LIPID MAPS

LMPD ID

LMP006824

Gene ID

Species

Saccharomyces cerevisiae S288c (Yeast (S288c))

Gene Name

Swf1p

Gene Symbol

SWF1

Synonyms

PSL10

Chromosome

IV

EC Number

2.3.1.225

Swf1p
Refseq ID	NP_010411
Protein GI	6320331
UniProt ID	Q04629
mRNA ID	NM_001180434
Length	336
MSWNLLFVLLIGFVVLILLSPVFKSTWPFSTFYRNVFQPFLVDDQKYRWKLHLVPLFYTSIYLYLVYTYHMRVESTIKNELFLLERILIVPIIILPPVALGILAMVSRAEDSKDHKSGSTEEYPYDYLLYYPAIKCSTCRIVKPARSKHCSICNRCVLVADHHCIWINNCIGKGNYLQFYLFLISNIFSMCYAFLRLWYISLNSTSTLPRAVLTLTILCGCFTIICAIFTYLQLAIVKEGMTTNEQDKWYTIQEYMREGKLVRSLDDDCPSWFFKCTEQKDDAAEPLQDQHVTFYSTNAYDHKHYNLTHYITIKDASEIPNIYDKGTFLANLTDLI

Entrez Gene ID

Gene Name

Swf1p

Gene Symbol

SWF1

Species

Saccharomyces cerevisiae S288c

GO ID	Source	Type	Description
GO:0030479	IDA:SGD	C	actin cortical patch
GO:0032432	IDA:SGD	C	actin filament bundle
GO:0005783	IEA:UniProtKB-KW	C	endoplasmic reticulum
GO:0016021	ISS:SGD	C	integral component of membrane
GO:0042175	IDA:SGD	C	nuclear outer membrane-endoplasmic reticulum membrane network
GO:0016409	IDA:UniProt	F	palmitoyltransferase activity
GO:0019706	IEA:UniProtKB-EC	F	protein-cysteine S-palmitoyltransferase activity
GO:0008270	IEA:InterPro	F	zinc ion binding
GO:0030866	IMP:SGD	P	cortical actin cytoskeleton organization
GO:0030010	IMP:SGD	P	establishment of cell polarity
GO:0018345	IDA:UniProt	P	protein palmitoylation
GO:0017157	IMP:SGD	P	regulation of exocytosis
GO:0042144	IGI:SGD	P	vacuole fusion, non-autophagic

Accession	Description
IPR001594	Zinc finger, DHHC-type, palmitoyltransferase

Gene Name

Swf1p

Protein Entry

SWF1_YEAST

UniProt ID

Species

Yeast (S288c)

Comment Type	Description
Catalytic Activity	Palmitoyl-CoA + [protein]-L-cysteine = [protein]-S-palmitoyl-L-cysteine + CoA.
Domain	The DHHC domain is required for palmitoyltransferase activity.
Function	Palmitoyltransferase that targets several endosomal SNAREs. Palmitoylates the SNAREs SNC1, SNC2, SYN8 and TLG1, at cysteine residues close to the cytoplasmic end of their transmembrane domain. May have a role in the cellular quality control of transmembrane domain-containing proteins
Function	Palmitoyltransferase that targets several endosomal SNAREs. Palmitoylates the SNAREs SNC1, SNC2, SYN8 and TLG1, at cysteine residues close to the cytoplasmic end of their transmembrane domain. May have a role in the cellular quality control of transmembrane domain-containing proteins. {ECO:0000269\|PubMed:15973437}.
Similarity	Belongs to the DHHC palmitoyltransferase family. SWF1 subfamily
Similarity	Belongs to the DHHC palmitoyltransferase family. SWF1 subfamily. {ECO:0000305}.
Similarity	Contains 1 DHHC-type zinc finger
Similarity	Contains 1 DHHC-type zinc finger. {ECO:0000255\|PROSITE-ProRule:PRU00067}.
Subcellular Location	Endoplasmic reticulum membrane {ECO:0000269\|PubMed:15973437}; Multi-pass membrane protein {ECO:0000269\|PubMed:15973437}.
Subcellular Location	Endoplasmic reticulum membrane ; Multi-pass membrane protein .