Gene/Proteome Database (LMPD)

LMPD ID
LMP005850
Gene ID
230801
Species
Mus musculus (Mouse)
Gene Name
phosphatidylinositol glycan anchor biosynthesis, class V
Gene Symbol
Pigv
Synonyms
B330013B03; D430024F16Rik
Alternate Names
GPI mannosyltransferase 2; PIG-V; GPI-MT-II; GPI mannosyltransferase II; phosphatidylinositol glycan class V; phosphatidylinositol glycan, class V; phosphatidylinositol-glycan biosynthesis class V protein
Chromosome
4
Map Location
4 D3|4
EC Number
2.4.1.-

Proteins

GPI mannosyltransferase 2 isoform 1
Refseq ID NP_848813
Protein GI 225543175
UniProt ID Q7TPN3
mRNA ID NM_178698
Length 493
RefSeq Status VALIDATED
MGLLDPSQKEVLRFAVNCRILTLVLQALFNLIIPDHHADAFCPPRLAPSGSADQLVEGLLGGLSRWDAEHFLFIAEHGYLYEHNFAFFPGFPLALLMGTELLRPLQGLLSQRSCLLVSVALLNLLFSVLAAVALHDLGCLVLHCPRQALCAALLFCISPANVFLAAGYSEALFAFLTFSAMGQLERGRGWASGLLFALAAGVRSNGLVSLGFLLHSQCRGFCSSLAVLSPWKPLVKLMASVCLSVLIVSLPFALFQYRAYIQFCSPGSAPSIPEPLLQLAADKGYRLAGENAPPWCSWDLPLIYNYIQDVYWNVGLLRYYELKQVPNFLLATPVTVLVVWATWTYVTTHPWLCLTLGLQRTKDRENPEKPHRGFLSPKVFVYLVHAAALLVFGGLCMHVQVLTRFLASSTPIMYWFPAHLLQDQEPLLRCVDTEPGKLPQEKSPPGQKAPRNCLMKLFYDWKRCSPVTRCVLVYFLTYWLLGLILHCNFLPWT
GPI mannosyltransferase 2 isoform 2
Refseq ID NP_001139427
Protein GI 225543177
UniProt ID Q7TPN3
mRNA ID NM_001145955
Length 211
RefSeq Status VALIDATED
MGLLDPSQKEVLRFAVNCRILTLVLQDVYWNVGLLRYYELKQVPNFLLATPVTVLVVWATWTYVTTHPWLCLTLGLQRTKDRENPEKPHRGFLSPKVFVYLVHAAALLVFGGLCMHVQVLTRFLASSTPIMYWFPAHLLQDQEPLLRCVDTEPGKLPQEKSPPGQKAPRNCLMKLFYDWKRCSPVTRCVLVYFLTYWLLGLILHCNFLPWT
GPI mannosyltransferase 2 isoform 3
Refseq ID NP_001139428
Protein GI 225543179
UniProt ID Q7TPN3
mRNA ID NM_001145956
Length 119
RefSeq Status VALIDATED
MGLLDPSQKEVLRFAVNCRILTLVLQVLTRFLASSTPIMYWFPAHLLQDQEPLLRCVDTEPGKLPQEKSPPGQKAPRNCLMKLFYDWKRCSPVTRCVLVYFLTYWLLGLILHCNFLPWT

Gene Information

Entrez Gene ID
230801
Gene Name
phosphatidylinositol glycan anchor biosynthesis, class V
Gene Symbol
Pigv
Species
Mus musculus

Gene Ontology (GO Annotations)

GO ID Source Type Description
GO:0005789 IEA:Ensembl C endoplasmic reticulum membrane
GO:0016021 IEA:UniProtKB-KW C integral component of membrane
GO:0000030 IEA:Ensembl F mannosyltransferase activity
GO:0006506 IEA:UniProtKB-UniPathway P GPI anchor biosynthetic process

KEGG Pathway Links

KEGG Pathway ID Description
mmu00563 Glycosylphosphatidylinositol(GPI)-anchor biosynthesis
mmu01100 Metabolic pathways

REACTOME Pathway Links

REACTOME Pathway ID Description
5893244 Synthesis of glycosylphosphatidylinositol (GPI)

Domain Information

InterPro Annotations

Accession Description
IPR007315 GPI_Mannosyltransferase_2

UniProt Annotations

Entry Information

Gene Name
phosphatidylinositol glycan anchor biosynthesis, class V
Protein Entry
PIGV_MOUSE
UniProt ID
Q7TPN3
Species
Mouse

Comments

Comment Type Description
Alternative Products Event=Alternative splicing; Named isoforms=2; Name=1; IsoId=Q7TPN3-1; Sequence=Displayed; Name=2; IsoId=Q7TPN3-2; Sequence=VSP_019840; Note=No experimental confirmation available.;
Function Alpha-1,6-mannosyltransferase involved in glycosylphosphatidylinositol-anchor biosynthesis. Transfers the second mannose to the glycosylphosphatidylinositol during GPI precursor assembly (By similarity). {ECO:0000250}.
Pathway Glycolipid biosynthesis; glycosylphosphatidylinositol- anchor biosynthesis.
Ptm Not N-glycosylated. {ECO:0000250}.
Sequence Caution Sequence=BAC33023.1; Type=Erroneous initiation; Evidence={ECO:0000305};
Similarity Belongs to the PIGV family. {ECO:0000305}.
Subcellular Location Endoplasmic reticulum membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}.

