Gene/Proteome Database (LMPD)

LMPD ID
LMP005223
Gene ID
60525
Species
Mus musculus (Mouse)
Gene Name
acyl-CoA synthetase short-chain family member 2
Gene Symbol
Acss2
Synonyms
1110017C11Rik; ACAS; Acas1; Acas2; AceCS1; Acs1
Alternate Names
acetyl-coenzyme A synthetase, cytoplasmic; ACS; aceCS; acetate--CoA ligase; acyl-activating enzyme; acetyl-CoA synthetase 1; acetyl-Coenzyme A synthetase 1 (AMP forming); acetyl-Coenzyme A synthetase 2 (ADP forming); acetyl-Coenzyme A synthetase 2 (AMP forming)
Chromosome
2
Map Location
2|2 H2
EC Number
6.2.1.1

Proteins

acetyl-coenzyme A synthetase, cytoplasmic
Refseq ID NP_062785
Protein GI 31980996
UniProt ID Q9QXG4
mRNA ID NM_019811
Length 701
RefSeq Status PROVISIONAL
MGLPEERRKSGSGSRAREETGAEGRVRGWSPPPEVRRSAHVPSLQRYRELHRRSVEEPREFWGNIAKEFYWKTACPGPFLQYNFDVTKGKIFTEWMKGATTNICYNVLDRNVHEKKLGDKVAFYWEGNEPGETTKITYRELLVQVCQFSNVLRKQGIQKGDRVAIYMPMILELVVAMLACARLGALHSIVFAGFSAESLCERILDSSCCLLITTDAFYRGEKLVNLKELADESLEKCREKGFPVRCCIVVKHLGRAELGMNDSPSQSPPVKRPCPDVQICWNEGVDLWWHELMQQAGDECEPEWCDAEDPLFILYTSGSTGKPKGVVHTIGGYMLYVATTFKYVFDFHPEDVFWCTADIGWITGHSYVTYGPLANGATSVLFEGIPTYPDEGRLWSIVDKYKVTKFYTAPTAIRMLMKFGDDPVTKHSRASLQVLGTVGEPINPEAWLWYHRVVGSQRCPIVDTFWQTETGGHMLTPLPGATPMKPGSASFPFFGVAPAILNESGEELEGEAEGYLVFKQPWPGIMRTVYGNHTRFETTYFKKFPGYYVTGDGCRRDQDGYYWITGRIDDMLNVSGHLLSTAEVESALVEHEAVAEAAVVGHPHPVKGECLYCFVTLCDGHTFSPTLTEELKKQIREKIGPIATPDYIQNAPGLPKTRSGKIMRRVLRKIAQNDHDLGDTSTVADPSVINHLFSHRCLTTQ

Gene Information

Entrez Gene ID
60525
Gene Name
acyl-CoA synthetase short-chain family member 2
Gene Symbol
Acss2
Species
Mus musculus

Gene Ontology (GO Annotations)

GO ID Source Type Description
GO:0005737 IDA:MGI C cytoplasm
GO:0005634 IEA:Ensembl C nucleus
GO:0005524 IEA:UniProtKB-KW F ATP binding
GO:0003987 IDA:MGI F acetate-CoA ligase activity
GO:0019413 IEA:Ensembl P acetate biosynthetic process
GO:0006085 IDA:MGI P acetyl-CoA biosynthetic process
GO:0019542 IEA:Ensembl P propionate biosynthetic process

KEGG Pathway Links

KEGG Pathway ID Description
mmu01200 Carbon metabolism
mmu00010 Glycolysis / Gluconeogenesis
mmu00620 Pyruvate metabolism

Domain Information

InterPro Annotations

Accession Description
IPR025110 AMP-binding enzyme C-terminal domain
IPR020845 AMP-binding, conserved site
IPR000873 AMP-dependent synthetase/ligase

UniProt Annotations

Entry Information

Gene Name
acyl-CoA synthetase short-chain family member 2
Protein Entry
ACSA_MOUSE
UniProt ID
Q9QXG4
Species
Mouse

Comments

Comment Type Description
Catalytic Activity ATP + acetate + CoA = AMP + diphosphate + acetyl-CoA.
Function Activates acetate so that it can be used for lipid synthesis or for energy generation.
Similarity Belongs to the ATP-dependent AMP-binding enzyme family. {ECO:0000305}.
Subcellular Location Cytoplasm {ECO:0000250}.

Identical and Related Proteins

Unique RefSeq proteins for LMP005223 (as displayed in Record Overview)

Protein GI Database Accession Length Protein Name
31980996 RefSeq NP_062785 701 acetyl-coenzyme A synthetase, cytoplasmic

Identical Sequences to LMP005223 proteins

Reference Database Accession Length Protein Name
GI:31980996 DBBJ BAC35571.1 701 unnamed protein product [Mus musculus]
GI:31980996 GenBank AAH51432.1 701 Acyl-CoA synthetase short-chain family member 2 [Mus musculus]
GI:31980996 SwissProt Q9QXG4.2 701 RecName: Full=Acetyl-coenzyme A synthetase, cytoplasmic; AltName: Full=Acetate--CoA ligase; AltName: Full=Acetyl-CoA synthetase; Short=ACS; Short=AceCS; AltName: Full=Acyl-CoA synthetase short-chain family member 2; AltName: Full=Acyl-activating enzyme [Mus musculus]

Related Sequences to LMP005223 proteins

Reference Database Accession Length Protein Name
GI:31980996 DBBJ BAC04235.1 701 unnamed protein product [Mus musculus]
GI:31980996 DBBJ BAC26019.1 701 unnamed protein product [Mus musculus]
GI:31980996 DBBJ BAC26243.1 701 unnamed protein product [Mus musculus]
GI:31980996 GenBank EDL06127.1 717 acyl-CoA synthetase short-chain family member 2, partial [Mus musculus]
GI:31980996 RefSeq NP_001101263.1 701 acetyl-coenzyme A synthetase, cytoplasmic [Rattus norvegicus]
GI:31980996 RefSeq XP_006500036.1 758 PREDICTED: acetyl-coenzyme A synthetase, cytoplasmic isoform X1 [Mus musculus]