Gene/Proteome Database (LMPD)

LMPD ID
LMP004782
Gene ID
20917
Species
Mus musculus (Mouse)
Gene Name
succinate-Coenzyme A ligase, GDP-forming, beta subunit
Gene Symbol
Suclg2
Synonyms
AF171077; AW556404; D6Wsu120e; SCS-betaG
Alternate Names
succinyl-CoA ligase [GDP-forming] subunit beta, mitochondrial; succinyl-CoA synthetase beta-G chain; GTP-specific succinyl-CoA synthetase beta subunit
Chromosome
6
Map Location
6 D3|6 44.63 cM
EC Number
6.2.1.4

Proteins

succinyl-CoA ligase [GDP-forming] subunit beta, mitochondrial precursor
Refseq ID NP_035637
Protein GI 165972309
UniProt ID Q9Z2I8
mRNA ID NM_011507
Length 433
RefSeq Status VALIDATED
MASPVAIAAQAGKLLRERALRPLLAVRSQAGHLTPRRWLNLQEYQSKKLMSEHGVRVQRFFVANTAKEALEAAKRLNAKEIVLKAQILAGGRGKGVFNSGLKGGVHLTKDPKVVGELAQQMIGYNLATKQTPKEGVKVNKVMVAEALDISRETYLAILMDRSHNGPVIVGSPQGGVDIEEVAASSPELIFKEQIDIFEGIKDSQAQRMAENLGFLGSLKNQAADQITKLYHLFLKIDATQVEVNPFGETPEGQVVCFDAKINFDDNAEFRQKDIFAMDDKSENEPIENEAARYDLKYIGLDGNIACFVNGAGLAMATCDIIFLNGGKPANFLDLGGGVKEAQVYEAFKLLTSDPKVEAILVNIFGGIVNCAIIANGITKACRELELKVPLVVRLEGTNVQEAQNILKSSGLPITSAVDLEDAAKKAVASVAKK
transit_peptide: 1..38 inference: non-experimental evidence, no additional details recorded note: Mitochondrion (By similarity); propagated from UniProtKB/Swiss-Prot (Q9Z2I8.3) calculated_mol_wt: 4163 peptide sequence: MASPVAIAAQAGKLLRERALRPLLAVRSQAGHLTPRRW mat_peptide: 39..433 product: Succinyl-CoA ligase [GDP-forming] subunit beta, mitochondrial experiment: experimental evidence, no additional details recorded note: propagated from UniProtKB/Swiss-Prot (Q9Z2I8.3) calculated_mol_wt: 42695 peptide sequence: LNLQEYQSKKLMSEHGVRVQRFFVANTAKEALEAAKRLNAKEIVLKAQILAGGRGKGVFNSGLKGGVHLTKDPKVVGELAQQMIGYNLATKQTPKEGVKVNKVMVAEALDISRETYLAILMDRSHNGPVIVGSPQGGVDIEEVAASSPELIFKEQIDIFEGIKDSQAQRMAENLGFLGSLKNQAADQITKLYHLFLKIDATQVEVNPFGETPEGQVVCFDAKINFDDNAEFRQKDIFAMDDKSENEPIENEAARYDLKYIGLDGNIACFVNGAGLAMATCDIIFLNGGKPANFLDLGGGVKEAQVYEAFKLLTSDPKVEAILVNIFGGIVNCAIIANGITKACRELELKVPLVVRLEGTNVQEAQNILKSSGLPITSAVDLEDAAKKAVASVAKK

Gene Information

Entrez Gene ID
20917
Gene Name
succinate-Coenzyme A ligase, GDP-forming, beta subunit
Gene Symbol
Suclg2
Species
Mus musculus

Gene Ontology (GO Annotations)

