Gene/Proteome Database (LMPD)

LMPD ID
LMP004550
Gene ID
13480
Species
Mus musculus (Mouse)
Gene Name
dolichol-phosphate (beta-D) mannosyltransferase 1
Gene Symbol
Dpm1
Synonyms
AI118379; AI194292
Alternate Names
dolichol-phosphate mannosyltransferase subunit 1; MPD synthase; DPM synthase subunit 1; mannose-P-dolichol synthase subunit 1; dolichol-phosphate mannose synthase subunit 1; dolichyl-phosphate beta-D-mannosyltransferase subunit 1
Chromosome
2
Map Location
2 H3|2
EC Number
2.4.1.83

Proteins

dolichol-phosphate mannosyltransferase subunit 1
Refseq ID NP_034202
Protein GI 6753670
UniProt ID O70152
mRNA ID NM_010072
Length 260
RefSeq Status VALIDATED
MASTGASRSLAASPRPPQGRSSRQDKYSVLLPTYNERENLPLIVWLLVKSFSESAINYEIIIIDDGSPDGTREVAEQLAEIYGPDRILLRPREKKLGLGTAYIHGIKHATGNYVIIMDADLSHHPKFIPEFIRKQKEGNFDIVSGTRYKGNGGVYGWDLKRKIISRGANFITQILLRPGASDLTGSFRLYRKEVLQKLIEKCVSKGYVFQMEMIVRARQMNYTIGEVPISFVDRVYGESKLGGNEIVSFLKGLLTLFATT

Gene Information

Entrez Gene ID
13480
Gene Name
dolichol-phosphate (beta-D) mannosyltransferase 1
Gene Symbol
Dpm1
Species
Mus musculus

Gene Ontology (GO Annotations)

GO ID Source Type Description
GO:0005789 ISS:HGNC C endoplasmic reticulum membrane
GO:0004582 ISS:HGNC F dolichyl-phosphate beta-D-mannosyltransferase activity
GO:0004169 ISS:HGNC F dolichyl-phosphate-mannose-protein mannosyltransferase activity
GO:0006506 ISS:HGNC P GPI anchor biosynthetic process
GO:0035269 ISS:HGNC P protein O-linked mannosylation
GO:0035268 ISS:HGNC P protein mannosylation

KEGG Pathway Links

KEGG Pathway ID Description
mmu01100 Metabolic pathways
ko00510 N-Glycan biosynthesis
mmu00510 N-Glycan biosynthesis

REACTOME Pathway Links

REACTOME Pathway ID Description
5893246 Synthesis of dolichyl-phosphate mannose

Domain Information

InterPro Annotations

Accession Description
IPR001173 Glycosyltransferase 2-like
IPR029044 Nucleotide-diphospho-sugar transferases

UniProt Annotations

Entry Information

Gene Name
dolichol-phosphate (beta-D) mannosyltransferase 1
Protein Entry
DPM1_MOUSE
UniProt ID
O70152
Species
Mouse

Comments

Comment Type Description
Catalytic Activity GDP-mannose + dolichyl phosphate = GDP + dolichyl D-mannosyl phosphate.
Function Transfers mannose from GDP-mannose to dolichol monophosphate to form dolichol phosphate mannose (Dol-P-Man) which is the mannosyl donor in pathways leading to N-glycosylation, glycosyl phosphatidylinositol membrane anchoring, and O- mannosylation of proteins; catalytic subunit of the dolichol- phosphate mannose (DPM) synthase complex. {ECO:0000250}.
Pathway Protein modification; protein glycosylation.
Similarity Belongs to the glycosyltransferase 2 family. {ECO:0000305}.
Subcellular Location Endoplasmic reticulum.
Subunit Component of the dolichol-phosphate mannose (DPM) synthase complex composed of DPM1, DPM2 and DPM3; in the complex interacts directly with DPM3. {ECO:0000250}.

Identical and Related Proteins

Unique RefSeq proteins for LMP004550 (as displayed in Record Overview)

Protein GI Database Accession Length Protein Name
6753670 RefSeq NP_034202 260 dolichol-phosphate mannosyltransferase subunit 1

Identical Sequences to LMP004550 proteins

Reference Database Accession Length Protein Name
GI:6753670 DBBJ BAA25759.1 260 dolichol-phosphate-mannose synthase [Mus musculus]
GI:6753670 DBBJ BAB23602.1 260 unnamed protein product [Mus musculus]
GI:6753670 DBBJ BAB23920.1 260 unnamed protein product [Mus musculus]
GI:6753670 GenBank AAH61151.1 260 Dolichol-phosphate (beta-D) mannosyltransferase 1 [Mus musculus]
GI:6753670 GenBank EDL06547.1 260 dolichol-phosphate (beta-D) mannosyltransferase 1, isoform CRA_e [Mus musculus]
GI:6753670 SwissProt O70152.1 260 RecName: Full=Dolichol-phosphate mannosyltransferase subunit 1; AltName: Full=Dolichol-phosphate mannose synthase subunit 1; Short=DPM synthase subunit 1; AltName: Full=Dolichyl-phosphate beta-D-mannosyltransferase subunit 1; AltName: Full=Mannose-P-dolichol synthase subunit 1; Short=MPD synthase [Mus musculus]

Related Sequences to LMP004550 proteins

Reference Database Accession Length Protein Name
GI:6753670 DBBJ BAB25735.1 260 unnamed protein product [Mus musculus]
GI:6753670 GenBank EDL96369.1 260 rCG32280, isoform CRA_e [Rattus norvegicus]
GI:6753670 RefSeq NP_001100014.1 260 dolichol-phosphate mannosyltransferase subunit 1 [Rattus norvegicus]
GI:6753670 RefSeq NP_001233614.1 266 dolichol-phosphate mannosyltransferase subunit 1 [Cricetulus griseus]
GI:6753670 RefSeq XP_005074489.1 260 PREDICTED: dolichol-phosphate mannosyltransferase [Mesocricetus auratus]
GI:6753670 SwissProt Q9WU83.1 266 RecName: Full=Dolichol-phosphate mannosyltransferase subunit 1; AltName: Full=Dolichol-phosphate mannose synthase subunit 1; Short=DPM synthase subunit 1; AltName: Full=Dolichyl-phosphate beta-D-mannosyltransferase subunit 1; AltName: Full=Mannose-P-dolichol synthase subunit 1; Short=MPD synthase subunit 1 [Cricetulus griseus]