Gene/Proteome Database (LMPD)

LMPD ID
LMP006536
Gene ID
76438
Species
Mus musculus (Mouse)
Gene Name
raftlin lipid raft linker 1
Gene Symbol
Rftn1
Synonyms
2310015N21Rik; AI853526
Alternate Names
raftlin; raft-linking protein
Chromosome
17
Map Location
17 C|17

Proteins

raftlin
Refseq ID NP_852062
Protein GI 33859813
UniProt ID Q6A0D4
mRNA ID NM_181397
Length 554
RefSeq Status PROVISIONAL
MGCSLNKLEKREEKRPGNIYSTLKRPQVETKVDVTYEYCFLEFTTLTAAELPRSSATRLASLRDLPDQLLELYQQGFSLAALHPFVQPTRRQEKILLEHIFRAILVKKTNRSQKAELHDEGYTLELDYCSSLEHLADQKLIPEFIKKVQEAASQGLKFVSVVPQYQPSVSSAGSRRLKPVANSVEDARDVKCTLGDRSSLENDTPKAAETDAATAGVNRRPETKPGSTGDVPSAQQPGIPSPSAENEAGEFPLRGLQPALDRSEGDPSNGPEELPSRKMEIFAFFNRPKSQQKCRQYYPVTIPLQVSKNGQTVSSLDASWLEHMSDHFRKGGVLVNAVFQLGMANDSFYGLTDGVFIFEAVSTEDNRTTQGYDAIVVEQWTVLEGTEVQTDYMPLLNSLAAYGWQLTCVLPTPILKTTREGNVSTKQIVFLQRPCLPQKTKKRESKFQWRFSRNEIHGRQTRKSKGKLSASNKQQAEENEKNLEDQFSKAGDVGNCVLGAPQWGRASEVREQRQGSAAVQNGPAGHNRDSVALRHSNPRAEAELAAGPTPTEAN

Gene Information

Entrez Gene ID
76438
Gene Name
raftlin lipid raft linker 1
Gene Symbol
Rftn1
Species
Mus musculus

Gene Ontology (GO Annotations)

GO ID Source Type Description
GO:0005737 ISO:MGI C cytoplasm
GO:0005768 ISO:MGI C endosome
GO:0070062 IEA:Ensembl C extracellular vesicular exosome
GO:0045121 IEA:Ensembl C membrane raft
GO:0005886 ISO:MGI C plasma membrane
GO:0043234 ISO:MGI C protein complex
GO:0003725 ISO:MGI F double-stranded RNA binding
GO:0050853 IEA:Ensembl P B cell receptor signaling pathway
GO:0002457 IMP:UniProt P T cell antigen processing and presentation
GO:0050852 IMP:UniProt P T cell receptor signaling pathway
GO:0033227 ISO:MGI P dsRNA transport
GO:0040007 IEA:Ensembl P growth
GO:0032620 IMP:UniProt P interleukin-17 production
GO:0001765 IEA:Ensembl P membrane raft assembly
GO:1903044 IMP:UniProt P protein localization to membrane raft
GO:0032596 IMP:UniProt P protein transport into membrane raft
GO:0043330 ISO:MGI P response to exogenous dsRNA
GO:0034138 ISO:MGI P toll-like receptor 3 signaling pathway

Domain Information

InterPro Annotations

Accession Description
IPR028169 Raftlin family

UniProt Annotations

Entry Information

Gene Name
raftlin lipid raft linker 1
Protein Entry
RFTN1_MOUSE
UniProt ID
Q6A0D4
Species
Mouse

Comments

Comment Type Description
Function May play a pivotal role in the formation and/or maintenance of lipid rafts. May regulate B-cell antigen receptor- mediated signaling.
Sequence Caution Sequence=BAD32162.1; Type=Erroneous initiation; Evidence={ECO:0000305}; Sequence=BAE31871.1; Type=Erroneous initiation; Evidence={ECO:0000305};
Similarity Belongs to the raftlin family. {ECO:0000305}.
Subcellular Location Cell membrane {ECO:0000250}; Lipid-anchor {ECO:0000250}. Note=Associates with lipid rafts. {ECO:0000250}.
Tissue Specificity Specifically expressed by lymphocytes. {ECO:0000269|PubMed:12805216}.

Identical and Related Proteins

Unique RefSeq proteins for LMP006536 (as displayed in Record Overview)

Protein GI Database Accession Length Protein Name
33859813 RefSeq NP_852062 554 raftlin

Identical Sequences to LMP006536 proteins

Reference Database Accession Length Protein Name
GI:33859813 DBBJ BAE33473.1 554 unnamed protein product [Mus musculus]
GI:33859813 GenBank AAH52074.1 554 Raftlin lipid raft linker 1 [Mus musculus]
GI:33859813 SwissProt Q6A0D4.4 554 RecName: Full=Raftlin; AltName: Full=Raft-linking protein [Mus musculus]

Related Sequences to LMP006536 proteins

Reference Database Accession Length Protein Name
GI:33859813 DBBJ BAC38515.1 521 unnamed protein product, partial [Mus musculus]
GI:33859813 DBBJ BAD32162.1 626 mKIAA0084 protein, partial [Mus musculus]
GI:33859813 DBBJ BAE31871.1 624 unnamed protein product, partial [Mus musculus]
GI:33859813 DBBJ BAE30971.1 554 unnamed protein product [Mus musculus]
GI:33859813 GenBank EDL23642.1 554 RIKEN cDNA 2310015N21 [Mus musculus]
GI:33859813 GenBank EDM18962.1 554 similar to RIKEN cDNA 2310015N21 (predicted) [Rattus norvegicus]