- long-chain fatty acids. Does not exhibit fatty acid transport activity (By similarity).
Sequence Caution Sequence=AAH29792.1; Type=Erroneous initiation; Evidence= ; Sequence=BAB55156.1; Type=Erroneous initiation; Evidence= ; Sequence=BAB84960.1; Type=Erroneous initiation; Evidence= ; Sequence=BAC86050.1; Type=Erroneous initiation; Note=Translation N-terminally extended.; Evidence= ; Sequence=BAC86050.1; Type=Frameshift; Positions=540; Evidence= ; Sequence=CAE12159.1; Type=Erroneous initiation; Evidence= ; Sequence=CAH71420.1; Type=Erroneous initiation; Evidence= ;
Similarity Belongs to the ATP-dependent AMP-binding enzyme family.
Subcellular Location Mitochondrion membrane ; Multi- pass membrane protein .

Identical and Related Proteins

Unique RefSeq proteins for LMP004232 (as displayed in Record Overview)

Protein GI Database Accession Length Protein Name
13236579 RefSeq NP_077306 730 long-chain fatty acid transport protein 3

Identical Sequences to LMP004232 proteins

Reference Database Accession Length Protein Name
GI:13236579 GenBank ABY01530.1 730 Sequence 102 from patent US 7294700
GI:13236579 GenBank ACE31207.1 730 Sequence 102 from patent US 7371836
GI:13236579 GenBank ACN08695.1 730 Sequence 102 from patent US 7488795
GI:13236579 GenBank ADM02098.1 730 Sequence 102 from patent US 7723488
GI:13236579 GenBank AIC50781.1 730 SLC27A3, partial [synthetic construct]
GI:13236579 SwissProt Q5K4L6.3 730 RecName: Full=Long-chain fatty acid transport protein 3; Short=FATP-3; Short=Fatty acid transport protein 3; AltName: Full=Solute carrier family 27 member 3; AltName: Full=Very long-chain acyl-CoA synthetase homolog 3; Short=VLCS-3 [Homo sapiens]

Related Sequences to LMP004232 proteins

Reference Database Accession Length Protein Name
GI:13236579 EMBL CAE12159.1 811 very long-chain acyl-CoA synthetase homologue 3 [Homo sapiens]
GI:13236579 GenBank EAW53277.1 811 solute carrier family 27 (fatty acid transporter), member 3, isoform CRA_d [Homo sapiens]
GI:13236579 GenBank JAA08648.1 730 solute carrier family 27 (fatty acid transporter), member 3 [Pan troglodytes]
GI:13236579 GenBank JAA23102.1 730 solute carrier family 27 (fatty acid transporter), member 3 [Pan troglodytes]
GI:13236579 GenBank JAA34478.1 730 solute carrier family 27 (fatty acid transporter), member 3 [Pan troglodytes]
GI:13236579 RefSeq XP_004026808.1 730 PREDICTED: long-chain fatty acid transport protein 3 [Gorilla gorilla gorilla]