Gene/Proteome Database (LMPD)

LMPD ID
LMP006801
Gene ID
10809
Species
Homo sapiens (Human)
Gene Name
StAR-related lipid transfer (START) domain containing 10
Gene Symbol
STARD10
Synonyms
NY-CO-28; PCTP2; SDCCAG28
Alternate Names
PCTP-like protein; PCTP-L; antigen NY-CO-28; START domain containing 10; START domain-containing protein 10; stAR-related lipid transfer protein 10; serologically defined colon cancer antigen 28
Chromosome
11
Map Location
11q13

Proteins

PCTP-like protein
Refseq ID NP_006636
Protein GI 116812600
UniProt ID Q9Y365
mRNA ID NM_006645
Length 291
RefSeq Status VALIDATED
MEKLAASTEPQGPRPVLGRESVQVPDDQDFRSFRSECEAEVGWNLTYSRAGVSVWVQAVEMDRTLHKIKCRMECCDVPAETLYDVLHDIEYRKKWDSNVIETFDIARLTVNADVGYYSWRCPKPLKNRDVITLRSWLPMGADYIIMNYSVKHPKYPPRKDLVRAVSIQTGYLIQSTGPKSCVITYLAQVDPKGSLPKWVVNKSSQFLAPKAMKKMYKACLKYPEWKQKHLPHFKPWLHPEQSPLPSLALSELSVQHADSLENIDESAVAESREERMGGAGGEGSDDDTSLT

Gene Information

Entrez Gene ID
10809
Gene Name
StAR-related lipid transfer (START) domain containing 10
Gene Symbol
STARD10
Species
Homo sapiens

Gene Ontology (GO Annotations)

GO ID Source Type Description
GO:0005829 IEA:Ensembl C cytosol
GO:0046581 IEA:Ensembl C intercellular canaliculus
GO:0016020 IEA:UniProtKB-KW C membrane
GO:0005902 IEA:Ensembl C microvillus
GO:0008289 IEA:UniProtKB-KW F lipid binding
GO:0032782 IEA:Ensembl P bile acid secretion
GO:0035360 IEA:Ensembl P positive regulation of peroxisome proliferator activated receptor signaling pathway

Domain Information

InterPro Annotations

Accession Description
IPR023393 START-like domain
IPR002913 START_lipid-bd_dom

UniProt Annotations

Entry Information

Gene Name
StAR-related lipid transfer (START) domain containing 10
Protein Entry
PCTL_HUMAN
UniProt ID
Q9Y365
Species
Human

Comments

Comment Type Description
Function May play metabolic roles in sperm maturation or fertilization (By similarity). Phospholipid transfer protein that preferentially selects lipid species containing a palmitoyl or stearoyl chain on the sn-1 and an unsaturated fatty acyl chain (18:1 or 18:2) on the sn-2 position. Able to transfer phosphatidylcholine (PC) and phosphatidyetanolamline (PE) between membranes.
Interaction Q96LA8:PRMT6; NbExp=2; IntAct=EBI-4289836, EBI-912440;
Ptm Phosphorylation at Ser-284 by CK2 negatively regulates lipid transfer activity, possibly by decreasing membrane association.
Sequence Caution Sequence=AAC18045.1; Type=Miscellaneous discrepancy; Note=Various sequencing problems as well as a translation in a wrong frame.; Evidence= ; Sequence=AAD34047.1; Type=Erroneous initiation; Evidence= ;
Similarity Contains 1 START domain. {ECO
Subcellular Location Cell projection, cilium, flagellum {ECO

Identical and Related Proteins

Unique RefSeq proteins for LMP006801 (as displayed in Record Overview)

Protein GI Database Accession Length Protein Name
116812600 RefSeq NP_006636 291 PCTP-like protein

Identical Sequences to LMP006801 proteins

Reference Database Accession Length Protein Name
GI:116812600 GenBank ADQ32095.1 291 START domain containing 10, partial [synthetic construct]
GI:116812600 GenBank ADT49071.1 291 Sequence 1088 from patent US 7842467
GI:116812600 GenBank ADT49073.1 291 Sequence 1090 from patent US 7842467
GI:116812600 GenBank ADT49075.1 291 Sequence 1092 from patent US 7842467
GI:116812600 GenBank ADT49078.1 291 Sequence 1095 from patent US 7842467
GI:116812600 GenBank AIC50723.1 291 STARD10, partial [synthetic construct]

Related Sequences to LMP006801 proteins

Reference Database Accession Length Protein Name
GI:116812600 DBBJ BAG53103.1 291 unnamed protein product [Homo sapiens]
GI:116812600 GenBank AAD34047.1 359 CGI-52 protein [Homo sapiens]
GI:116812600 GenBank ADL88055.1 359 Sequence 49 from patent US 7705120
GI:116812600 GenBank ADT49077.1 359 Sequence 1094 from patent US 7842467
GI:116812600 GenBank JAA23352.1 291 StAR-related lipid transfer (START) domain containing 10 [Pan troglodytes]
GI:116812600 GenBank JAA34150.1 291 StAR-related lipid transfer (START) domain containing 10 [Pan troglodytes]