Gene/Proteome Database (LMPD)

LMPD ID
LMP006913
Gene ID
856823
Species
Saccharomyces cerevisiae S288c (Yeast (S288c))
Gene Name
type 2C protein phosphatase PTC2
Gene Symbol
PTC2
Synonyms
-
Chromosome
V
EC Number
3.1.3.16;

Proteins

type 2C protein phosphatase PTC2
Refseq ID NP_011013
Protein GI 6320934
UniProt ID P39966
mRNA ID NM_001178980
Length 464
MGQILSNPVIDKESHSGADSLTAFGLCAMQGWRMSMEDSHILEPNVLTKSDKDHIAFYGIFDGHGGAKVAEYCGNKIVEILQEQKSFHEGNLPRALIDTFINTDVKLLQDPVMKEDHSGCTATSILVSKSQNLLVCGNAGDSRTVLATDGNAKALSYDHKPTLASEKSRIVAADGFVEMDRVNGNLALSRAIGDFEFKSNPKLGPEEQIVTCVPDILEHSLDYDRDEFVILACDGIWDCLTSQDCVDLVHLGLREGKTLNEISSRIIDVCCAPTTEGTGIGCDNMSIVVVALLKEGEDVAQWSDRMKSKAHRTSVRSFADKRRRVFSYYDFSKCNDEQVFAITTKKPQDKFTRDHEAAVASVTAADNDDPMDIDDTDADTDAENLDPSSQSKSKTSGPIDLASLEALLGATGGVKTDSNGNKVTYTLPQSALAQLLQTMGHDPASSHPENDSNTDHKAGRSHLQ

Gene Information

Entrez Gene ID
856823
Gene Name
type 2C protein phosphatase PTC2
Gene Symbol
PTC2
Species
Saccharomyces cerevisiae S288c

Gene Ontology (GO Annotations)

GO ID Source Type Description
GO:0046872 IEA:UniProtKB-KW F metal ion binding
GO:0004722 IDA:SGD F protein serine/threonine phosphatase activity
GO:0000077 IGI:SGD P DNA damage checkpoint
GO:0030968 IMP:SGD P endoplasmic reticulum unfolded protein response
GO:0000173 IDA:SGD P inactivation of MAPK activity involved in osmosensory signaling pathway
GO:0006470 IDA:SGD P protein dephosphorylation
GO:0000079 IMP:SGD P regulation of cyclin-dependent protein serine/threonine kinase activity

Domain Information

InterPro Annotations

Accession Description
IPR015655 Protein phosphatase 2C
IPR001932 Protein phosphatase 2C (PP2C)-like domain
IPR000222 Protein phosphatase 2C, manganese/magnesium aspartate binding site

UniProt Annotations

Entry Information

Gene Name
type 2C protein phosphatase PTC2
Protein Entry
PP2C2_YEAST
UniProt ID
P39966
Species
Yeast (S288c)

Comments

Comment Type Description
Catalytic Activity [a protein]-serine/threonine phosphate + H(2)O = [a protein]-serine/threonine + phosphate.
Cofactor Name=Mg(2+); Xref=ChEBI:CHEBI:18420; Evidence= ; Name=Mn(2+); Xref=ChEBI:CHEBI:29035; Evidence= ; Note=Binds 2 magnesium or manganese ions per subunit. ;
Cofactor Name=Mg(2+); Xref=ChEBI:CHEBI:18420; Evidence={ECO:0000250}; Name=Mn(2+); Xref=ChEBI:CHEBI:29035; Evidence={ECO:0000250}; Note=Binds 2 magnesium or manganese ions per subunit. {ECO:0000250};
Function Responsible, together with PTC3, for the dephosphorylation of the cyclin-dependent protein kinase CDC28
Function Responsible, together with PTC3, for the dephosphorylation of the cyclin-dependent protein kinase CDC28. {ECO:0000269|PubMed:10580002}.
Interaction Q12447:PAA1; NbExp=7; IntAct=EBI-12795, EBI-33397;
Miscellaneous Present with 12600 molecules/cell in log phase SD medium
Miscellaneous Present with 12600 molecules/cell in log phase SD medium. {ECO:0000269|PubMed:14562106}.
Similarity Belongs to the PP2C family
Similarity Belongs to the PP2C family. {ECO:0000305}.

Identical and Related Proteins

Unique RefSeq proteins for LMP006913 (as displayed in Record Overview)

Protein GI Database Accession Length Protein Name
6320934 RefSeq NP_011013 464 type 2C protein phosphatase PTC2

Identical Sequences to LMP006913 proteins

Reference Database Accession Length Protein Name

Related Sequences to LMP006913 proteins

Reference Database Accession Length Protein Name