Gene/Proteome Database (LMPD)

LMPD ID
LMP006882
Gene ID
850678
Species
Saccharomyces cerevisiae S288c (Yeast (S288c))
Gene Name
bile acid-transporting ATPase YBT1
Gene Symbol
YBT1
Synonyms
BAT1
Alternate Names
bile acid-transporting ATPase YBT1
Chromosome
XII

Proteins

bile acid-transporting ATPase YBT1
Refseq ID NP_013052
Protein GI 6322980
UniProt ID P32386
mRNA ID NM_001181868
Length 1661
RefSeq Status PROVISIONAL
MHHVLNSTRPDHRFWFYDDVTQYGRTKYLNYYTPLVLLIFTVLFITYNIWKHYYYYDVLHLKQKNPIDELLYSSTDEDEQSPLINNNTITTNYVDNNCTKDALKNRHFSLEKLKSVKVNGEPHGTPEIVRRGFIEKSRIILEFFLVLSQVIIHSFILLHYVNKNPEFTQQGTITGLVEWCALFIIVSLRLANVNQNFKFINKYPGNLWSVSFINYLALFISMILPFRSIFIHHINSPISRKYYISQISINLALFLLLFFARIRNNFAIIYKTDSWITPSPEPVTSIAGFICWAWLDSFVWKAHKVSIKVKDIWGLMMQDYSFFVVKKFRYFVDHKVKRKRIFSLNLFFFFSNYLVLQCFWAFLGSVLSFIPTVLLKRILEYVEDQSSAPSNLAWFYVTVMFVGRILVAICQAQALFFGRRVCIRMKSIIISEIYTKALRRKISTNKTKPSNEDPQEINDQKSINGDEESTSSANLGAIINLMAIDAFKVSEICGYLHSFLEAFVMTVVALALLYRLLGFAAIVGVLIIVAMLPLNYKLAKYIGDLQKKNLAVTDNRIQKLNEAFQAIRIIKYFSWEENFEKDINTIRENELSLLLMRSIVWSISSFLWFVTPTIVTAASFAYYIYVQGEVLTTPVAFTALSLFTLLRDPLDRLSDMLSFVVQSKVSLDRVQDFLNENDTKKYDQLTIDPNGNRFAFENSTISWDKDNQDFKLKDLNIEFKTGKLNVVIGPTGSGKTSLLMALLGEMYLLNGKVVVPALEPRQELIVDANGTTNSIAYCSQAAWLLNDTVKNNILFNSPFNEARYKAVVEACGLKRDFEILKAGDLTEIGEKGITLSGGQKQRVSLARALYSNARHVLLDDCLSAVDSHTASWIYDNCITGPLMEDRTCILVSHNIALTLRNAELVVLLEDGRVKDQGDPIDMLQKGLFGEDELVKSSILSRANSSANLAAKSSTSLSNLPAVKEQQVSVNNNSSHFEAKKLQKSLRTEAERTEDGKLIKEETKEEGVVGLDVYKWYLKIFGGWKIVSFLASLFLIAQLLYIGQSWWVRAWASHNVIAKIIPRAQRAIAFISKKASHLIDWRGSSQISMASAENQPSSGHSTMYYLVLYLIIGFAQALLGAGKTILNFVAGINASRKIFNMILNKVLHSKIRFFDATPTGRIMNRFSKDIEAIDQELTPYIQGAFYSLIECLSTVILITFITPQFLSVAIVVSILYYFVGYFYMAGSRELKRFESISRSPIYQHFSETLVGVTTIRAFGDEGRFMQENLHKIDENNKPFFYLWVANRWLAFRIDMIGSLVIFGAGLFILFNINNLDSGMAGISLTYAISFTEGALWLVRLYSEVEMNMNSVERVKEYMEIEQEPYNEHKEIPPPQWPQDGKIEVNDLSLRYAPNLPRVIKNVSFSVDAQSKIGIVGRTGAGKSTIITALFRFLEPETGHIKIDNIDISGVDLQRLRRSITIIPQDPTLFSGTIKTNLDPYDEFSDRQIFEALKRVNLISEEQLQQGATRETSNEASSTNSENVNKFLDLSSEISEGGSNLSQGQRQLMCLARSLLRSPKIILLDEATASIDYSSDAKIQETIRKEFQGSTILTIAHRLRSVIDYDKILVMDAGEVKEYDHPYSLLLNKQSAFYSMCEHSGELDILIELAKKAFVEKLNSKKD

