Gene/Proteome Database (LMPD)
LMPD ID
LMP005309
Gene ID
Species
Homo sapiens (Human)
Gene Name
phosphatidylinositol glycan anchor biosynthesis, class Z
Gene Symbol
Synonyms
GPI-MT-IV; PIG-Z; SMP3
Chromosome
3
Map Location
3q29
Summary
The glycosylphosphatidylinositol (GPI) anchor is a glycolipid found on many blood cells that serves to anchor proteins to the cell surface. This gene encodes a protein that is localized to the endoplasmic reticulum, and is involved in GPI anchor biosynthesis. As shown for the yeast homolog, which is a member of a family of dolichol-phosphate-mannose (Dol-P-Man)-dependent mannosyltransferases, this protein can also add a side-branching fourth mannose to GPI precursors during the assembly of GPI anchors. [provided by RefSeq, Jul 2008]
Orthologs
Proteins
| GPI mannosyltransferase 4 | |
|---|---|
| Refseq ID | NP_079439 |
| Protein GI | 30581137 |
| UniProt ID | Q86VD9 |
| mRNA ID | NM_025163 |
| Length | 579 |
| RefSeq Status | REVIEWED |
| MQICGSSVASVAAGTSFQVLGPVCWQQLDLKMAVRVLWGGLSLLRVLWCLLPQTGYVHPDEFFQSPEVMAEDILGVQAARPWEFYPSSSCRSVLFPLLISGSTFWLLRLWEELGPWPGLVSGYALLVGPRLLLTALSFALDGAVYHLAPPMGADRWNALALLSGSYVTLVFYTRTFSNTIEGLLFTWLLVLVSSHVTWGPTRKEPAPGPRWRSWLLGGIVAAGFFNRPTFLAFAVVPLYLWGTRGATNPGLKSLTREALVLLPGAALTAAVFVATDSWYFSSPATSRNLVLTPVNFLHYNLNPQNLARHGTHARLTHLAVNGFLLFGVLHAQALQAAWQRLQVGLQASAQMGLLRALGARSLLSSPRSYLLLLYFMPLALLSAFSHQEARFLIPLLVPLVLLCSPQTQPVPWKGTVVLFNALGALLFGCLHQGGLVPGLEYLEQVVHAPVLPSTPTHYTLLFTHTYMPPRHLLHLPGLGAPVEVVDMGGTEDWALCQTLKSFTRQPACQVAGGPWLCRLFVVTPGTTRRAVEKCSFPFKNETLLFPHLTLEDPPALSSLLSGAWRDHLSLHIVELGEET | |
Gene Information
Entrez Gene ID
Gene Name
phosphatidylinositol glycan anchor biosynthesis, class Z
Gene Symbol
Species
Homo sapiens
Gene Ontology (GO Annotations)
| GO ID | Source | Type | Description |
|---|---|---|---|
| GO:0016757 | IEA:UniProtKB-KW | F | transferase activity, transferring glycosyl groups |
KEGG Pathway Links
Domain Information
InterPro Annotations
| Accession | Description |
|---|---|
| IPR005599 | GPI mannosyltransferase |
UniProt Annotations
Entry Information
Gene Name
phosphatidylinositol glycan anchor biosynthesis, class Z
Protein Entry
PIGZ_HUMAN
UniProt ID
Species
Human
Identical and Related Proteins
Unique RefSeq proteins for LMP005309 (as displayed in Record Overview)
| Protein GI | Database | Accession | Length | Protein Name |
|---|---|---|---|---|
| 30581137 | RefSeq | NP_079439 | 579 | GPI mannosyltransferase 4 |
Identical Sequences to LMP005309 proteins
| Reference | Database | Accession | Length | Protein Name |
|---|---|---|---|---|
| GI:30581137 | SwissProt | Q86VD9.4 | 579 | RecName: Full=GPI mannosyltransferase 4; AltName: Full=GPI mannosyltransferase IV; Short=GPI-MT-IV; AltName: Full=Phosphatidylinositol-glycan biosynthesis class Z protein; Short=PIG-Z; AltName: Full=SMP3 homolog; Short=hSMP3 [Homo sapiens] |
Related Sequences to LMP005309 proteins
| Reference | Database | Accession | Length | Protein Name |
|---|---|---|---|---|
| GI:30581137 | DBBJ | BAB14263.1 | 579 | unnamed protein product [Homo sapiens] |
| GI:30581137 | EMBL | CAE90685.1 | 579 | unnamed protein product [Homo sapiens] |
| GI:30581137 | GenBank | AAH44640.1 | 579 | Phosphatidylinositol glycan anchor biosynthesis, class Z [Homo sapiens] |
| GI:30581137 | GenBank | EAW53618.1 | 579 | phosphatidylinositol glycan, class Z [Homo sapiens] |
| GI:30581137 | GenBank | ACQ18669.1 | 579 | Sequence 583 from patent US 7510850 |
| GI:30581137 | GenBank | AIC60815.1 | 579 | PIGZ, partial [synthetic construct] |