Gene/Proteome Database (LMPD)

LMPD ID
LMP006487
Gene ID
320581
Species
Mus musculus (Mouse)
Gene Name
isopentenyl-diphosphate delta isomerase 2
Gene Symbol
Idi2
Synonyms
4833405L16Rik; IPPI2
Alternate Names
isopentenyl-diphosphate delta-isomerase 2; IPP isomerase 2; isopentenyl pyrophosphate isomerase 2; isopentenyl-diphosphate Delta-isomerase 2; isopentenyl diphosphate delta-isomerase type 2
Chromosome
13
Map Location
13 A1|13
EC Number
5.3.3.2

Proteins

isopentenyl-diphosphate delta-isomerase 2
Refseq ID NP_796171
Protein GI 28893215
UniProt ID Q8BFZ6
mRNA ID NM_177197
Length 227
RefSeq Status PROVISIONAL
MFQASKTHLDELQLKRLEEMCIVIDKQDQIIGADTKKNCHLMENINKGLLHRAFSVVLFNMKNELLVQQRADAKYTFPGHFTDSCSSHPLYVPEELEEKDALGVRRAALRRLQAELGISQDQISIKDIIFMTRKYHKCQSDAIWGEHEIGYLLLVRKDLMLNPDTREVRRCCYMSQKDVQELLDREARGEEKITPWFRSMVEDFLFSWWPHLEDVSSFVEPDKIYGL

Gene Information

Entrez Gene ID
320581
Gene Name
isopentenyl-diphosphate delta isomerase 2
Gene Symbol
Idi2
Species
Mus musculus

Gene Ontology (GO Annotations)

GO ID Source Type Description
GO:0005777 IEA:UniProtKB-KW C peroxisome
GO:0016787 IEA:InterPro F hydrolase activity
GO:0004452 IEA:UniProtKB-EC F isopentenyl-diphosphate delta-isomerase activity
GO:0046872 IEA:UniProtKB-KW F metal ion binding
GO:0006695 IEA:UniProtKB-KW P cholesterol biosynthetic process
GO:0050992 IEA:UniProtKB-UniPathway P dimethylallyl diphosphate biosynthetic process
GO:0008299 IEA:UniProtKB-KW P isoprenoid biosynthetic process
GO:0045541 IDA:UniProtKB P negative regulation of cholesterol biosynthetic process

KEGG Pathway Links

KEGG Pathway ID Description
mmu01100 Metabolic pathways
mmu00900 Terpenoid backbone biosynthesis

REACTOME Pathway Links

REACTOME Pathway ID Description
5893434 Cholesterol biosynthesis

Domain Information

InterPro Annotations

Accession Description
IPR011876 Isopentenyl-diphosphate delta-isomerase, type 1
IPR000086 NUDIX hydrolase domain
IPR015797 NUDIX hydrolase domain-like

UniProt Annotations

Entry Information

Gene Name
isopentenyl-diphosphate delta isomerase 2
Protein Entry
IDI2_MOUSE
UniProt ID
Q8BFZ6
Species
Mouse

Comments

Comment Type Description
Catalytic Activity Isopentenyl diphosphate = dimethylallyl diphosphate.
Cofactor Name=Mg(2+); Xref=ChEBI:CHEBI:18420; Evidence={ECO:0000250}; Note=Binds 1 Mg(2+) ion per subunit. {ECO:0000250};
Function Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP). {ECO:0000250}.
Pathway Isoprenoid biosynthesis; dimethylallyl diphosphate biosynthesis; dimethylallyl diphosphate from isopentenyl diphosphate: step 1/1.
Similarity Belongs to the IPP isomerase type 1 family. {ECO:0000305}.
Similarity Contains 1 nudix hydrolase domain. {ECO:0000255|PROSITE-ProRule:PRU00794}.
Subcellular Location Peroxisome {ECO:0000250}.

Identical and Related Proteins

Unique RefSeq proteins for LMP006487 (as displayed in Record Overview)

Protein GI Database Accession Length Protein Name
28893215 RefSeq NP_796171 227 isopentenyl-diphosphate delta-isomerase 2

Identical Sequences to LMP006487 proteins

Reference Database Accession Length Protein Name
GI:28893215 DBBJ BAC26418.1 227 unnamed protein product [Mus musculus]
GI:28893215 DBBJ BAC38194.1 227 unnamed protein product [Mus musculus]
GI:28893215 GenBank AAP21674.1 227 isopentenyl diphosphate delta-isomerase type 2 [Mus musculus]
GI:28893215 GenBank AAI25311.1 227 Isopentenyl-diphosphate delta isomerase 2 [Mus musculus]
GI:28893215 GenBank AAI38101.1 227 Isopentenyl-diphosphate delta isomerase 2 [Mus musculus]
GI:28893215 SwissProt Q8BFZ6.1 227 RecName: Full=Isopentenyl-diphosphate delta-isomerase 2; AltName: Full=Isopentenyl pyrophosphate isomerase 2; Short=IPP isomerase 2; Short=IPPI2 [Mus musculus]

Related Sequences to LMP006487 proteins

Reference Database Accession Length Protein Name
GI:28893215 GenBank AAH99586.1 227 Idi2 protein [Mus musculus]
GI:28893215 RefSeq NP_001178937.1 227 isopentenyl-diphosphate delta isomerase 2 [Rattus norvegicus]
GI:28893215 RefSeq XP_006516547.1 237 PREDICTED: isopentenyl-diphosphate delta-isomerase 2 isoform X2 [Mus musculus]
GI:28893215 RefSeq XP_006980243.1 227 PREDICTED: isopentenyl-diphosphate delta-isomerase 2-like [Peromyscus maniculatus bairdii]
GI:28893215 RefSeq XP_008772230.1 231 PREDICTED: isopentenyl-diphosphate delta-isomerase 2-like [Rattus norvegicus]
GI:28893215 RefSeq XP_008770063.1 231 PREDICTED: isopentenyl-diphosphate delta-isomerase 2-like [Rattus norvegicus]