Gene/Proteome Database (LMPD)

LMPD ID
LMP006807
Gene ID
83758
Species
Homo sapiens (Human)
Gene Name
retinol binding protein 5, cellular
Gene Symbol
RBP5
Synonyms
CRBP-III; CRBP3; CRBPIII
Alternate Names
retinol-binding protein 5; HRBPiso; retinol-binding protein 5, cellular; cellular retinol-binding protein III; putative cellular retinol-binding protein CRBP III
Chromosome
12
Map Location
12p13.31

Proteins

retinol-binding protein 5
Refseq ID NP_113679
Protein GI 13899352
UniProt ID P82980
mRNA ID NM_031491
Length 135
RefSeq Status PROVISIONAL
MPPNLTGYYRFVSQKNMEDYLQALNISLAVRKIALLLKPDKEIEHQGNHMTVRTLSTFRNYTVQFDVGVEFEEDLRSVDGRKCQTIVTWEEEHLVCVQKGEVPNRGWRHWLEGEMLYLELTARDAVCEQVFRKVR

Gene Information

Entrez Gene ID
83758
Gene Name
retinol binding protein 5, cellular
Gene Symbol
RBP5
Species
Homo sapiens

Gene Ontology (GO Annotations)

GO ID Source Type Description
GO:0005737 IEA:UniProtKB-KW C cytoplasm
GO:0070062 IDA:UniProt C extracellular vesicular exosome
GO:0016918 IEA:UniProtKB-KW F retinal binding
GO:0005501 TAS:UniProtKB F retinoid binding
GO:0019841 IEA:UniProtKB-KW F retinol binding
GO:0005215 IEA:InterPro F transporter activity

BIOCYC Pathway Links

BIOCYC Pathway ID Description
PWY-6872 retinoate biosynthesis I
PWY-6875 retinoate biosynthesis II
PWY-6857 retinol biosynthesis
PWY-6861 the visual cycle I (vertebrates)

Domain Information

InterPro Annotations

Accession Description
IPR012674 Calycin
IPR011038 Calycin-like
IPR000463 Cytosolic fatty-acid binding
IPR000566 Lipocalin/cytosolic fatty-acid binding domain

UniProt Annotations

Entry Information

Gene Name
retinol binding protein 5, cellular
Protein Entry
RET5_HUMAN
UniProt ID
P82980
Species
Human

Comments

Comment Type Description
Domain Forms a beta-barrel structure that accommodates hydrophobic ligands in its interior.
Function Intracellular transport of retinol.
Similarity Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family.
Subcellular Location Cytoplasm .
Tissue Specificity Higher expression in adult kidney and liver and to a lesser extent in adult and fetal spleen, adult lymph nodes and appendix, and fetal liver and kidney. Strongly decreased in hepatocellular carcinoma tissues (at protein level).

Identical and Related Proteins

Unique RefSeq proteins for LMP006807 (as displayed in Record Overview)

Protein GI Database Accession Length Protein Name
13899352 RefSeq NP_113679 135 retinol-binding protein 5

Identical Sequences to LMP006807 proteins

Reference Database Accession Length Protein Name
GI:13899352 GenBank AAH29355.1 135 Retinol binding protein 5, cellular [Homo sapiens]
GI:13899352 GenBank EAW88682.1 135 retinol binding protein 5, cellular, isoform CRA_b [Homo sapiens]
GI:13899352 GenBank ABM83539.1 135 retinol binding protein 5, cellular [synthetic construct]
GI:13899352 GenBank ABM86779.1 135 retinol binding protein 5, cellular, partial [synthetic construct]
GI:13899352 GenBank AHD78629.1 135 Sequence 26627 from patent US 8586006
GI:13899352 GenBank AIC52485.1 135 RBP5, partial [synthetic construct]

Related Sequences to LMP006807 proteins

Reference Database Accession Length Protein Name
GI:13899352 DBBJ BAD97098.1 135 retinol binding protein 5, cellular variant, partial [Homo sapiens]
GI:13899352 DBBJ BAG34916.1 135 unnamed protein product [Homo sapiens]
GI:13899352 EMBL CAC69384.1 135 unnamed protein product [Homo sapiens]
GI:13899352 GenBank AAE71660.1 135 Sequence 2 from patent US 6232291
GI:13899352 GenBank AAN21146.1 135 Sequence 2 from patent US 6413726
GI:13899352 GenBank ADS15490.1 135 Sequence 10 from patent US 7759069