Gene/Proteome Database (LMPD)

LMPD ID
LMP006238
Gene ID
70166
Species
Mus musculus (Mouse)
Gene Name
lipase, family member N
Gene Symbol
Lipn
Synonyms
2210418G03Rik; Lipl4
Alternate Names
lipase member N; lipase-like, ab-hydrolase domain containing 4; lipase-like abhydrolase domain-containing protein 4
Chromosome
19
Map Location
19 C1|19
EC Number
3.1.1.-

Proteins

lipase member N precursor
Refseq ID NP_081616
Protein GI 124249208
UniProt ID Q3U4B4
mRNA ID NM_027340
Length 400
RefSeq Status PROVISIONAL
MPMMWLFLTTACLIPGTLSAGGFLDFENKVNPEVWMNASEIIMYNGYPSEEYDVTTADGYILAINRIPHGRAQTGQTGPRPVVYMQHALFADNAYWLENFANGSLGFILADAGYDVWMGNSRGNTWSRRHKTLSANEEKFWAFSFNEMAKYDLPGIIDFIVNKTGQEKLYFIGHSLGTTIGFVAFSTMPELAQRIKMNFALGPVISFKYPTSVFTNLFLLPKSIIKLVFGTKGVLLEDKNARMSFITFCNQKLLQPLCSEFMSLWAGFNKKNMNMSRLDVYMAHAPTGSSIQNMLHIKQLYRSDEFRAYDWGSEAENMNHYNQSYPPLYDLTAMKVPTAIWAGGHDVLVTPQDVARILPQITNLRYFKQFPDWNHFDFVWGLDAPQRLYSKIISLMKEYF
sig_peptide: 1..19 inference: COORDINATES: ab initio prediction:SignalP:4.0 calculated_mol_wt: 2127 peptide sequence: MPMMWLFLTTACLIPGTLS mat_peptide: 20..400 product: Lipase member N experiment: experimental evidence, no additional details recorded note: propagated from UniProtKB/Swiss-Prot (Q3U4B4.1) calculated_mol_wt: 43635 peptide sequence: AGGFLDFENKVNPEVWMNASEIIMYNGYPSEEYDVTTADGYILAINRIPHGRAQTGQTGPRPVVYMQHALFADNAYWLENFANGSLGFILADAGYDVWMGNSRGNTWSRRHKTLSANEEKFWAFSFNEMAKYDLPGIIDFIVNKTGQEKLYFIGHSLGTTIGFVAFSTMPELAQRIKMNFALGPVISFKYPTSVFTNLFLLPKSIIKLVFGTKGVLLEDKNARMSFITFCNQKLLQPLCSEFMSLWAGFNKKNMNMSRLDVYMAHAPTGSSIQNMLHIKQLYRSDEFRAYDWGSEAENMNHYNQSYPPLYDLTAMKVPTAIWAGGHDVLVTPQDVARILPQITNLRYFKQFPDWNHFDFVWGLDAPQRLYSKIISLMKEYF

Gene Information

Entrez Gene ID
70166
Gene Name
lipase, family member N
Gene Symbol
Lipn
Species
Mus musculus

Gene Ontology (GO Annotations)

GO ID Source Type Description
GO:0005576 IEA:UniProtKB-KW C extracellular region
GO:0016788 IEA:InterPro F hydrolase activity, acting on ester bonds
GO:0016042 IEA:UniProtKB-KW P lipid catabolic process

Domain Information

InterPro Annotations

Accession Description
IPR029058 Alpha/Beta hydrolase fold
IPR000073 Alpha/beta hydrolase fold-1
IPR025483 Lipase, eukaryotic
IPR006693 Partial AB-hydrolase lipase domain

UniProt Annotations

Entry Information

Gene Name
lipase, family member N
Protein Entry
LIPN_MOUSE
UniProt ID
Q3U4B4
Species
Mouse

Comments

Comment Type Description
Function Plays a highly specific role in the last step of keratinocyte differentiation. May have an essential function in lipid metabolism of the most differentiated epidermal layers (By similarity). {ECO:0000250}.
Similarity Belongs to the AB hydrolase superfamily. Lipase family. {ECO:0000305}.
Subcellular Location Secreted {ECO:0000305}.

Identical and Related Proteins

Unique RefSeq proteins for LMP006238 (as displayed in Record Overview)

Protein GI Database Accession Length Protein Name
124249208 RefSeq NP_081616 400 lipase member N precursor

Identical Sequences to LMP006238 proteins

Reference Database Accession Length Protein Name
GI:124249208 DBBJ BAE32519.1 400 unnamed protein product [Mus musculus]
GI:124249208 RefSeq XP_006527396.1 400 PREDICTED: lipase member N isoform X1 [Mus musculus]
GI:124249208 SwissProt Q3U4B4.1 400 RecName: Full=Lipase member N; AltName: Full=Lipase-like abhydrolase domain-containing protein 4; Flags: Precursor [Mus musculus]

Related Sequences to LMP006238 proteins

Reference Database Accession Length Protein Name
GI:124249208 RefSeq NP_001178884.1 398 lipase member N precursor [Rattus norvegicus]
GI:124249208 RefSeq XP_003506006.1 400 PREDICTED: lipase member N [Cricetulus griseus]
GI:124249208 RefSeq XP_005063740.1 400 PREDICTED: lipase member N [Mesocricetus auratus]
GI:124249208 RefSeq XP_005352213.1 400 PREDICTED: lipase member N [Microtus ochrogaster]
GI:124249208 RefSeq XP_006984079.1 400 PREDICTED: lipase member N [Peromyscus maniculatus bairdii]
GI:124249208 RefSeq XP_007633247.1 400 PREDICTED: lipase member N [Cricetulus griseus]