Gene/Proteome Database (LMPD)

LMPD ID
LMP004538
Gene ID
55268
Species
Homo sapiens (Human)
Gene Name
enoyl CoA hydratase domain containing 2
Gene Symbol
ECHDC2
Synonyms
-
Chromosome
1
Map Location
1p32.3

Proteins

enoyl-CoA hydratase domain-containing protein 2, mitochondrial isoform 1
Refseq ID NP_001185890
Protein GI 312176384
UniProt ID Q86YB7
mRNA ID NM_001198961
Length 292
RefSeq Status VALIDATED
MLRVLCLLRPWRPLRARGCASDGAAGGSEIQVRALAGPDQGITEILMNRPSARNALGNVFVSELLETLAQLREDRQVRVLLFRSGVKGVFCAGADLKEREQMSEAEVGVFVQRLRGLMNDIAAFPAPTIAAMDGFALGGGLELALACDLRVAASSAVMGLIETTRGLLPGAGGTQRLPRCLGVALAKELIFTGRRLSGTEAHVLGLVNHAVAQNEEGDAAYQRARALAQEILPQAPIAVRLGKVAIDRGTEVDIASGMAIEGMCYAQNIPTRDRLEGMAAFREKRTPKFVGK
enoyl-CoA hydratase domain-containing protein 2, mitochondrial isoform 2
Refseq ID NP_060751
Protein GI 150378541
UniProt ID Q86YB7
mRNA ID NM_018281
Length 261
RefSeq Status VALIDATED
MLRVLCLLRPWRPLRARGCASDGAAGGSEIQVRALAGPDQGITEILMNRPSARNALGNVFVSELLETLAQLREDRQVRVLLFRSGVKGVFCAGADLKEREQMSEAEVGVFVQRLRGLMNDIASSAVMGLIETTRGLLPGAGGTQRLPRCLGVALAKELIFTGRRLSGTEAHVLGLVNHAVAQNEEGDAAYQRARALAQEILPQAPIAVRLGKVAIDRGTEVDIASGMAIEGMCYAQNIPTRDRLEGMAAFREKRTPKFVGK
transit_peptide: 1..35 inference: non-experimental evidence, no additional details recorded note: Mitochondrion (Potential); propagated from UniProtKB/Swiss-Prot (Q86YB7.2) calculated_mol_wt: 3794 peptide sequence: MLRVLCLLRPWRPLRARGCASDGAAGGSEIQVRAL mat_peptide: 36..292 product: Enoyl-CoA hydratase domain-containing protein 2, mitochondrial experiment: experimental evidence, no additional details recorded note: propagated from UniProtKB/Swiss-Prot (Q86YB7.2) calculated_mol_wt: 27351 peptide sequence: AGPDQGITEILMNRPSARNALGNVFVSELLETLAQLREDRQVRVLLFRSGVKGVFCAGADLKEREQMSEAEVGVFVQRLRGLMNDIAAFPAPTIAAMDGFALGGGLELALACDLRVAASSAVMGLIETTRGLLPGAGGTQRLPRCLGVALAKELIFTGRRLSGTEAHVLGLVNHAVAQNEEGDAAYQRARALAQEILPQAPIAVRLGKVAIDRGTEVDIASGMAIEGMCYAQNIPTRDRLEGMAAFREKRTPKFVGK
enoyl-CoA hydratase domain-containing protein 2, mitochondrial isoform 3
Refseq ID NP_001185891
Protein GI 312222759
UniProt ID F6RJU0
mRNA ID NM_001198962
Length 244
RefSeq Status VALIDATED
MLRVLCLLRPWRPLRARGCASDGAAGGSEIQVRALAGPDQGITEILMNRPSARNALGNVFVSELLETLAQLREDRQVRVLLFRSGVKGVFCAGADLKEREQMSEAEVGVFVQRLRGLMNDIASSAVMGLIETTRGLLPGAGGTQRLPRCLGVALAKELIFTGRRLSGTEAHVLGLVNHAVAQNEEGDAAYQRARALAQEILPQVDIASGMAIEGMCYAQNIPTRDRLEGMAAFREKRTPKFVGK

Gene Information

Entrez Gene ID
55268
Gene Name
enoyl CoA hydratase domain containing 2
Gene Symbol
ECHDC2
Species
Homo sapiens

Gene Ontology (GO Annotations)

GO ID Source Type Description
GO:0005739 IEA:UniProtKB-KW C mitochondrion
GO:0016829 IEA:UniProtKB-KW F lyase activity
GO:0006631 IEA:UniProtKB-KW P fatty acid metabolic process

Domain Information

InterPro Annotations

Accession Description
IPR029045 ClpP/crotonase-like domain
IPR014748 Crontonase, C-terminal
IPR001753 Crotonase_core_superfam
IPR018376 Enoyl-CoA hydratase/isomerase, conserved site

UniProt Annotations

Entry Information

Gene Name
enoyl CoA hydratase domain containing 2
Protein Entry
ECHD2_HUMAN
UniProt ID
Q86YB7
Species
Human

Comments

Comment Type Description
Alternative Products Event=Alternative splicing; Named isoforms=2; Name=1; IsoId=Q86YB7-1; Sequence=Displayed; Name=2; IsoId=Q86YB7-2; Sequence=VSP_029177;
Similarity Belongs to the enoyl-CoA hydratase/isomerase family.
Subcellular Location Mitochondrion .

