Gene/Proteome Database (LMPD)

LMPD ID
LMP006703
Gene ID
149998
Species
Homo sapiens (Human)
Gene Name
lipase, member I
Gene Symbol
LIPI
Synonyms
CT17; LPDL; PLA1C
Chromosome
21
Map Location
21q11.2
Summary
The protein encoded by this gene is a phospholipase that hydrolyzes phosphatidic acid to produce lysophosphatidic acid. The encoded protein, which can be inhibited by sodium vanadate, may be found exclusively in sperm. Defects in this gene are a cause of susceptibility to familial hypertrigliceridemia. [provided by RefSeq, Jun 2010]
Orthologs
View orthologs and multiple alignments for LIPI

Proteins

lipase member I
Refseq ID NP_945347
Protein GI 39752679
UniProt ID Q5D1Q2
mRNA ID NM_198996
Length 481
RefSeq Status REVIEWED
MLLKCLHNNLCQKYSAHAFQFSPRNVLWLLVVCLRSDNKRPCLEFSQLSVKDSFRDLFIPRIETILMMYTRNNLNCAEPLFEQNNSLNVNFNTQKKTVWLIHGYRPVGSIPLWLQNFVRILLNEEDMNVIVVDWSRGATTFIYNRAVKNTRKVAVSLSVHIKNLLKHGASLDNFHFIGVSLGAHISGFVGKIFHGQLGRITGLDPAGPRFSRKPPYSRLDYTDAKFVDVIHSDSNGLGIQEPLGHIDFYPNGGNKQPGCPKSIFSGIQFIKCNHQRAVHLFMASLETNCNFISFPCRSYKDYKTSLCVDCDCFKEKSCPRLGYQAKLFKGVLKERMEGRPLRTTVFLDTSGTYPFCTYYFVLSIIVPDKTMMDGSFSFKLLNQLGMIEEPRLYEKNKPFYKLQEVKILAQFYNDFVNISSIGLTYFQSSNLQCSTCTYKIQRLMLKSLTYPERPPLCRYNIVLKDREEVFLNPNTCTPKNT

Gene Information

Entrez Gene ID
149998
Gene Name
lipase, member I
Gene Symbol
LIPI
Species
Homo sapiens

Gene Ontology (GO Annotations)

GO ID Source Type Description
GO:0005576 IEA:UniProtKB-KW C extracellular region
GO:0016787 IEA:UniProtKB-KW F hydrolase activity
GO:0006629 IEA:InterPro P lipid metabolic process

Domain Information

InterPro Annotations

Accession Description
IPR029058 Alpha/Beta hydrolase fold
IPR013818 Lipase, N-terminal
IPR000734 Triacylglycerol lipase family

UniProt Annotations

Entry Information

Gene Name
lipase, member I
Protein Entry
LIPI_HUMAN
UniProt ID
Q5D1Q2
Species
Human

Identical and Related Proteins

Unique RefSeq proteins for LMP006703 (as displayed in Record Overview)

Protein GI Database Accession Length Protein Name
39752679 RefSeq NP_945347 481 lipase member I

Identical Sequences to LMP006703 proteins

Reference Database Accession Length Protein Name

Related Sequences to LMP006703 proteins

Reference Database Accession Length Protein Name
GI:39752679 DBBJ BAG73351.1 481 lipase, member I, partial [synthetic construct]
GI:39752679 GenBank AAP37476.1 481 membrane-associated phospholipase A1 beta [Homo sapiens]
GI:39752679 GenBank AAI40337.1 481 Lipase, member I, partial [synthetic construct]
GI:39752679 GenBank AAI48692.1 481 Lipase, member I [synthetic construct]
GI:39752679 GenBank AHD80119.1 481 Sequence 31584 from patent US 8586006
GI:39752679 RefSeq XP_003819231.1 481 PREDICTED: lipase member I isoform X1 [Pan paniscus]