GO ID Source Type Description
GO:0005739 IDA:MGI C mitochondrion
GO:0005886 IEA:Ensembl C plasma membrane
GO:0045244 IEA:Ensembl C succinate-CoA ligase complex (GDP-forming)
GO:0005524 IEA:InterPro F ATP binding
GO:0019003 IEA:Ensembl F GDP binding
GO:0005525 IEA:UniProtKB-KW F GTP binding
GO:0046872 IEA:InterPro F metal ion binding
GO:0004776 IEA:UniProtKB-EC F succinate-CoA ligase (GDP-forming) activity
GO:0004777 ISA:MGI F succinate-semialdehyde dehydrogenase (NAD+) activity
GO:0006105 IEA:Ensembl P succinate metabolic process
GO:0006104 IEA:Ensembl P succinyl-CoA metabolic process
GO:0006099 IEA:UniProtKB-UniPathway P tricarboxylic acid cycle

KEGG Pathway Links

KEGG Pathway ID Description
mmu01200 Carbon metabolism
mmu00020 Citrate cycle (TCA cycle)

Domain Information

InterPro Annotations

Accession Description
IPR005811 ATP-citrate lyase/succinyl-CoA ligase
IPR011761 ATP-grasp fold
IPR013815 ATP-grasp fold, subdomain 1
IPR013816 ATP-grasp fold, subdomain 2
IPR013650 ATP-grasp fold, succinyl-CoA synthetase-type
IPR005809 Succinyl-CoA synthetase, beta subunit
IPR017866 Succinyl-CoA synthetase, beta subunit, conserved site
IPR016102 Succinyl-CoA synthetase-like

UniProt Annotations

Entry Information

Gene Name
succinate-Coenzyme A ligase, GDP-forming, beta subunit
Protein Entry
SUCB2_MOUSE
UniProt ID
Q9Z2I8
Species
Mouse

Comments

Comment Type Description
Alternative Products Event=Alternative splicing; Named isoforms=2; Name=1; IsoId=Q9Z2I8-1; Sequence=Displayed; Name=2; IsoId=Q9Z2I8-2; Sequence=VSP_016905; Note=No experimental confirmation available.;
Catalytic Activity GTP + succinate + CoA = GDP + phosphate + succinyl-CoA.
Function Catalyzes the GTP-dependent ligation of succinate and CoA to form succinyl-CoA. {ECO:0000250}.
Pathway Carbohydrate metabolism; tricarboxylic acid cycle.
Similarity Belongs to the succinate/malate CoA ligase beta subunit family. {ECO:0000305}.
Similarity Contains 1 ATP-grasp domain. {ECO:0000255|PROSITE- ProRule:PRU00409}.
Subcellular Location Mitochondrion.
Subunit Heterodimer of an alpha and a beta subunit. {ECO:0000250}.

Identical and Related Proteins

Unique RefSeq proteins for LMP004782 (as displayed in Record Overview)

Protein GI Database Accession Length Protein Name
165972309 RefSeq NP_035637 433 succinyl-CoA ligase [GDP-forming] subunit beta, mitochondrial precursor

Identical Sequences to LMP004782 proteins

Reference Database Accession Length Protein Name
GI:165972309 DBBJ BAE39282.1 433 unnamed protein product [Mus musculus]
GI:165972309 SwissProt Q9Z2I8.3 433 RecName: Full=Succinyl-CoA ligase [GDP-forming] subunit beta, mitochondrial; AltName: Full=GTP-specific succinyl-CoA synthetase subunit beta; AltName: Full=Succinyl-CoA synthetase beta-G chain; Short=SCS-betaG; Flags: Precursor [Mus musculus]

Related Sequences to LMP004782 proteins

Reference Database Accession Length Protein Name
GI:165972309 DBBJ BAE43068.1 433 unnamed protein product [Mus musculus]
GI:165972309 DBBJ BAE43106.1 433 unnamed protein product [Mus musculus]
GI:165972309 GenBank AAH80781.1 433 Succinate-Coenzyme A ligase, GDP-forming, beta subunit [Mus musculus]
GI:165972309 GenBank EDK99345.1 466 mCG127318 [Mus musculus]
GI:165972309 GenBank EDL40839.1 433 mCG49734 [Mus musculus]
GI:165972309 GenBank AAI60886.1 434 Suclg2 protein [Rattus norvegicus]