Gene/Proteome Database (LMPD)

LMPD ID
LMP004971
Gene ID
26878
Species
Mus musculus (Mouse)
Gene Name
UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 2
Gene Symbol
B3galt2
Synonyms
-
Alternate Names
beta-1,3-galactosyltransferase 2; beta3GalT2; beta3Gal-T2; beta-1,3-GalTase 2; UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase-II
Chromosome
1
Map Location
1 F|1
EC Number
2.4.1.-

Proteins

beta-1,3-galactosyltransferase 2
Refseq ID NP_064409
Protein GI 157266277
UniProt ID O54905
mRNA ID NM_020025
Length 422
RefSeq Status VALIDATED
MLQWRRRHCCFAKMTWSPKRSLLRTPLTGVLSLVFLFAMFLFFNHHDWLPGRPGFKENPVTYTFRGFRSTKSETNHSSLRTIWKEVAPQTLRPHTASNSSNTELSPQGVTGLQNTLSANGSIYNEKGTGHPNSYHFKYIINEPEKCQEKSPFLILLIAAEPGQIEARRAIRQTWGNETLAPGIQIIRVFLLGISIKLNGYLQHAIQEESRQYHDIIQQEYLDTYYNLTIKTLMGMNWVATYCPHTPYVMKTDSDMFVNTEYLIHKLLKPDLPPRHNYFTGYLMRGYAPNRNKDSKWYMPPDLYPSERYPVFCSGTGYVFSGDLAEKIFKVSLGIRRLHLEDVYVGICLAKLRVDPVPPPNEFVFNHWRVSYSSCKYSHLITSHQFQPSELIKYWNHLQQNKHNACANAAKEKAGRYRHRKLH

Gene Information

Entrez Gene ID
26878
Gene Name
UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 2
Gene Symbol
B3galt2
Species
Mus musculus

Gene Ontology (GO Annotations)

GO ID Source Type Description
GO:0005794 IEA:UniProtKB-KW C Golgi apparatus
GO:0016021 IEA:UniProtKB-KW C integral component of membrane
GO:0008499 IDA:MGI F UDP-galactose:beta-N-acetylglucosamine beta-1,3-galactosyltransferase activity
GO:0009312 IDA:MGI P oligosaccharide biosynthetic process
GO:0006486 IEA:UniProtKB-UniPathway P protein glycosylation

KEGG Pathway Links

KEGG Pathway ID Description
mmu00601 Glycosphingolipid biosynthesis - lacto and neolacto series
M00070 Glycosphingolipid biosynthesis, lacto-series, LacCer => Lc4Cer
mmu01100 Metabolic pathways

Domain Information

InterPro Annotations

Accession Description
IPR002659 Glycosyl transferase, family 31

UniProt Annotations

Entry Information

Gene Name
UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 2
Protein Entry
B3GT2_MOUSE
UniProt ID
O54905
Species
Mouse

Comments

Comment Type Description
Cofactor Name=Mn(2+); Xref=ChEBI:CHEBI:29035; Evidence={ECO:0000269|PubMed:9417047};
Function Beta-1,3-galactosyltransferase that transfers galactose from UDP-galactose to substrates with a terminal beta-N- acetylglucosamine (beta-GlcNAc) residue. Can also utilize substrates with a terminal galactose residue, albeit with lower efficiency. Involved in the biosynthesis of the carbohydrate moieties of glycolipids and glycoproteins. {ECO:0000269|PubMed:9417047}.
Pathway Protein modification; protein glycosylation.
Similarity Belongs to the glycosyltransferase 31 family. {ECO:0000305}.
Subcellular Location Golgi apparatus membrane {ECO:0000305}; Single-pass type II membrane protein {ECO:0000305}.
Tissue Specificity Detected in brain and heart. {ECO:0000269|PubMed:9417047}.
Web Resource Name=Functional Glycomics Gateway - GTase; Note=b3GalT2; URL="http://www.functionalglycomics.org/glycomics/molecule/jsp/glycoEnzyme/viewGlycoEnzyme.jsp?gbpId=gt_mou_455";

Identical and Related Proteins

Unique RefSeq proteins for LMP004971 (as displayed in Record Overview)

Protein GI Database Accession Length Protein Name
157266277 RefSeq NP_064409 422 beta-1,3-galactosyltransferase 2

Identical Sequences to LMP004971 proteins

Reference Database Accession Length Protein Name
GI:157266277 DBBJ BAC29317.1 422 unnamed protein product [Mus musculus]
GI:157266277 DBBJ BAC38793.1 422 unnamed protein product [Mus musculus]
GI:157266277 GenBank AAH46322.1 422 UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 2 [Mus musculus]
GI:157266277 GenBank EDL39516.1 422 mCG19763 [Mus musculus]
GI:157266277 SwissProt O54905.2 422 RecName: Full=Beta-1,3-galactosyltransferase 2; Short=Beta-1,3-GalTase 2; Short=Beta3Gal-T2; Short=Beta3GalT2; AltName: Full=UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase-II [Mus musculus]

Related Sequences to LMP004971 proteins

Reference Database Accession Length Protein Name
GI:157266277 DBBJ BAB68668.1 409 UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase II, partial [Mus musculus domesticus]
GI:157266277 DBBJ BAB68669.1 409 UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase II, partial [Mus musculus brevirostris]
GI:157266277 DBBJ BAB68673.1 409 UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase II, partial [Mus musculus domesticus]
GI:157266277 DBBJ BAC28688.1 422 unnamed protein product [Mus musculus]
GI:157266277 GenBank AAC53524.1 422 UDP-Gal:betaGlcNAc beta 1,3-galactosyltranferase-II [Mus musculus]
GI:157266277 GenBank AED17209.1 422 Sequence 523 from patent US 7879544