Identical and Related Proteins

Unique RefSeq proteins for LMP005850 (as displayed in Record Overview)

Protein GI Database Accession Length Protein Name
225543175 RefSeq NP_848813 493 GPI mannosyltransferase 2 isoform 1
225543177 RefSeq NP_001139427 211 GPI mannosyltransferase 2 isoform 2
225543179 RefSeq NP_001139428 119 GPI mannosyltransferase 2 isoform 3

Identical Sequences to LMP005850 proteins

Reference Database Accession Length Protein Name
GI:225543175 DBBJ BAC32773.1 493 unnamed protein product [Mus musculus]
GI:225543179 DBBJ BAC37950.1 119 unnamed protein product [Mus musculus]
GI:225543175 DBBJ BAC38047.1 493 unnamed protein product [Mus musculus]
GI:225543179 DBBJ BAE28458.1 119 unnamed protein product [Mus musculus]
GI:225543179 GenBank EDL30050.1 119 phosphatidylinositol glycan anchor biosynthesis, class V, isoform CRA_a [Mus musculus]
GI:225543175 GenBank EDL30052.1 493 phosphatidylinositol glycan anchor biosynthesis, class V, isoform CRA_c [Mus musculus]
GI:225543179 GenBank EDL30053.1 119 phosphatidylinositol glycan anchor biosynthesis, class V, isoform CRA_a [Mus musculus]
GI:225543177 GenBank EDL30054.1 211 phosphatidylinositol glycan anchor biosynthesis, class V, isoform CRA_d [Mus musculus]
GI:225543175 RefSeq XP_006538810.1 493 PREDICTED: GPI mannosyltransferase 2 isoform X1 [Mus musculus]
GI:225543175 SwissProt Q7TPN3.2 493 RecName: Full=GPI mannosyltransferase 2; AltName: Full=GPI mannosyltransferase II; Short=GPI-MT-II; AltName: Full=Phosphatidylinositol-glycan biosynthesis class V protein; Short=PIG-V [Mus musculus]

Related Sequences to LMP005850 proteins

Reference Database Accession Length Protein Name
GI:225543177 DBBJ BAC32773.1 493 unnamed protein product [Mus musculus]
GI:225543179 DBBJ BAC32773.1 493 unnamed protein product [Mus musculus]
GI:225543175 DBBJ BAC33023.1 550 unnamed protein product, partial [Mus musculus]
GI:225543175 DBBJ BAC34995.1 493 unnamed protein product [Mus musculus]
GI:225543177 DBBJ BAC38047.1 493 unnamed protein product [Mus musculus]
GI:225543179 DBBJ BAC38047.1 493 unnamed protein product [Mus musculus]
GI:225543175 GenBank AAH55060.1 493 Phosphatidylinositol glycan anchor biosynthesis, class V [Mus musculus]
GI:225543179 GenBank EDL30052.1 493 phosphatidylinositol glycan anchor biosynthesis, class V, isoform CRA_c [Mus musculus]
GI:225543177 GenBank EDL30052.1 493 phosphatidylinositol glycan anchor biosynthesis, class V, isoform CRA_c [Mus musculus]
GI:225543175 RefSeq NP_001010966.1 492 GPI mannosyltransferase 2 [Rattus norvegicus]
GI:225543177 RefSeq NP_848813.3 493 GPI mannosyltransferase 2 isoform 1 [Mus musculus]
GI:225543175 RefSeq XP_006239117.1 492 PREDICTED: GPI mannosyltransferase 2 isoform X1 [Rattus norvegicus]
GI:225543179 RefSeq XP_006538810.1 493 PREDICTED: GPI mannosyltransferase 2 isoform X1 [Mus musculus]
GI:225543177 RefSeq XP_006538810.1 493 PREDICTED: GPI mannosyltransferase 2 isoform X1 [Mus musculus]
GI:225543179 RefSeq XP_008762383.1 118 PREDICTED: GPI mannosyltransferase 2 isoform X4 [Rattus norvegicus]
GI:225543175 SwissProt Q5KR61.1 492 RecName: Full=GPI mannosyltransferase 2; AltName: Full=GPI mannosyltransferase II; Short=GPI-MT-II; AltName: Full=Phosphatidylinositol-glycan biosynthesis class V protein; Short=PIG-V [Rattus norvegicus]
GI:225543179 SwissProt Q7TPN3.2 493 RecName: Full=GPI mannosyltransferase 2; AltName: Full=GPI mannosyltransferase II; Short=GPI-MT-II; AltName: Full=Phosphatidylinositol-glycan biosynthesis class V protein; Short=PIG-V [Mus musculus]
GI:225543177 SwissProt Q7TPN3.2 493 RecName: Full=GPI mannosyltransferase 2; AltName: Full=GPI mannosyltransferase II; Short=GPI-MT-II; AltName: Full=Phosphatidylinositol-glycan biosynthesis class V protein; Short=PIG-V [Mus musculus]