Gene/Proteome Database (LMPD)

LMPD ID
LMP004818
Gene ID
57295
Species
Mus musculus (Mouse)
Gene Name
isoprenylcysteine carboxyl methyltransferase
Gene Symbol
Icmt
Synonyms
1700008E11Rik; C80758; Gm13095; HSTE14; OTTMUSG00000010406; PPMT; STE14; pcCMT
Chromosome
4
Map Location
4 E2|4

Proteins

protein-S-isoprenylcysteine O-methyltransferase
Refseq ID NP_598549
Protein GI 51317397
UniProt ID Q3U4N2
mRNA ID NM_133788
Length 284
RefSeq Status VALIDATED
MAGCAARVPPGSEARLSLATFLLGASVLALPLLTRAGLQGRTGLALYVAGLNALLLLLYRPPRYQIAIRACFLGFVFGCGVLLSFSQSSWNHFGWYVCSLSLFHYSEYLVTAVNNPKSLSLDSFLLNHSLEYTVAALSSWIEFTLENIFWPELKQITWLSATGLLMVVFGECLRKAAMFTAGSNFNHVVQSEKSDTHTLVTSGVYAWCRHPSYVGWFYWSIGTQVMLCNPICGVVYALTVWRFFRDRTEEEEISLIHFFGEEYLDYKKRVPTGLPFIKGVKVEL

Gene Information

Entrez Gene ID
57295
Gene Name
isoprenylcysteine carboxyl methyltransferase
Gene Symbol
Icmt
Species
Mus musculus

Gene Ontology (GO Annotations)

GO ID Source Type Description
GO:0005783 IEA:Ensembl C endoplasmic reticulum
GO:0016021 IEA:InterPro C integral component of membrane
GO:0008140 IMP:MGI F cAMP response element binding protein binding
GO:0004671 IMP:MGI F protein C-terminal S-isoprenylcysteine carboxyl O-methyltransferase activity
GO:0006481 IMP:MGI P C-terminal protein methylation
GO:0001701 IMP:MGI P in utero embryonic development
GO:0001889 IMP:MGI P liver development
GO:0035264 IMP:MGI P multicellular organism growth
GO:0008284 IMP:MGI P positive regulation of cell proliferation
GO:0008104 IMP:MGI P protein localization
GO:0006479 IMP:MGI P protein methylation
GO:2001141 IMP:GOC P regulation of RNA biosynthetic process
GO:0046578 IGI:MGI P regulation of Ras protein signal transduction

Domain Information

InterPro Annotations

Accession Description
IPR007269 Isoprenylcysteine carboxyl methyltransferase
IPR025770 Protein-S-isoprenylcysteine O-methyltransferase

UniProt Annotations

Entry Information

Gene Name
isoprenylcysteine carboxyl methyltransferase
Protein Entry
ICMT_MOUSE
UniProt ID
Q3U4N2
Species
Mouse

Identical and Related Proteins

Unique RefSeq proteins for LMP004818 (as displayed in Record Overview)

Protein GI Database Accession Length Protein Name
51317397 RefSeq NP_598549 284 protein-S-isoprenylcysteine O-methyltransferase

Identical Sequences to LMP004818 proteins

Reference Database Accession Length Protein Name
GI:51317397 DBBJ BAE32399.1 284 unnamed protein product [Mus musculus]
GI:51317397 GenBank AAI10696.1 284 Icmt protein [Mus musculus]
GI:51317397 GenBank EDL14933.1 284 isoprenylcysteine carboxyl methyltransferase, isoform CRA_a [Mus musculus]

Related Sequences to LMP004818 proteins

Reference Database Accession Length Protein Name
GI:51317397 GenBank EDL81231.1 284 isoprenylcysteine carboxyl methyltransferase [Rattus norvegicus]
GI:51317397 RefSeq NP_579844.2 284 protein-S-isoprenylcysteine O-methyltransferase [Rattus norvegicus]
GI:51317397 RefSeq XP_003471509.1 284 PREDICTED: protein-S-isoprenylcysteine O-methyltransferase [Cavia porcellus]
GI:51317397 RefSeq XP_004657753.1 284 PREDICTED: protein-S-isoprenylcysteine O-methyltransferase [Jaculus jaculus]
GI:51317397 RefSeq XP_005353703.1 284 PREDICTED: protein-S-isoprenylcysteine O-methyltransferase [Microtus ochrogaster]
GI:51317397 RefSeq XP_006993842.1 284 PREDICTED: protein-S-isoprenylcysteine O-methyltransferase [Peromyscus maniculatus bairdii]