Gene Information

Entrez Gene ID
850678
Gene Name
bile acid-transporting ATPase YBT1
Gene Symbol
YBT1
Species
Saccharomyces cerevisiae S288c

Gene Ontology (GO Annotations)

GO ID Source Type Description
GO:0000324 IDA:SGD C fungal-type vacuole
GO:0016021 IEA:UniProtKB-KW C integral component of membrane
GO:0005524 IEA:UniProtKB-KW F ATP binding
GO:0015432 IMP:SGD F bile acid-exporting ATPase activity
GO:0015721 IMP:SGD P bile acid and bile salt transport
GO:0006816 IEA:UniProtKB-KW P calcium ion transport

Domain Information

InterPro Annotations

Accession Description
IPR003593 AAA+ ATPase domain
IPR011527 ABC transporter type 1, transmembrane domain
IPR017871 ABC transporter, conserved site
IPR003439 ABC_transporter-like
IPR027417 P-loop containing nucleoside triphosphate hydrolase

UniProt Annotations

Entry Information

Gene Name
bile acid-transporting ATPase YBT1
Protein Entry
YBT1_YEAST
UniProt ID
P32386
Species
Yeast (S288c)

Comments

Comment Type Description
Function Vacuolar class C ABC transporter which regulates the translocation of phosphatidylcholine to the vacuole lumen, the release of lumenal calcium stores, and acts as a negative regulator of vacuole fusion. Exhibits ATP-dependent bile acid transport. {ECO:0000269|PubMed:21649806, ECO:0000269|PubMed:22970809}.
Miscellaneous Present with 3000 molecules/cell in log phase SD medium. {ECO:0000269|PubMed:14562106}.
Similarity Belongs to the ABC transporter superfamily. ABCC family. Conjugate transporter (TC 3.A.1.208) subfamily. {ECO:0000305}.
Similarity Contains 2 ABC transmembrane type-1 domains. {ECO:0000255|PROSITE-ProRule:PRU00441}.
Similarity Contains 2 ABC transporter domains. {ECO:0000255|PROSITE-ProRule:PRU00434}.
Subcellular Location Vacuole membrane {ECO:0000269|PubMed:21649806, ECO:0000269|PubMed:22970809}; Multi- pass membrane protein {ECO:0000255|PROSITE-ProRule:PRU00441, ECO:0000269|PubMed:21649806, ECO:0000269|PubMed:22970809}.

Identical and Related Proteins

Unique RefSeq proteins for LMP006882 (as displayed in Record Overview)

Protein GI Database Accession Length Protein Name
6322980 RefSeq NP_013052 1661 bile acid-transporting ATPase YBT1

Identical Sequences to LMP006882 proteins

Reference Database Accession Length Protein Name
GI:6322980 EMBL CAW45340.1 1661 unnamed protein product [Saccharomyces cerevisiae]
GI:6322980 EMBL CBC10843.1 1661 unnamed protein product [Saccharomyces cerevisiae]
GI:6322980 GenBank ABZ48356.1 1661 Sequence 22294 from patent US 7314974
GI:6322980 GenBank EWG94583.1 1661 Ybt1p [Saccharomyces cerevisiae R103]
GI:6322980 SwissProt P32386.2 1661 RecName: Full=ATP-dependent bile acid permease [Saccharomyces cerevisiae S288c]
GI:6322980 Third Party Genbank DAA09276.1 1661 TPA: bile acid-transporting ATPase YBT1 [Saccharomyces cerevisiae S288c]

Related Sequences to LMP006882 proteins

Reference Database Accession Length Protein Name
GI:6322980 DBBJ GAA24844.1 1661 K7_Ybt1p [Saccharomyces cerevisiae Kyokai no. 7]
GI:6322980 EMBL CAY81193.1 1661 Ybt1p [Saccharomyces cerevisiae EC1118]
GI:6322980 GenBank EDN59503.1 1661 bile transporter [Saccharomyces cerevisiae YJM789]
GI:6322980 GenBank EEU07678.1 1661 Ybt1p [Saccharomyces cerevisiae JAY291]
GI:6322980 GenBank EWH17139.1 1661 Ybt1p [Saccharomyces cerevisiae P283]
GI:6322980 gnl McCuskerlabDuke 1661 Ybt1p [Saccharomyces cerevisiae YJM993]