Gene/Proteome Database (LMPD)

LMPD ID
LMP006611
Gene ID
78753
Species
Mus musculus (Mouse)
Gene Name
lipase, family member M
Gene Symbol
Lipm
Synonyms
4632427C23Rik; AW227514; Lipl3
Alternate Names
lipase member M; lipase-like, ab-hydrolase domain containing 3; lipase-like abhydrolase domain-containing protein 3
Chromosome
19
Map Location
19 C1|19
EC Number
3.1.1.-

Proteins

lipase member M precursor
Refseq ID NP_076392
Protein GI 158533984
UniProt ID Q8K2A6
mRNA ID NM_023903
Length 422
RefSeq Status VALIDATED
MSEILSRVWTVSHRVEIWLLILVAYLLQRNVNSGHLPTKAADPEAFMNVSEIIKHKGYPSEEYEVATEDGYILSVNRIPRGQTRLKKEGSRPVVLLQHGLLGDASNWISNLPNNSLGFILADAGFDVWMGNSRGNTWSRKHKTLSIDQDEFWAFSYDEMARFDLPAVINFILQKTGQKKVYYVGYSQGTTMGFIAFSTMPELAHKIKMYFALAPIATVKYARSPGTKFLLLPDMMIKVLFGRQEFLYQTRFFRQLFIYLCGQMILDQICSNIILLLGGFNTNNMNMSRANVYVAHTPAGTSVQNILHWSQAVNSGELRAFDWGSETKNQEKCNQPTPIRYKVRDMMVPTAMWTGGQDWLSNPDDVKTLLSEVTNLIYHKNIPEWAHVDFIWGLDAPQRVYNEIIHLMKQEPNLPQGTCRVKL
sig_peptide: 1..33 inference: non-experimental evidence, no additional details recorded note: Potential; propagated from UniProtKB/Swiss-Prot (Q8K2A6.1) calculated_mol_wt: 3940 peptide sequence: MSEILSRVWTVSHRVEIWLLILVAYLLQRNVNS mat_peptide: 34..422 product: Lipase member M experiment: experimental evidence, no additional details recorded note: propagated from UniProtKB/Swiss-Prot (Q8K2A6.1) calculated_mol_wt: 44332 peptide sequence: GHLPTKAADPEAFMNVSEIIKHKGYPSEEYEVATEDGYILSVNRIPRGQTRLKKEGSRPVVLLQHGLLGDASNWISNLPNNSLGFILADAGFDVWMGNSRGNTWSRKHKTLSIDQDEFWAFSYDEMARFDLPAVINFILQKTGQKKVYYVGYSQGTTMGFIAFSTMPELAHKIKMYFALAPIATVKYARSPGTKFLLLPDMMIKVLFGRQEFLYQTRFFRQLFIYLCGQMILDQICSNIILLLGGFNTNNMNMSRANVYVAHTPAGTSVQNILHWSQAVNSGELRAFDWGSETKNQEKCNQPTPIRYKVRDMMVPTAMWTGGQDWLSNPDDVKTLLSEVTNLIYHKNIPEWAHVDFIWGLDAPQRVYNEIIHLMKQEPNLPQGTCRVKL

Gene Information

Entrez Gene ID
78753
Gene Name
lipase, family member M
Gene Symbol
Lipm
Species
Mus musculus

Gene Ontology (GO Annotations)

GO ID Source Type Description
GO:0005576 IEA:UniProtKB-KW C extracellular region
GO:0016788 IEA:InterPro F hydrolase activity, acting on ester bonds
GO:0016042 IEA:UniProtKB-KW P lipid catabolic process

Domain Information

InterPro Annotations

Accession Description
IPR029058 Alpha/Beta hydrolase fold
IPR000073 Alpha/beta hydrolase fold-1
IPR025483 Lipase, eukaryotic
IPR006693 Partial AB-hydrolase lipase domain

UniProt Annotations

Entry Information

Gene Name
lipase, family member M
Protein Entry
LIPM_MOUSE
UniProt ID
Q8K2A6
Species
Mouse

Comments

Comment Type Description
Function Plays a highly specific role in the last step of keratinocyte differentiation. May have an essential function in lipid metabolism of the most differentiated epidermal layers (By similarity). {ECO:0000250}.
Similarity Belongs to the AB hydrolase superfamily. Lipase family. {ECO:0000305}.
Subcellular Location Secreted {ECO:0000305}.

Identical and Related Proteins

Unique RefSeq proteins for LMP006611 (as displayed in Record Overview)

Protein GI Database Accession Length Protein Name
158533984 RefSeq NP_076392 422 lipase member M precursor

Identical Sequences to LMP006611 proteins

Reference Database Accession Length Protein Name
GI:158533984 DBBJ BAC29699.1 422 unnamed protein product [Mus musculus]
GI:158533984 DBBJ BAC39517.1 422 unnamed protein product [Mus musculus]
GI:158533984 GenBank AAH31933.1 422 Lipm protein [Mus musculus]
GI:158533984 GenBank EDL41742.1 422 mCG125005 [Mus musculus]
GI:158533984 RefSeq XP_006527529.1 422 PREDICTED: lipase member M isoform X1 [Mus musculus]
GI:158533984 SwissProt Q8K2A6.1 422 RecName: Full=Lipase member M; AltName: Full=Lipase-like abhydrolase domain-containing protein 3; Flags: Precursor [Mus musculus]

Related Sequences to LMP006611 proteins

Reference Database Accession Length Protein Name
GI:158533984 DBBJ BAC29757.1 422 unnamed protein product [Mus musculus]
GI:158533984 GenBank ERE79099.1 422 lipase member M [Cricetulus griseus]
GI:158533984 RefSeq XP_220066.4 422 PREDICTED: lipase member M [Rattus norvegicus]
GI:158533984 RefSeq XP_001079892.1 422 PREDICTED: lipase member M [Rattus norvegicus]
GI:158533984 RefSeq XP_003506007.1 422 PREDICTED: lipase member M [Cricetulus griseus]
GI:158533984 RefSeq XP_007633254.1 422 PREDICTED: lipase member M [Cricetulus griseus]