Gene/Proteome Database (LMPD)

LMPD ID
LMP006481
Gene ID
57319
Species
Mus musculus (Mouse)
Gene Name
sphingomyelin phosphodiesterase, acid-like 3A
Gene Symbol
Smpdl3a
Synonyms
0610010C24Rik; AI529588; ASM3A; ASML3; ASML3A
Alternate Names
acid sphingomyelinase-like phosphodiesterase 3a; ASM-like phosphodiesterase 3a
Chromosome
10
Map Location
10 B4|10
EC Number
3.1.4.-

Proteins

acid sphingomyelinase-like phosphodiesterase 3a precursor
Refseq ID NP_065586
Protein GI 114431242
UniProt ID P70158
mRNA ID NM_020561
Length 445
RefSeq Status VALIDATED
MALLGNFLCCLLVAWLCGPGLGVPLAPADRAPAVGQFWHVTDLHLDPTYHITDDRTKVCASSKGANASNPGPFGDVLCDSPYQLILSAFDFIKNSGQEASFMIWTGDSPPHVPVPELSTGTVIKVITNMTMTVQNLFPNLQVFPALGNHDYWPQDQLPIVTSKVYSAVADLWKPWLGEEAISTLKKGGFYSQKVASNPGLRIISLNTNLYYGPNIMTLNKTDPANQFEWLENTLNSSLWNKEKVYIIAHVPVGYLPYATDTPAIRQYYNEKLLDIFRRYSSVIAGQFYGHTHRDSLMVLSDKNGNPLNSVFVAPAVTPVKGVLQKETNNPGVRLFQYKPGDYTLLDMVQYYLNLTEANLKGESNWTLEYVLTQAYSVADLQPKSLYALVQQFATKDSKQFLKYYHYYFVSYDSSATCDQHCKTLQVCAIMNLDSMSYDDCLKQHL
sig_peptide: 1..22 inference: COORDINATES: ab initio prediction:SignalP:4.0 calculated_mol_wt: 2265 peptide sequence: MALLGNFLCCLLVAWLCGPGLG mat_peptide: 23..445 product: Acid sphingomyelinase-like phosphodiesterase 3a experiment: experimental evidence, no additional details recorded note: propagated from UniProtKB/Swiss-Prot (P70158.2) calculated_mol_wt: 47611 peptide sequence: VPLAPADRAPAVGQFWHVTDLHLDPTYHITDDRTKVCASSKGANASNPGPFGDVLCDSPYQLILSAFDFIKNSGQEASFMIWTGDSPPHVPVPELSTGTVIKVITNMTMTVQNLFPNLQVFPALGNHDYWPQDQLPIVTSKVYSAVADLWKPWLGEEAISTLKKGGFYSQKVASNPGLRIISLNTNLYYGPNIMTLNKTDPANQFEWLENTLNSSLWNKEKVYIIAHVPVGYLPYATDTPAIRQYYNEKLLDIFRRYSSVIAGQFYGHTHRDSLMVLSDKNGNPLNSVFVAPAVTPVKGVLQKETNNPGVRLFQYKPGDYTLLDMVQYYLNLTEANLKGESNWTLEYVLTQAYSVADLQPKSLYALVQQFATKDSKQFLKYYHYYFVSYDSSATCDQHCKTLQVCAIMNLDSMSYDDCLKQHL

Gene Information

Entrez Gene ID
57319
Gene Name
sphingomyelin phosphodiesterase, acid-like 3A
Gene Symbol
Smpdl3a
Species
Mus musculus

Gene Ontology (GO Annotations)

GO ID Source Type Description
GO:0005615 IEA:InterPro C extracellular space
GO:0016798 IEA:UniProtKB-KW F hydrolase activity, acting on glycosyl bonds
GO:0004767 IEA:InterPro F sphingomyelin phosphodiesterase activity
GO:0006685 IEA:InterPro P sphingomyelin catabolic process

Domain Information

InterPro Annotations

Accession Description
IPR017064 Acid sphingomyelinase-like phosphodiesterase, predicted
IPR004843 Calcineurin-like phosphoesterase domain, apaH type
IPR029052 Metallo-dependent phosphatase-like

UniProt Annotations

Entry Information

Gene Name
sphingomyelin phosphodiesterase, acid-like 3A
Protein Entry
ASM3A_MOUSE
UniProt ID
P70158
Species
Mouse

Comments

Comment Type Description
Similarity Belongs to the acid sphingomyelinase family. {ECO:0000305}.
Subcellular Location Secreted {ECO:0000250}.

Identical and Related Proteins

Unique RefSeq proteins for LMP006481 (as displayed in Record Overview)

Protein GI Database Accession Length Protein Name
114431242 RefSeq NP_065586 445 acid sphingomyelinase-like phosphodiesterase 3a precursor

Identical Sequences to LMP006481 proteins

Reference Database Accession Length Protein Name
GI:114431242 DBBJ BAE30607.1 445 unnamed protein product [Mus musculus]
GI:114431242 DBBJ BAE31096.1 445 unnamed protein product [Mus musculus]
GI:114431242 GenBank EDL05124.1 445 sphingomyelin phosphodiesterase, acid-like 3A, isoform CRA_a [Mus musculus]
GI:114431242 GenBank AAI39289.1 445 Sphingomyelin phosphodiesterase, acid-like 3A [Mus musculus]
GI:114431242 GenBank AAI39290.1 445 Sphingomyelin phosphodiesterase, acid-like 3A [Mus musculus]
GI:114431242 SwissProt P70158.2 445 RecName: Full=Acid sphingomyelinase-like phosphodiesterase 3a; Short=ASM-like phosphodiesterase 3a; Flags: Precursor [Mus musculus]

Related Sequences to LMP006481 proteins

Reference Database Accession Length Protein Name
GI:114431242 EMBL CAA69329.1 445 acid sphingomyelinase-like phosphodiesterase [Mus musculus]
GI:114431242 GenBank AAH82029.1 445 Sphingomyelin phosphodiesterase, acid-like 3A [Rattus norvegicus]
GI:114431242 GenBank EDL92885.1 445 sphingomyelin phosphodiesterase, acid-like 3A, isoform CRA_a [Rattus norvegicus]
GI:114431242 RefSeq NP_001005539.1 445 acid sphingomyelinase-like phosphodiesterase 3a precursor [Rattus norvegicus]
GI:114431242 RefSeq XP_005363700.1 450 PREDICTED: acid sphingomyelinase-like phosphodiesterase 3a [Microtus ochrogaster]
GI:114431242 SwissProt Q641Z7.1 445 RecName: Full=Acid sphingomyelinase-like phosphodiesterase 3a; Short=ASM-like phosphodiesterase 3a; Flags: Precursor [Rattus norvegicus]