Gene/Proteome Database (LMPD)

LMPD ID
LMP004348
Gene ID
100340
Species
Mus musculus (Mouse)
Gene Name
sphingomyelin phosphodiesterase, acid-like 3B
Gene Symbol
Smpdl3b
Synonyms
1110054A24Rik; AU045240; Asml3b
Alternate Names
acid sphingomyelinase-like phosphodiesterase 3b; ASM-like phosphodiesterase 3b
Chromosome
4
Map Location
4 D2.3|4
EC Number
3.1.4.-

Proteins

acid sphingomyelinase-like phosphodiesterase 3b precursor
Refseq ID NP_598649
Protein GI 19527104
UniProt ID P58242
mRNA ID NM_133888
Length 456
RefSeq Status PROVISIONAL
MTLLGWLIFLAPWGVAGAQLGRFWHISDLHLDPNYTVSKDPLQVCPSAGSQPVLNAGPWGDYLCDSPWALINSSLYAMKEIEPKPDFILWTGDDTPHVPNESLGEAAVLAIVERLTNLIKEVFPDTKVYAALGNHDFHPKNQFPAQSNRIYNQVAELWRPWLSNESYALFKRGAFYSEKLPGPSRAGRVVVLNTNLYYSNNEQTAGMADPGEQFRWLGDVLSNASRDGEMVYVIGHVPPGFFEKTQNKAWFRESFNEEYLKVIQKHHRVIAGQFFGHHHTDSFRMFYDNTGAPINVMFLTPGVTPWKTTLPGVVDGANNPGIRIFEYDRATLNLKDLVTYFLNLRQANVQETPRWEQEYRLTEAYQVPDASVSSMHTALTRIASEPHILQRYYVYNSVSYNHLTCEDSCRIEHVCAIQHVAFNTYATCLHGLGAKLVPGFLLILTLLPSLHVLEVL
sig_peptide: 1..18 inference: COORDINATES: ab initio prediction:SignalP:4.0 calculated_mol_wt: 1916 peptide sequence: MTLLGWLIFLAPWGVAGA mat_peptide: 19..456 product: Acid sphingomyelinase-like phosphodiesterase 3b experiment: experimental evidence, no additional details recorded note: propagated from UniProtKB/Swiss-Prot (P58242.1) calculated_mol_wt: 49702 peptide sequence: QLGRFWHISDLHLDPNYTVSKDPLQVCPSAGSQPVLNAGPWGDYLCDSPWALINSSLYAMKEIEPKPDFILWTGDDTPHVPNESLGEAAVLAIVERLTNLIKEVFPDTKVYAALGNHDFHPKNQFPAQSNRIYNQVAELWRPWLSNESYALFKRGAFYSEKLPGPSRAGRVVVLNTNLYYSNNEQTAGMADPGEQFRWLGDVLSNASRDGEMVYVIGHVPPGFFEKTQNKAWFRESFNEEYLKVIQKHHRVIAGQFFGHHHTDSFRMFYDNTGAPINVMFLTPGVTPWKTTLPGVVDGANNPGIRIFEYDRATLNLKDLVTYFLNLRQANVQETPRWEQEYRLTEAYQVPDASVSSMHTALTRIASEPHILQRYYVYNSVSYNHLTCEDSCRIEHVCAIQHVAFNTYATCLHGLGAKLVPGFLLILTLLPSLHVLEVL

Gene Information

Entrez Gene ID
100340
Gene Name
sphingomyelin phosphodiesterase, acid-like 3B
Gene Symbol
Smpdl3b
Species
Mus musculus

Gene Ontology (GO Annotations)

GO ID Source Type Description
GO:0005615 IEA:Ensembl C extracellular space
GO:0070062 IEA:Ensembl C extracellular vesicular exosome
GO:0016798 IEA:UniProtKB-KW F hydrolase activity, acting on glycosyl bonds
GO:0004767 IEA:InterPro F sphingomyelin phosphodiesterase activity
GO:0006685 IEA:InterPro P sphingomyelin catabolic process

Domain Information

InterPro Annotations

Accession Description
IPR017064 Acid sphingomyelinase-like phosphodiesterase, predicted
IPR004843 Calcineurin-like phosphoesterase domain, apaH type
IPR029052 Metallo-dependent phosphatase-like

UniProt Annotations

Entry Information

Gene Name
sphingomyelin phosphodiesterase, acid-like 3B
Protein Entry
ASM3B_MOUSE
UniProt ID
P58242
Species
Mouse

Comments

Comment Type Description
Similarity Belongs to the acid sphingomyelinase family. {ECO:0000305}.
Subcellular Location Secreted {ECO:0000250}.

Identical and Related Proteins

Unique RefSeq proteins for LMP004348 (as displayed in Record Overview)

Protein GI Database Accession Length Protein Name
19527104 RefSeq NP_598649 456 acid sphingomyelinase-like phosphodiesterase 3b precursor

Identical Sequences to LMP004348 proteins

Reference Database Accession Length Protein Name
GI:19527104 DBBJ BAE38663.1 456 unnamed protein product [Mus musculus]
GI:19527104 DBBJ BAE32702.1 456 unnamed protein product [Mus musculus]
GI:19527104 GenBank AAH09087.1 456 Sphingomyelin phosphodiesterase, acid-like 3B [Mus musculus]
GI:19527104 SwissProt P58242.1 456 RecName: Full=Acid sphingomyelinase-like phosphodiesterase 3b; Short=ASM-like phosphodiesterase 3b; Flags: Precursor [Mus musculus]

Related Sequences to LMP004348 proteins

Reference Database Accession Length Protein Name
GI:19527104 GenBank AAH97983.1 456 Sphingomyelin phosphodiesterase, acid-like 3B [Rattus norvegicus]
GI:19527104 GenBank EDL30092.1 468 sphingomyelin phosphodiesterase, acid-like 3B [Mus musculus]
GI:19527104 RefSeq NP_001020908.1 456 acid sphingomyelinase-like phosphodiesterase 3b precursor [Rattus norvegicus]
GI:19527104 RefSeq XP_006975664.1 456 PREDICTED: acid sphingomyelinase-like phosphodiesterase 3b [Peromyscus maniculatus bairdii]
GI:19527104 RefSeq XP_003498434.2 460 PREDICTED: acid sphingomyelinase-like phosphodiesterase 3b [Cricetulus griseus]
GI:19527104 RefSeq XP_007634547.1 460 PREDICTED: acid sphingomyelinase-like phosphodiesterase 3b [Cricetulus griseus]