Identical and Related Proteins

Unique RefSeq proteins for LMP004538 (as displayed in Record Overview)

Protein GI Database Accession Length Protein Name
312176384 RefSeq NP_001185890 292 enoyl-CoA hydratase domain-containing protein 2, mitochondrial isoform 1
150378541 RefSeq NP_060751 261 enoyl-CoA hydratase domain-containing protein 2, mitochondrial isoform 2
312222759 RefSeq NP_001185891 244 enoyl-CoA hydratase domain-containing protein 2, mitochondrial isoform 3

Identical Sequences to LMP004538 proteins

Reference Database Accession Length Protein Name
GI:150378541 GenBank EAX06763.1 261 enoyl Coenzyme A hydratase domain containing 2, isoform CRA_a [Homo sapiens]
GI:312176384 GenBank EAX06767.1 292 enoyl Coenzyme A hydratase domain containing 2, isoform CRA_e [Homo sapiens]
GI:150378541 GenBank EAX06768.1 261 enoyl Coenzyme A hydratase domain containing 2, isoform CRA_a [Homo sapiens]
GI:312176384 GenBank ACE20642.1 292 Sequence 5873 from patent US 7368531
GI:312176384 GenBank ACH31393.1 292 Sequence 5873 from patent US 7411051
GI:312222759 RefSeq XP_003815075.1 244 PREDICTED: enoyl-CoA hydratase domain-containing protein 2, mitochondrial isoform X5 [Pan paniscus]
GI:312176384 SwissProt Q86YB7.2 292 RecName: Full=Enoyl-CoA hydratase domain-containing protein 2, mitochondrial; Flags: Precursor [Homo sapiens]

Related Sequences to LMP004538 proteins

Reference Database Accession Length Protein Name
GI:150378541 DBBJ BAA91922.1 261 unnamed protein product [Homo sapiens]
GI:312176384 GenBank AAH44574.1 292 ECHDC2 protein [Homo sapiens]
GI:312222759 GenBank EAX06763.1 261 enoyl Coenzyme A hydratase domain containing 2, isoform CRA_a [Homo sapiens]
GI:312222759 GenBank EAX06768.1 261 enoyl Coenzyme A hydratase domain containing 2, isoform CRA_a [Homo sapiens]
GI:312176384 GenBank ADQ32500.1 292 enoyl Coenzyme A hydratase domain containing 2, partial [synthetic construct]
GI:312176384 GenBank JAA10639.1 292 enoyl CoA hydratase domain containing 2 [Pan troglodytes]
GI:150378541 GenBank JAA10640.1 261 enoyl CoA hydratase domain containing 2 [Pan troglodytes]
GI:312222759 GenBank JAA18425.1 261 enoyl CoA hydratase domain containing 2 [Pan troglodytes]
GI:150378541 GenBank JAA18425.1 261 enoyl CoA hydratase domain containing 2 [Pan troglodytes]
GI:312176384 GenBank JAA23848.1 292 enoyl CoA hydratase domain containing 2 [Pan troglodytes]
GI:312222759 GenBank JAA23849.1 261 enoyl CoA hydratase domain containing 2 [Pan troglodytes]
GI:150378541 GenBank JAA23849.1 261 enoyl CoA hydratase domain containing 2 [Pan troglodytes]
GI:150378541 GenBank JAA37704.1 261 enoyl CoA hydratase domain containing 2 [Pan troglodytes]
GI:312176384 GenBank AIC56656.1 292 ECHDC2, partial [synthetic construct]
GI:312222759 RefSeq NP_060751.2 261 enoyl-CoA hydratase domain-containing protein 2, mitochondrial isoform 2 [Homo sapiens]
GI:312222759 RefSeq XP_003775736.1 244 PREDICTED: enoyl-CoA hydratase domain-containing protein 2, mitochondrial isoform X4 [Pongo abelii]
GI:150378541 RefSeq XP_003815074.1 261 PREDICTED: enoyl-CoA hydratase domain-containing protein 2, mitochondrial isoform X3 [Pan paniscus]
GI:312176384 RefSeq XP_009456196.1 292 PREDICTED: enoyl-CoA hydratase domain-containing protein 2, mitochondrial [Pan troglodytes]