Gene/Proteome Database (LMPD)

LMPD ID
LMP006803
Gene ID
114884
Species
Homo sapiens (Human)
Gene Name
oxysterol binding protein-like 10
Gene Symbol
OSBPL10
Synonyms
ORP10; OSBP9
Alternate Names
oxysterol-binding protein-related protein 10; ORP-10; OSBP-related protein 10
Chromosome
3
Map Location
3p22.3
Summary
This gene encodes a member of the oxysterol-binding protein (OSBP) family, a group of intracellular lipid receptors. Like most members, the encoded protein contains an N-terminal pleckstrin homology domain and a highly conserved C-terminal OSBP-like sterol-binding domain. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2010]
Orthologs
View orthologs and multiple alignments for OSBPL10

Proteins

oxysterol-binding protein-related protein 10 isoform 1
Refseq ID NP_060254
Protein GI 19923812
UniProt ID Q9BXB5
mRNA ID NM_017784
Length 764
RefSeq Status REVIEWED
MERAVQGTDGGGGSNSSSRSSSRATSAGSSPSCSLAGRGVSSRSAAAGLGGGGSRSSPGSVAASPSGGGGRRREPALEGVLSKYTNLLQGWQNRYFVLDFEAGILQYFVNEQSKHQKPRGVLSLSGAIVSLSDEAPHMLVVYSANGEMFKLRAADAKEKQFWVTQLRACAKYHMEMNSKSAPSSRSRSLTLLPHGTPNSASPCSQRHLSVGAPGVVTITHHKSPAAARRAKSQYSGQLHEVREMMNQVEGQQKNLVHAIESLPGSGPLTALDQDLLLLKATSAATLSCLGECLNLLQQSVHQAGQPSQKPGASENILGWHGSKSHSTEQLKNGTLGSLPSASANITWAILPNSAEDEQTSQPEPEPNSGSELVLSEDEKSDNEDKEETELGVMEDQRSIILHLISQLKLGMDLTKVVLPTFILEKRSLLEMYADFMAHPDLLLAITAGATPEERVICFVEYYLTAFHEGRKGALAKKPYNPIIGETFHCSWEVPKDRVKPKRTASRSPASCHEHPMADDPSKSYKLRFVAEQVSHHPPISCFYCECEEKRLCVNTHVWTKSKFMGMSVGVSMIGEGVLRLLEHGEEYVFTLPSAYARSILTIPWVELGGKVSINCAKTGYSATVIFHTKPFYGGKVHRVTAEVKHNPTNTIVCKAHGEWNGTLEFTYNNGETKVIDTTTLPVYPKKIRPLEKQGPMESRNLWREVTRYLRLGDIDAATEQKRHLEEKQRVEERKRENLRTPWKPKYFIQEGDGWVYFNPLWKAH
oxysterol-binding protein-related protein 10 isoform 2
Refseq ID NP_001167531
Protein GI 291327480
UniProt ID Q9BXB5
mRNA ID NM_001174060
Length 700
RefSeq Status REVIEWED
MERAVQGTDGGGGSNSSSRSSSRATSAGSSPSCSLAGRGVSSRSAAAGLGGGGSRSSPGSVAASPSGGGGRRREPALEGVLSKYTNLLQGWQNRYFVLDFEAGILQYFVNEQSKHQKPRGVLSLSGAIVSLSDEAPHMLVVYSANGEMFKLRAADAKEKQFWVTQLRACAKYHMEMNSKMMNQVEGQQKNLVHAIESLPGSGPLTALDQDLLLLKATSAATLSCLGECLNLLQQSVHQAGQPSQKPGASENILGWHGSKSHSTEQLKNGTLGSLPSASANITWAILPNSAEDEQTSQPEPEPNSGSELVLSEDEKSDNEDKEETELGVMEDQRSIILHLISQLKLGMDLTKVVLPTFILEKRSLLEMYADFMAHPDLLLAITAGATPEERVICFVEYYLTAFHEGRKGALAKKPYNPIIGETFHCSWEVPKDRVKPKRTASRSPASCHEHPMADDPSKSYKLRFVAEQVSHHPPISCFYCECEEKRLCVNTHVWTKSKFMGMSVGVSMIGEGVLRLLEHGEEYVFTLPSAYARSILTIPWVELGGKVSINCAKTGYSATVIFHTKPFYGGKVHRVTAEVKHNPTNTIVCKAHGEWNGTLEFTYNNGETKVIDTTTLPVYPKKIRPLEKQGPMESRNLWREVTRYLRLGDIDAATEQKRHLEEKQRVEERKRENLRTPWKPKYFIQEGDGWVYFNPLWKAH

