Gene/Proteome Database (LMPD)
LMPD ID
LMP006693
Gene ID
Species
Homo sapiens (Human)
Gene Name
sulfotransferase family, cytosolic, 2A, dehydroepiandrosterone (DHEA)-preferring, member 1
Gene Symbol
Synonyms
DHEA-ST; DHEAS; HST; ST2; ST2A1; ST2A3; STD; hSTa
Chromosome
19
Map Location
19q13.3
EC Number
2.8.2.-
Summary
This gene encodes a member of the sulfotransferase family. Sulfotransferases aid in the metabolism of drugs and endogenous compounds by converting these substances into more hydrophilic water-soluble sulfate conjugates that can be easily excreted. This protein catalyzes the sulfation of steroids and bile acids in the liver and adrenal glands, and may have a role in the inherited adrenal androgen excess in women with polycystic ovary syndrome. [provided by RefSeq, Mar 2010]
Orthologs
Proteins
| bile salt sulfotransferase | |
|---|---|
| Refseq ID | NP_003158 |
| Protein GI | 29540545 |
| UniProt ID | Q06520 |
| mRNA ID | NM_003167 |
| Length | 285 |
| RefSeq Status | REVIEWED |
| MSDDFLWFEGIAFPTMGFRSETLRKVRDEFVIRDEDVIILTYPKSGTNWLAEILCLMHSKGDAKWIQSVPIWERSPWVESEIGYTALSETESPRLFSSHLPIQLFPKSFFSSKAKVIYLMRNPRDVLVSGYFFWKNMKFIKKPKSWEEYFEWFCQGTVLYGSWFDHIHGWMPMREEKNFLLLSYEELKQDTGRTIEKICQFLGKTLEPEELNLILKNSSFQSMKENKMSNYSLLSVDYVVDKAQLLRKGVSGDWKNHFTVAQAEDFDKLFQEKMADLPRELFPWE | |
Gene Information
Entrez Gene ID
Gene Name
sulfotransferase family, cytosolic, 2A, dehydroepiandrosterone (DHEA)-preferring, member 1
Gene Symbol
Species
Homo sapiens
Gene Ontology (GO Annotations)
| GO ID | Source | Type | Description |
|---|---|---|---|
| GO:0008146 | IEA:InterPro | F | sulfotransferase activity |
KEGG Pathway Links
Domain Information
UniProt Annotations
Entry Information
Gene Name
sulfotransferase family, cytosolic, 2A, dehydroepiandrosterone (DHEA)-preferring, member 1
Protein Entry
ST2A1_HUMAN
UniProt ID
Species
Human
Identical and Related Proteins
Unique RefSeq proteins for LMP006693 (as displayed in Record Overview)
| Protein GI | Database | Accession | Length | Protein Name |
|---|---|---|---|---|
| 29540545 | RefSeq | NP_003158 | 285 | bile salt sulfotransferase |
Identical Sequences to LMP006693 proteins
| Reference | Database | Accession | Length | Protein Name |
|---|---|---|---|---|
| GI:29540545 | DBBJ | BAG36209.1 | 285 | unnamed protein product [Homo sapiens] |
| GI:29540545 | GenBank | AHD69673.1 | 285 | Sequence 687 from patent US 8586006 |
| GI:29540545 | PDB | 3F3Y | 285 | Chain A, Crystal Structure Of Human Cytosolic Sulfotransferase Sult2a1 In Complex With Pap And Lithocholic Acid |
| GI:29540545 | PDB | 3F3Y | 285 | Chain B, Crystal Structure Of Human Cytosolic Sulfotransferase Sult2a1 In Complex With Pap And Lithocholic Acid |
| GI:29540545 | PDB | 3F3Y | 285 | Chain C, Crystal Structure Of Human Cytosolic Sulfotransferase Sult2a1 In Complex With Pap And Lithocholic Acid |
| GI:29540545 | PDB | 3F3Y | 285 | Chain D, Crystal Structure Of Human Cytosolic Sulfotransferase Sult2a1 In Complex With Pap And Lithocholic Acid |
Related Sequences to LMP006693 proteins
| Reference | Database | Accession | Length | Protein Name |
|---|---|---|---|---|
| GI:29540545 | EMBL | CAA49755.1 | 285 | dehydroepiandrosterone sulphotransferase [Homo sapiens] |
| GI:29540545 | GenBank | AAA35758.1 | 285 | dehydroepiandrosterone sulfotransferase [Homo sapiens] |
| GI:29540545 | GenBank | AAB23169.2 | 285 | alcohol/hydroxysteroid sulfotransferase [Homo sapiens] |
| GI:29540545 | GenBank | AAX36841.1 | 286 | sulfotransferase family cytosolic 2A dehydroepiandrosterone-preferring member 1, partial [synthetic construct] |
| GI:29540545 | GenBank | AAX43191.1 | 286 | sulfotransferase family cytosolic 2A dehydroepiandrosterone-preferring member 1, partial [synthetic construct] |
| GI:29540545 | GenBank | ABJ18631.1 | 285 | Sequence 3 from patent US 7056731 |