Gene/Proteome Database (LMPD)

LMPD ID
LMP006461
Gene ID
381925
Species
Mus musculus (Mouse)
Gene Name
phosphatidic acid phosphatase type 2 domain containing 1A
Gene Symbol
Ppapdc1a
Synonyms
C030048B12Rik; Gm1090
Alternate Names
phosphatidate phosphatase PPAPDC1A; phosphatidic acid phosphatase type 2 domain-containing protein 1A
Chromosome
7
Map Location
7 F3|7
EC Number
3.1.3.4

Proteins

phosphatidate phosphatase PPAPDC1A
Refseq ID NP_001074432
Protein GI 124377995
UniProt ID Q0VBU9
mRNA ID NM_001080963
Length 271
RefSeq Status PROVISIONAL
MRELAIEIGVRALLFGVFVFTEFLDPFQRVIQPEEIWLYKNPLVQSDNIPTRLMFAISFLTPLAVICVVKIIRRTDKTEIKEAFLAVSLALALNGVCTNTIKLIVGRPRPDFFYRCFPDGVMNSEMRCTGDPDLVSEGRKSFPSIHSSFAFSGLGFTTFYLAGKLHCFTESGRGKSWRLCAAILPLYCAMMIALSRMCDYKHHWQDSFVGGVIGLIFAYICYRQHYPPLANTACHKPYVSLRVPTSLKKEERPTADSAPSLPLEGITEGPV

Gene Information

Entrez Gene ID
381925
Gene Name
phosphatidic acid phosphatase type 2 domain containing 1A
Gene Symbol
Ppapdc1a
Species
Mus musculus

Gene Ontology (GO Annotations)

GO ID Source Type Description
GO:0016021 IEA:UniProtKB-KW C integral component of membrane
GO:0008195 IEA:UniProtKB-EC F phosphatidate phosphatase activity
GO:0046839 IEA:Ensembl P phospholipid dephosphorylation

REACTOME Pathway Links

REACTOME Pathway ID Description
5893294 Fcgamma receptor (FCGR) dependent phagocytosis
5892920 Immune System
5892919 Innate Immune System
5893293 Role of phospholipids in phagocytosis

Domain Information

InterPro Annotations

Accession Description
IPR028668 Phosphatidate phosphatase PPAPDC1A/PPAPDC1B
IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase

UniProt Annotations

Entry Information

Gene Name
phosphatidic acid phosphatase type 2 domain containing 1A
Protein Entry
PPC1A_MOUSE
UniProt ID
Q0VBU9
Species
Mouse

Comments

Comment Type Description
Catalytic Activity A 1,2-diacylglycerol 3-phosphate + H(2)O = a 1,2-diacyl-sn-glycerol + phosphate.
Enzyme Regulation Inhibited by N-ethylmaleimide. {ECO:0000250}.
Function Displays magnesium-independent phosphatidate phosphatase activity in vitro. Catalyzes the conversion of phosphatidic acid to diacylglycerol (By similarity). {ECO:0000250}.
Similarity Belongs to the PA-phosphatase related phosphoesterase family. {ECO:0000305}.
Subcellular Location Membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000305}.

Identical and Related Proteins

Unique RefSeq proteins for LMP006461 (as displayed in Record Overview)

Protein GI Database Accession Length Protein Name
124377995 RefSeq NP_001074432 271 phosphatidate phosphatase PPAPDC1A

Identical Sequences to LMP006461 proteins

Reference Database Accession Length Protein Name
GI:124377995 GenBank AAI20498.1 271 Phosphatidic acid phosphatase type 2 domain containing 1A [Mus musculus]
GI:124377995 SwissProt Q0VBU9.1 271 RecName: Full=Phosphatidate phosphatase PPAPDC1A; AltName: Full=Phosphatidic acid phosphatase type 2 domain-containing protein 1A [Mus musculus]

Related Sequences to LMP006461 proteins

Reference Database Accession Length Protein Name
GI:124377995 RefSeq NP_001178560.1 271 phosphatidate phosphatase PPAPDC1A [Rattus norvegicus]
GI:124377995 RefSeq XP_005320785.1 271 PREDICTED: phosphatidate phosphatase PPAPDC1A isoform X1 [Ictidomys tridecemlineatus]
GI:124377995 RefSeq XP_006144021.1 271 PREDICTED: phosphatidate phosphatase PPAPDC1A [Tupaia chinensis]
GI:124377995 RefSeq XP_006977053.1 271 PREDICTED: phosphatidate phosphatase PPAPDC1A [Peromyscus maniculatus bairdii]
GI:124377995 RefSeq XP_007623048.1 363 PREDICTED: phosphatidate phosphatase PPAPDC1A isoform X3 [Cricetulus griseus]
GI:124377995 RefSeq XP_008825515.1 271 PREDICTED: phosphatidate phosphatase PPAPDC1A [Nannospalax galili]