Gene/Proteome Database (LMPD)

LMPD ID
LMP005015
Gene ID
55981
Species
Mus musculus (Mouse)
Gene Name
phosphatidylinositol glycan anchor biosynthesis, class B
Gene Symbol
Pigb
Synonyms
Pig-b
Alternate Names
GPI mannosyltransferase 3; GPI-MT-III; GPI mannosyltransferase III; involved in GPI-anchor biosynthesis; phosphatidylinositol glycan, class B; phosphatidylinositol-glycan biosynthesis class B protein
Chromosome
9
Map Location
9 D|9
EC Number
2.4.1.-

Proteins

GPI mannosyltransferase 3
Refseq ID NP_061377
Protein GI 167900468
UniProt ID Q9JJQ0
mRNA ID NM_018889
Length 542
RefSeq Status VALIDATED
MESQAADYNPASRNLHGSSGEMKLRRRKSRQYVSAQEKRSPRRGLLGENTYLVLFTIALRILNCFLVQTSFVPDEYWQSLEVAHRMVFSYGYLTWEWTERLRGYTYPLIFASIYKVLHLLGKDSVQFLIWIPRLGQALLSAVADIRLYSLLKQLENQEVAQWVFLCQLCSWFTWYCCTRTLTNTMETSLTALALFYYPLEGSRSVNSVKYSLLVALACVVRPTALIPWVPLLFRHFYQEQRKLHLTLHHFLPVGFITFSLSLIIDRIFFGQWTLVQLNFLKFNVLQNLGTFYGSHPWHWYLSQGFPVVLGTHLPFFIHGCFLAPRRLHILLLTVLWTLLVYSMLGHKEFRFIYPVLPFCMVFCGYSLAHLKTWRKAALSFLLLSNVPLAFYTGLVHQRGTLDVMNHIQKVCPRGPDPASASVFIMMPCHSTPYYSHVHCPLSMRFLQCPPDLTGKTQYLDEADMFYLNPLRWLQQEFHSNASLPTHLVTFNVLEKEINTFLTSGNYERAATFFHTHWPERRTGSHIHVYERRLPGRVNTGGN

Gene Information

Entrez Gene ID
55981
Gene Name
phosphatidylinositol glycan anchor biosynthesis, class B
Gene Symbol
Pigb
Species
Mus musculus

Gene Ontology (GO Annotations)

GO ID Source Type Description
GO:0005789 IDA:MGI C endoplasmic reticulum membrane
GO:0016021 IEA:UniProtKB-KW C integral component of membrane
GO:0000030 IEA:Ensembl F mannosyltransferase activity
GO:0006506 IEA:UniProtKB-UniPathway P GPI anchor biosynthetic process
GO:0006505 ISS:MGI P GPI anchor metabolic process

KEGG Pathway Links

KEGG Pathway ID Description
mmu00563 Glycosylphosphatidylinositol(GPI)-anchor biosynthesis
mmu01100 Metabolic pathways

REACTOME Pathway Links

REACTOME Pathway ID Description
5893244 Synthesis of glycosylphosphatidylinositol (GPI)

Domain Information

InterPro Annotations

Accession Description
IPR005599 GPI mannosyltransferase

UniProt Annotations

Entry Information

Gene Name
phosphatidylinositol glycan anchor biosynthesis, class B
Protein Entry
PIGB_MOUSE
UniProt ID
Q9JJQ0
Species
Mouse

Comments

Comment Type Description
Function Mannosyltransferase involved in glycosylphosphatidylinositol-anchor biosynthesis. Transfers the third alpha-1,2-mannose to Man2-GlcN-acyl-PI during GPI precursor assembly (By similarity). {ECO:0000250}.
Pathway Glycolipid biosynthesis; glycosylphosphatidylinositol- anchor biosynthesis.
Similarity Belongs to the glycosyltransferase 22 family. PIGB subfamily. {ECO:0000305}.
Subcellular Location Endoplasmic reticulum membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}.

Identical and Related Proteins

Unique RefSeq proteins for LMP005015 (as displayed in Record Overview)

Protein GI Database Accession Length Protein Name
167900468 RefSeq NP_061377 542 GPI mannosyltransferase 3

Identical Sequences to LMP005015 proteins

Reference Database Accession Length Protein Name
GI:167900468 DBBJ BAE32195.1 542 unnamed protein product [Mus musculus]
GI:167900468 SwissProt Q9JJQ0.2 542 RecName: Full=GPI mannosyltransferase 3; AltName: Full=GPI mannosyltransferase III; Short=GPI-MT-III; AltName: Full=Phosphatidylinositol-glycan biosynthesis class B protein; Short=PIG-B [Mus musculus]

Related Sequences to LMP005015 proteins

Reference Database Accession Length Protein Name
GI:167900468 DBBJ BAA94827.1 542 Pig-b [Mus musculus]
GI:167900468 GenBank AAH52658.1 542 Pigb protein [Mus musculus]
GI:167900468 GenBank EDL26282.1 542 phosphatidylinositol glycan anchor biosynthesis, class B, isoform CRA_b [Mus musculus]
GI:167900468 GenBank EDL84114.1 546 phosphatidylinositol glycan, class B (predicted), isoform CRA_c [Rattus norvegicus]
GI:167900468 RefSeq NP_001101636.3 542 GPI mannosyltransferase 3 [Rattus norvegicus]
GI:167900468 RefSeq XP_005073798.1 547 PREDICTED: GPI mannosyltransferase 3 [Mesocricetus auratus]