Gene/Proteome Database (LMPD)
LMPD ID
LMP004241
Gene ID
Species
Mus musculus (Mouse)
Gene Name
UDP glucuronosyltransferase 1 family, polypeptide A9
Gene Symbol
Synonyms
UDPGT; UDPGT 1-9; UGT1-09; UGT1.9; UGTP4; Ugt1a12; mUGTBr/P
Alternate Names
UDP-glucuronosyltransferase 1-9; UDP-glucuronosyltransferase 1-7; UDP-glucuronosyltransferase 1A9; UDP glycosyltransferase 1 family polypeptide A12
Chromosome
1
Map Location
1 D|1
EC Number
2.4.1.17
Proteins
| UDP-glucuronosyltransferase 1-9 precursor | |
|---|---|
| Refseq ID | NP_964006 |
| Protein GI | 145864463 |
| UniProt ID | Q62452 |
| mRNA ID | NM_201644 |
| Length | 528 |
| RefSeq Status | VALIDATED |
| MAPVAFPTSFFLCLLLASGLAQAGRLLVVPMDGSHWFTMQMVVEKLIHRGHEVVVVIPEVSWQLGKSLNCTVKTYSISHTLEDLDREFKYLSYTQWKTPEHSIRSFLTGSARGFFELTFSHCRSLFNDKKLVEYLKQRFFDAVFLDPFDVCGLIVAKYFSLPSVIFARGVFCDYLEEGAQCPSLPSYVPRLFSKYTDTMTFKERVWNHLIYIEEHAFCSYFLRTAVEVASEILQTPVTMTDLFSPVSIWLLRTDFVLEFPRPVMPNMVFIGGINCLQKKSLSKEFEAYVNASGEHGIVVFSLGSMVSEIPEKKAMEIAEALGRIPQTVLWRYTGTRPSNLAKNTILVKWLPQNDLLGHPKTRAFITHSGSHGIYEGICNGVPMVMMPLFGDQMDNAKRMETRGAGVTLNVLEMTADDLENALKTVINNKSYKENIMRLSSLHKDRPIEPLDLAVFWVEYVMRHKGAPHLRPAAHDLTWYQYHSLDVIGFLLAIVLTVVFIVFKCCAYGCRKCFGGKGRVKKSHKSKTH | |
| sig_peptide: 1..23 inference: COORDINATES: ab initio prediction:SignalP:4.0 calculated_mol_wt: 2369 peptide sequence: MAPVAFPTSFFLCLLLASGLAQA mat_peptide: 24..528 product: UDP-glucuronosyltransferase 1-9 experiment: experimental evidence, no additional details recorded note: propagated from UniProtKB/Swiss-Prot (Q62452.3) calculated_mol_wt: 57657 peptide sequence: GRLLVVPMDGSHWFTMQMVVEKLIHRGHEVVVVIPEVSWQLGKSLNCTVKTYSISHTLEDLDREFKYLSYTQWKTPEHSIRSFLTGSARGFFELTFSHCRSLFNDKKLVEYLKQRFFDAVFLDPFDVCGLIVAKYFSLPSVIFARGVFCDYLEEGAQCPSLPSYVPRLFSKYTDTMTFKERVWNHLIYIEEHAFCSYFLRTAVEVASEILQTPVTMTDLFSPVSIWLLRTDFVLEFPRPVMPNMVFIGGINCLQKKSLSKEFEAYVNASGEHGIVVFSLGSMVSEIPEKKAMEIAEALGRIPQTVLWRYTGTRPSNLAKNTILVKWLPQNDLLGHPKTRAFITHSGSHGIYEGICNGVPMVMMPLFGDQMDNAKRMETRGAGVTLNVLEMTADDLENALKTVINNKSYKENIMRLSSLHKDRPIEPLDLAVFWVEYVMRHKGAPHLRPAAHDLTWYQYHSLDVIGFLLAIVLTVVFIVFKCCAYGCRKCFGGKGRVKKSHKSKTH | |
Gene Information
Entrez Gene ID
Gene Name
UDP glucuronosyltransferase 1 family, polypeptide A9
Gene Symbol
Species
Mus musculus
Gene Ontology (GO Annotations)
| GO ID | Source | Type | Description |
|---|---|---|---|
| GO:0005783 | IEA:UniProtKB-KW | C | endoplasmic reticulum |
| GO:0016021 | IEA:UniProtKB-KW | C | integral component of membrane |
| GO:0015020 | IEA:UniProtKB-EC | F | glucuronosyltransferase activity |
KEGG Pathway Links
Domain Information
InterPro Annotations
| Accession | Description |
|---|---|
| IPR002213 | UDP-glucuronosyl/UDP-glucosyltransferase |
UniProt Annotations
