Gene/Proteome Database (LMPD)

LMPD ID
LMP006905
Gene ID
Species
Saccharomyces cerevisiae S288c (Yeast (S288c))
Gene Name
Smp3p
Gene Symbol
Synonyms
LAS2; SAP2
Chromosome
XV
EC Number
2.4.1.-

Proteins

Smp3p
Refseq ID NP_014792
Protein GI 398365405
UniProt ID Q04174
mRNA ID NM_001183568
Length 516
MMRYQWWLYLVYAIGLMLCLGPSYIHPDEHFQCIEILAMQFMKVKGTIPWEFKSKFAARSYGPLLLVYGPLFTILESFPEIQDNPALILYSMRLQNYVMYLLCYHFLIPKLIRDERKAVQFIKKSLLLTSYVTWTYQTHTFSNSIETLALISTLTVMEDMVNEKNIQRSNFKNSVILGLIFSFGVFNRVTFPAFIFLPCLILFWKFYRVHWKSFSLLLLSFSFSSCLFVLIDTNIYNNGKGFVITPLNNLKYNLNVQNLQVHGLHPRYTHLLVNLPQIVGPVLLLAIFSGYKLDKLSTYAIISGLLFLSFFQHQELRFLVPLVPLLVTNLNWTPLSSTLVNKKIFKGTWLLFNIIMAFIMGISHQAGIIQFLGDYFHFRTEQMGVHIWWKTYSPPTWMYMSNNLTVSSLINTQDGIESIDEVAFSVGNHHVIDLKGCDLPLLTETIRRLRLNGSITPLTLVTPNSMTSELKKLKRDGTINLIPKRNYLFHLDLDHLDFNDFTTFKPGLTVYSIELL

Gene Information

Entrez Gene ID
Gene Name
Smp3p
Gene Symbol
Species
Saccharomyces cerevisiae S288c

Gene Ontology (GO Annotations)

GO ID Source Type Description
GO:0005783 TAS:SGD C endoplasmic reticulum
GO:0016021 IEA:UniProtKB-KW C integral component of membrane
GO:0004584 IMP:SGD F dolichyl-phosphate-mannose-glycolipid alpha-mannosyltransferase activity
GO:0006506 IMP:SGD P GPI anchor biosynthetic process
GO:0097502 IMP:GOC P mannosylation
GO:0006276 IMP:SGD P plasmid maintenance

KEGG Pathway Links

KEGG Pathway ID Description
ko00563 Glycosylphosphatidylinositol(GPI)-anchor biosynthesis
sce00563 Glycosylphosphatidylinositol(GPI)-anchor biosynthesis

Domain Information

InterPro Annotations

Accession Description
IPR005599 GPI mannosyltransferase

UniProt Annotations

Entry Information

Gene Name
Smp3p
Protein Entry
SMP3_YEAST
UniProt ID
Species
Yeast (S288c)

Comments

Comment Type Description
Function Alpha-1,2-mannosyltransferase involved in glycosylphosphatidylinositol-anchor biosynthesis. Transfers a fourth mannose to trimannosyl-GPIs during GPI precursor assembly. The presence of a fourth mannose in GPI is essential in fungi. Involved in plasmid maintenance with SMP2
Function Alpha-1,2-mannosyltransferase involved in glycosylphosphatidylinositol-anchor biosynthesis. Transfers a fourth mannose to trimannosyl-GPIs during GPI precursor assembly. The presence of a fourth mannose in GPI is essential in fungi. Involved in plasmid maintenance with SMP2. {ECO:0000269|PubMed:11356840}.
Interaction P36156:ECM4; NbExp=1; IntAct=EBI-2089413, EBI-2042717;
Pathway Glycolipid biosynthesis; glycosylphosphatidylinositol- anchor biosynthesis.
Similarity Belongs to the glycosyltransferase 22 family. PIGZ subfamily
Similarity Belongs to the glycosyltransferase 22 family. PIGZ subfamily. {ECO:0000305}.
Subcellular Location Endoplasmic reticulum membrane {ECO:0000305}; Multi-pass membrane protein .
Subcellular Location Endoplasmic reticulum membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000305}.

Identical and Related Proteins

Unique RefSeq proteins for LMP006905 (as displayed in Record Overview)

Protein GI Database Accession Length Protein Name
398365405 RefSeq NP_014792 516 Smp3p

Identical Sequences to LMP006905 proteins

Reference Database Accession Length Protein Name

Related Sequences to LMP006905 proteins

Reference Database Accession Length Protein Name