Gene/Proteome Database (LMPD)

LMPD ID
LMP006920
Gene ID
856029
Species
Saccharomyces cerevisiae S288c (Yeast (S288c))
Gene Name
Gpi2p
Gene Symbol
GPI2
Synonyms
GCR4
Alternate Names
Gpi2p
Chromosome
XVI
EC Number
2.4.1.198

Proteins

Gpi2p
Refseq ID NP_015249
Protein GI 6325181
UniProt ID P46961
mRNA ID NM_001183890
Length 280
RefSeq Status PROVISIONAL
MTRSPWKRLLWLKQEYPDNYTDPSFIELRARQKAESNQKSDRKLSEAARAQIRLDFISFYQTILNTSFIYITFTYIYYYGFDPIPPTIFLSFITLIISRTKVDPLLSSFMDVKSSLIITFAMLTLSPVLKSLSKTTASDSIWTLSFWLTLWYIFVISSTKSKDKPSNLSTNILVALVAVLSSRLSTTIDVFCFLLICIQLNIILPTYLSVTNKVVPIISNIIVYSFLNVALGWIYMLLIFFASVFYITVLPKWFIYWKINYHKRDNDLLSTWDARTPILD

Gene Information

Entrez Gene ID
856029
Gene Name
Gpi2p
Gene Symbol
GPI2
Species
Saccharomyces cerevisiae S288c

Gene Ontology (GO Annotations)

GO ID Source Type Description
GO:0000506 IPI:SGD C glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex
GO:0016021 ISM:SGD C integral component of membrane
GO:0017176 ISA:SGD F phosphatidylinositol N-acetylglucosaminyltransferase activity
GO:0006506 IDA:SGD P GPI anchor biosynthetic process

KEGG Pathway Links

KEGG Pathway ID Description
ko00563 Glycosylphosphatidylinositol(GPI)-anchor biosynthesis
sce00563 Glycosylphosphatidylinositol(GPI)-anchor biosynthesis
sce01100 Metabolic pathways

Domain Information

InterPro Annotations

Accession Description
IPR009450 Phosphatidylinositol N-acetylglucosaminyltransferase subunit C

UniProt Annotations

Entry Information

Gene Name
Gpi2p
Protein Entry
GPI2_YEAST
UniProt ID
P46961
Species
Yeast (S288c)

Comments

Comment Type Description
Catalytic Activity UDP-N-acetyl-D-glucosamine + 1-phosphatidyl- 1D-myo-inositol = UDP + 6-(N-acetyl-alpha-D-glucosaminyl)-1- phosphatidyl-1D-myo-inositol.
Function Part of the complex catalyzing the transfer of N- acetylglucosamine from UDP-N-acetylglucosamine to phosphatidylinositol, the first step of GPI biosynthesis.
Interaction P62651:ERI1; NbExp=1; IntAct=EBI-7809, EBI-975247; Q04082:GPI19; NbExp=1; IntAct=EBI-7809, EBI-36611; P01120:RAS2; NbExp=1; IntAct=EBI-7809, EBI-14838;
Pathway Glycolipid biosynthesis; glycosylphosphatidylinositol- anchor biosynthesis.
Similarity Belongs to the PIGC family. {ECO:0000305}.
Subcellular Location Membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000305}.
Subunit Component of a complex with GPI1, GPI2, GPI3, GPI15 and ERI1 (Probable). Interacts with ERI1. {ECO:0000269|PubMed:15163411, ECO:0000305}.

Identical and Related Proteins

Unique RefSeq proteins for LMP006920 (as displayed in Record Overview)

Protein GI Database Accession Length Protein Name
6325181 RefSeq NP_015249 280 Gpi2p

Identical Sequences to LMP006920 proteins

Reference Database Accession Length Protein Name
GI:6325181 GenBank AFQ84257.1 280 Sequence 23 from patent US 8252294
GI:6325181 GenBank EWG82735.1 280 Gpi2p [Saccharomyces cerevisiae R008]
GI:6325181 GenBank EWG88088.1 280 Gpi2p [Saccharomyces cerevisiae P301]
GI:6325181 GenBank EWG92842.1 280 Gpi2p [Saccharomyces cerevisiae R103]
GI:6325181 GenBank EWH15424.1 280 Gpi2p [Saccharomyces cerevisiae P283]
GI:6325181 gnl McCuskerlabDuke 280 Gpi2p [Saccharomyces cerevisiae YJM993]

Related Sequences to LMP006920 proteins

Reference Database Accession Length Protein Name
GI:6325181 DBBJ GAA26898.1 280 K7_Gpi2p [Saccharomyces cerevisiae Kyokai no. 7]
GI:6325181 GenBank AAE31889.1 268 Sequence 3 from patent US 5968742
GI:6325181 GenBank EGA60290.1 280 Gpi2p [Saccharomyces cerevisiae FostersO]
GI:6325181 GenBank EHM99915.1 281 Gpi2p [Saccharomyces cerevisiae x Saccharomyces kudriavzevii VIN7]
GI:6325181 GenBank EJT41485.1 281 GPI2-like protein [Saccharomyces kudriavzevii IFO 1802]
GI:6325181 pat US 280 Sequence 2 from patent US 5667989