Entry Information
Gene Name
UDP glucuronosyltransferase 1 family, polypeptide A9
Protein Entry
UD19_MOUSE
UniProt ID
Species
Mouse
Comments
| Comment Type | Description |
|---|---|
| Alternative Products | Event=Alternative splicing; Named isoforms=1; Comment=A number of isoforms may be produced. Isoforms have a different N-terminal domain and a common C-terminal domain of 245 residues.; Name=1; IsoId=Q62452-1; Sequence=Displayed; |
| Catalytic Activity | UDP-glucuronate + acceptor = UDP + acceptor beta-D-glucuronoside. |
| Function | UDPGT is of major importance in the conjugation and subsequent elimination of potentially toxic xenobiotics and endogenous compounds. |
| Sequence Caution | Sequence=AAA40524.1; Type=Erroneous initiation; Note=Translation N-terminally extended.; Evidence={ECO:0000305}; |
| Similarity | Belongs to the UDP-glycosyltransferase family. {ECO:0000305}. |
| Subcellular Location | Microsome. Endoplasmic reticulum membrane {ECO:0000305}; Single-pass membrane protein {ECO:0000305}. |
| Tissue Specificity | Highly expressed in liver and at lower levels in stomach and kidney. {ECO:0000269|PubMed:14672974}. |
Identical and Related Proteins
Unique RefSeq proteins for LMP004241 (as displayed in Record Overview)
| Protein GI | Database | Accession | Length | Protein Name |
|---|---|---|---|---|
| 145864463 | RefSeq | NP_964006 | 528 | UDP-glucuronosyltransferase 1-9 precursor |
Identical Sequences to LMP004241 proteins
| Reference | Database | Accession | Length | Protein Name |
|---|---|---|---|---|
| GI:145864463 | SwissProt | Q62452.3 | 528 | RecName: Full=UDP-glucuronosyltransferase 1-9; Short=UDPGT 1-9; Short=UGT1*9; Short=UGT1-09; Short=UGT1.9; AltName: Full=UDP-glucuronosyltransferase 1-7; Short=UDPGT; AltName: Full=UDP-glucuronosyltransferase 1A9; AltName: Full=UGT1A12; AltName: Full=UGTP4; Flags: Precursor [Mus musculus] |
Related Sequences to LMP004241 proteins
| Reference | Database | Accession | Length | Protein Name |
|---|---|---|---|---|
| GI:145864463 | GenBank | AAA40524.1 | 498 | bilirubin/phenol UDP-glucuronosyltransferase [Mus musculus domesticus] |
| GI:145864463 | GenBank | AAP48599.1 | 528 | UDP glycosyltransferase 1 family polypeptide A12 [Mus musculus] |
| GI:145864463 | GenBank | EDL40126.1 | 498 | mCG14318, isoform CRA_f [Mus musculus] |
| GI:145864463 | GenBank | AAI46022.1 | 528 | UDP glucuronosyltransferase 1 family, polypeptide A9 [Mus musculus] |
| GI:145864463 | GenBank | AAI38700.1 | 528 | UDP glucuronosyltransferase 1 family, polypeptide A9 [Mus musculus] |
| GI:145864463 | RefSeq | NP_964003.2 | 530 | UDP glycosyltransferase 1 family, polypeptide A10 precursor [Mus musculus] |