Gene/Proteome Database (LMPD)

LMPD ID
LMP004936
Gene ID
283985
Species
Homo sapiens (Human)
Gene Name
fatty acid desaturase 6
Gene Symbol
FADS6
Synonyms
-
Alternate Names
fatty acid desaturase 6; fatty acid desaturase domain family, member 6
Chromosome
17
Map Location
17q25.1
EC Number
1.14.19.-

Proteins

fatty acid desaturase 6
Refseq ID NP_835229
Protein GI 618467106
UniProt ID Q8N9I5
mRNA ID NM_178128
Length 368
RefSeq Status VALIDATED
MEPTEPMEPTEPMEPTEPMEPTEPMEPTEPMEPARSAHRGGEALLRELEVLVQDVVRTSSWWERHGVDCAILALSLFALPAGFLCLRWENALVFASGITILGVCHYTLTVKGSHLATHGALTESKRWSKIWLLFFVEVCTAFTAEHATHGHVKMHHAYTNVVGLGDSSTWRLPCLNRYVYMFLAPFLLPIATPLVAVERLRKVELGTALRTLALISLGLYSHYWLLLNVSGFKNPSSALGCMFLTRSLLAHPYLHVNIFQHIGLPMFSRDNKPRRIHMMSLGVLNLARLPVLDWAFGHSIISCHVEHHLFPRLSDNMCLKVKPVVSQFLREKQLPYNEDSYLARFQLFLRRYEEFMVQAPPITELVGL

Gene Information

Entrez Gene ID
283985
Gene Name
fatty acid desaturase 6
Gene Symbol
FADS6
Species
Homo sapiens

Gene Ontology (GO Annotations)

GO ID Source Type Description
GO:0016021 IEA:UniProtKB-KW C integral component of membrane
GO:0016491 IEA:UniProtKB-KW F oxidoreductase activity
GO:0006633 IEA:UniProtKB-KW P fatty acid biosynthetic process

BIOCYC Pathway Links

BIOCYC Pathway ID Description
PWY-5996 oleate biosynthesis II (animals)

Domain Information

InterPro Annotations

Accession Description
IPR005804 Fatty acid desaturase, type 1

UniProt Annotations

Entry Information

Gene Name
fatty acid desaturase 6
Protein Entry
FADS6_HUMAN
UniProt ID
Q8N9I5
Species
Human

Comments

Comment Type Description
Alternative Products Event=Alternative splicing; Named isoforms=2; Name=1; IsoId=Q8N9I5-1; Sequence=Displayed; Name=2; IsoId=Q8N9I5-2; Sequence=VSP_034320; Note=No experimental confirmation available.;
Pathway Lipid metabolism; fatty acid metabolism.
Sequence Caution Sequence=BAC04349.1; Type=Miscellaneous discrepancy; Note=The N-terminus contains a duplication of the repeated 'MEPTEP' sequence. It is unclear whether such duplication is due to a sequencing error or a polymorphism.; Evidence= ;
Similarity Belongs to the fatty acid desaturase family.
Subcellular Location Membrane ; Multi-pass membrane protein .

Identical and Related Proteins

Unique RefSeq proteins for LMP004936 (as displayed in Record Overview)

Protein GI Database Accession Length Protein Name
618467106 RefSeq NP_835229 368 fatty acid desaturase 6

Identical Sequences to LMP004936 proteins

Reference Database Accession Length Protein Name

Related Sequences to LMP004936 proteins

Reference Database Accession Length Protein Name
GI:618467106 DBBJ BAC04349.1 374 unnamed protein product [Homo sapiens]
GI:618467106 GenBank AAI17231.2 356 FADS6 protein [Homo sapiens]
GI:618467106 GenBank ABP27586.1 374 Sequence 2601 from patent US 7193069
GI:618467106 GenBank AHE02232.1 374 Sequence 60586 from patent US 8586006
GI:618467106 RefSeq XP_005257281.2 382 PREDICTED: fatty acid desaturase 6 isoform X1 [Homo sapiens]
GI:618467106 SwissProt Q8N9I5.2 356 RecName: Full=Fatty acid desaturase 6 [Homo sapiens]