Gene/Proteome Database (LMPD)

LMPD ID
LMP004322
Gene ID
208211
Species
Mus musculus (Mouse)
Gene Name
asparagine-linked glycosylation 1 (beta-1,4-mannosyltransferase)
Gene Symbol
Alg1
Synonyms
HMAT1; HMT1
Alternate Names
chitobiosyldiphosphodolichol beta-mannosyltransferase; beta-1,4 mannosyltransferase; beta-1,4-mannosyltransferase; GDP-Man:GlcNAc2-PP-dolichol mannosyltransferase; asparagine-linked glycosylation protein 1 homolog; GDP-mannose-dolichol diphosphochitobiose mannosyltransferase; asparagine-linked glycosylation 1 homolog (yeast, beta-1,4-mannosyltransferase)
Chromosome
16
Map Location
16 A1|16
EC Number
2.4.1.142

Proteins

chitobiosyldiphosphodolichol beta-mannosyltransferase
Refseq ID NP_663337
Protein GI 148277043
UniProt ID Q921Q3
mRNA ID NM_145362
Length 482
RefSeq Status VALIDATED
MAASCVALLVLALLLLVLLLGLWKRGRQTGRARHMVVVVLGDVGRSPRMQYHALSLAQSGFSVTLLGFYNSKPRDELLQNDRIRIVKLTDLRGLGAGPRILQYGVKVVFQAVYLLWKMMRMDPAAYIFLQNPPGLPAIAVCWFVGCICGSKLVIDWHNYGYSIMGLVHGPRHPIVLLAKWYEKFFGRLSHLNLCVTNAMREDLAENWCVRAVTLYDKPASFFKETPLDLQHELFMKLSHTYSPFQSCSDPSHPDTERSAFTERDCQSGVVRRLHGRPALLVSSTSWTEDEDFSILLRALEKFEQQALTGDSLPSLVCVITGKGPLREHYRHLISQKHLQHVRFCTPWLEAEDYPLLLGSADLGVCLHMSSSGLDLPMKVVDMFGCHLPVCAVNFKCLHELVRHGENGLVFKDAEELAAQLQMLFSKFPDPAGKLSQFRKKLQESGQQRWDESWQHTVLPLLAHSQMTPRPHPPCGHPSCRGF

Gene Information

Entrez Gene ID
208211
Gene Name
asparagine-linked glycosylation 1 (beta-1,4-mannosyltransferase)
Gene Symbol
Alg1
Species
Mus musculus

Gene Ontology (GO Annotations)

GO ID Source Type Description
GO:0005783 IEA:UniProtKB-KW C endoplasmic reticulum
GO:0016021 IEA:UniProtKB-KW C integral component of membrane
GO:0004578 IEA:UniProtKB-EC F chitobiosyldiphosphodolichol beta-mannosyltransferase activity
GO:0006486 IEA:UniProtKB-UniPathway P protein glycosylation

KEGG Pathway Links

KEGG Pathway ID Description
mmu01100 Metabolic pathways
ko00510 N-Glycan biosynthesis
mmu00510 N-Glycan biosynthesis

Domain Information

InterPro Annotations

Accession Description
IPR026051 Asparagine-linked glycosylation protein 1-like

UniProt Annotations

Entry Information

Gene Name
asparagine-linked glycosylation 1 (beta-1,4-mannosyltransferase)
Protein Entry
ALG1_MOUSE
UniProt ID
Q921Q3
Species
Mouse

Comments

Comment Type Description
Alternative Products Event=Alternative splicing; Named isoforms=2; Name=1; IsoId=Q921Q3-1; Sequence=Displayed; Name=2; IsoId=Q921Q3-2; Sequence=VSP_032516;
Catalytic Activity GDP-mannose + chitobiosyldiphosphodolichol = GDP + beta-1,4-D-mannosylchitobiosyldiphosphodolichol.
Function Participates in the formation of the lipid-linked precursor oligosaccharide for N-glycosylation. Involved in assembling the dolichol-pyrophosphate-GlcNAc(2)-Man(5) intermediate on the cytoplasmic surface of the ER (By similarity). {ECO:0000250}.
Pathway Protein modification; protein glycosylation.
Sequence Caution Sequence=BC011281; Type=Frameshift; Positions=462; Evidence={ECO:0000305};
Similarity Belongs to the glycosyltransferase group 1 family. Glycosyltransferase 33 subfamily. {ECO:0000305}.
Subcellular Location Endoplasmic reticulum membrane {ECO:0000250}; Single-pass type II membrane protein {ECO:0000250}.

Identical and Related Proteins

Unique RefSeq proteins for LMP004322 (as displayed in Record Overview)

Protein GI Database Accession Length Protein Name
148277043 RefSeq NP_663337 482 chitobiosyldiphosphodolichol beta-mannosyltransferase

Identical Sequences to LMP004322 proteins

Reference Database Accession Length Protein Name
GI:148277043 DBBJ BAE26713.1 482 unnamed protein product [Mus musculus]
GI:148277043 SwissProt Q921Q3.3 482 RecName: Full=Chitobiosyldiphosphodolichol beta-mannosyltransferase; AltName: Full=Asparagine-linked glycosylation protein 1 homolog; AltName: Full=Beta-1,4-mannosyltransferase; AltName: Full=GDP-Man:GlcNAc2-PP-dolichol mannosyltransferase; AltName: Full=GDP-mannose-dolichol diphosphochitobiose mannosyltransferase [Mus musculus]

Related Sequences to LMP004322 proteins

Reference Database Accession Length Protein Name
GI:148277043 GenBank EDK97283.1 460 asparagine-linked glycosylation 1 homolog (yeast, beta-1,4-mannosyltransferase), isoform CRA_a, partial [Mus musculus]
GI:148277043 GenBank EDK97284.1 510 asparagine-linked glycosylation 1 homolog (yeast, beta-1,4-mannosyltransferase), isoform CRA_b [Mus musculus]
GI:148277043 RefSeq XP_005081815.1 464 PREDICTED: chitobiosyldiphosphodolichol beta-mannosyltransferase [Mesocricetus auratus]
GI:148277043 RefSeq XP_005349334.1 464 PREDICTED: chitobiosyldiphosphodolichol beta-mannosyltransferase [Microtus ochrogaster]
GI:148277043 RefSeq XP_006245864.1 465 PREDICTED: chitobiosyldiphosphodolichol beta-mannosyltransferase isoform X1 [Rattus norvegicus]
GI:148277043 RefSeq XP_006984724.1 470 PREDICTED: chitobiosyldiphosphodolichol beta-mannosyltransferase [Peromyscus maniculatus bairdii]