Gene Information

Entrez Gene ID
114884
Gene Name
oxysterol binding protein-like 10
Gene Symbol
OSBPL10
Species
Homo sapiens

Gene Ontology (GO Annotations)

GO ID Source Type Description
GO:0015485 IDA:BHF-UCL F cholesterol binding
GO:0006869 IEA:UniProtKB-KW P lipid transport

Domain Information

InterPro Annotations

Accession Description
IPR000648 Oxysterol-binding protein
IPR018494 Oxysterol-binding protein, conserved site
IPR001849 Pleckstrin homology domain
IPR011993 Pleckstrin homology-like domain

UniProt Annotations

Entry Information

Gene Name
oxysterol binding protein-like 10
Protein Entry
OSB10_HUMAN
UniProt ID
Q9BXB5
Species
Human

Comments

Comment Type Description
Alternative Products Event=Alternative splicing; Named isoforms=2; Name=1; IsoId=Q9BXB5-1; Sequence=Displayed; Name=2; IsoId=Q9BXB5-2; Sequence=VSP_042930; Note=No experimental confirmation available.;
Similarity Belongs to the OSBP family.
Similarity Contains 1 PH domain. {ECO

Identical and Related Proteins

Unique RefSeq proteins for LMP006803 (as displayed in Record Overview)

Protein GI Database Accession Length Protein Name
19923812 RefSeq NP_060254 764 oxysterol-binding protein-related protein 10 isoform 1
291327480 RefSeq NP_001167531 700 oxysterol-binding protein-related protein 10 isoform 2

Identical Sequences to LMP006803 proteins

Reference Database Accession Length Protein Name
GI:291327480 DBBJ BAG64974.1 700 unnamed protein product [Homo sapiens]
GI:19923812 GenBank AAL40664.1 764 oxysterol-binding protein-like protein OSBPL10 [Homo sapiens]
GI:19923812 GenBank AAH03168.2 764 Oxysterol binding protein-like 10 [Homo sapiens]
GI:19923812 GenBank EAW64418.1 764 oxysterol binding protein-like 10, isoform CRA_b [Homo sapiens]
GI:19923812 GenBank AHE03247.1 764 Sequence 63335 from patent US 8586006
GI:19923812 SwissProt Q9BXB5.2 764 RecName: Full=Oxysterol-binding protein-related protein 10; Short=ORP-10; Short=OSBP-related protein 10 [Homo sapiens]

Related Sequences to LMP006803 proteins

Reference Database Accession Length Protein Name
GI:19923812 DBBJ BAG53477.1 764 unnamed protein product [Homo sapiens]
GI:19923812 GenBank ABP29383.1 764 Sequence 4398 from patent US 7193069
GI:19923812 GenBank JAA01689.1 764 oxysterol binding protein-like 10 [Pan troglodytes]
GI:19923812 GenBank JAA24398.1 764 oxysterol binding protein-like 10 [Pan troglodytes]
GI:291327480 RefSeq XP_003256856.1 700 PREDICTED: oxysterol-binding protein-related protein 10 isoform 2 [Nomascus leucogenys]
GI:291327480 RefSeq XP_001167116.2 700 PREDICTED: oxysterol-binding protein-related protein 10 isoform X5 [Pan troglodytes]
GI:19923812 RefSeq XP_003950094.1 764 PREDICTED: oxysterol-binding protein-related protein 10 isoform X2 [Pan troglodytes]
GI:19923812 RefSeq XP_004087979.1 764 PREDICTED: oxysterol-binding protein-related protein 10 [Nomascus leucogenys]
GI:291327480 RefSeq XP_005264901.1 705 PREDICTED: oxysterol-binding protein-related protein 10 isoform X2 [Homo sapiens]
GI:291327480 RefSeq XP_005545612.1 700 PREDICTED: oxysterol-binding protein-related protein 10 isoform X4 [Macaca fascicularis]
GI:291327480 RefSeq XP_008007554.1 700 PREDICTED: oxysterol-binding protein-related protein 10 isoform X4 [Chlorocebus sabaeus]
GI:291327480 RefSeq XP_010352768.1 700 PREDICTED: oxysterol-binding protein-related protein 10 isoform X3 [Rhinopithecus roxellana]