Gene/Proteome Database (LMPD)

LMPD ID
LMP006986
Gene ID
856287
Species
Saccharomyces cerevisiae S288c (Yeast (S288c))
Gene Name
beta-glucan synthesis-associated protein KRE6
Gene Symbol
KRE6
Synonyms
CWH48
Alternate Names
beta-glucan synthesis-associated protein KRE6
Chromosome
XVI

Proteins

beta-glucan synthesis-associated protein KRE6
Refseq ID NP_015485
Protein GI 6325417
UniProt ID P32486
mRNA ID NM_001184256
Length 720
RefSeq Status PROVISIONAL
MPLRNLTETHNFSSTNLDTDGTGDDHDGAPLSSSPSFGQQNDNSTNDNAGLTNPFMGSDEESNARDGESLSSSVHYQPQGSDSSLLHDNSRLDLSQNKGVSDYKGYYSRNNSRAVSTANDNSFLQPPHRAIASSPSLNSNLSKNDILSPPEFDRYPLVGSRVTSMTQLNHHGRSPTSSPGNESSASFSSNPFLGEQDFSPFGGYPASSFPLMIDEKEEDDYLHNPDPEEEARLDRRRFIDDFKYMDKRSASGLAGVLLLFLAAIFIFIVLPALTFTGAIDHESNTEEVTYLTQYQYPQLSAIRTSLVDPDTPDTAKTREAMDGSKWELVFSDEFNAEGRTFYDGDDPYWTAPDVHYDATKDLEWYSPDASTTVNGTLQLRMDAFKNHGLYYRSGMLQSWNKVCFTQGALEISANLPNYGRVSGLWPGLWTMGNLGRPGYLASTQGVWPYSYESCDAGITPNQSSPDGISYLPGQKLSICTCDGEDHPNQGVGRGAPEIDVLEGETDTKIGVGIASQSLQIAPFDIWYMPDYDFIEVYNFTTTTMNTYAGGPFQQAVSAVSTLNVTWYEFGEYGGYFQKYAIEYLNDDDNGYIRWFVGDTPTYTIHAKALHPDGNIGWRRISKEPMSIILNLGISNNWAYIDWQYIFFPVVMSIDYVRIYQPSNAISVTCDPSDYPTYDYIQSHLNAFQNANLTTWEDAGYTFPKNILTGKCTSSKFKLSS

Gene Information

Entrez Gene ID
856287
Gene Name
beta-glucan synthesis-associated protein KRE6
Gene Symbol
KRE6
Species
Saccharomyces cerevisiae S288c

Gene Ontology (GO Annotations)

GO ID Source Type Description
GO:0005794 IEA:UniProtKB-KW C Golgi apparatus
GO:0030176 IDA:SGD C integral component of endoplasmic reticulum membrane
GO:0016021 IDA:SGD C integral component of membrane
GO:0005886 IDA:SGD C plasma membrane
GO:0030427 IDA:SGD C site of polarized growth
GO:0030133 IDA:SGD C transport vesicle
GO:0015926 IMP:SGD F glucosidase activity
GO:0006078 IMP:SGD P (1->6)-beta-D-glucan biosynthetic process
GO:0031505 IMP:SGD P fungal-type cell wall organization

Domain Information

InterPro Annotations

Accession Description
IPR005629 Beta-glucan synthesis-associated, SKN1
IPR013320 Concanavalin A-like lectin/glucanase domain

UniProt Annotations

Entry Information

Gene Name
beta-glucan synthesis-associated protein KRE6
Protein Entry
KRE6_YEAST
UniProt ID
P32486
Species
Yeast (S288c)

Comments

Comment Type Description
Function Involved in the synthesis of (1->6)- and (1->3)-beta-D- glucan polymers of the yeast cell wall in vivo. It is required for full activity of beta-glucan synthase in vitro. May be involved in the maturation and transport of cell wall proteins (CWP) to the cell wall. May act as a transglucosidase and contribute to the construction of a protein-bound glucan-structure that acts as an acceptor site for the addition of (1->6)-beta-D-glucan at the cell surface. {ECO:0000269|PubMed:10601196, ECO:0000269|PubMed:12237851, ECO:0000269|PubMed:15093776}.
Miscellaneous Present with 4760 molecules/cell in log phase SD medium. {ECO:0000269|PubMed:14562106}.
Similarity Belongs to the SKN1/KRE6 family. {ECO:0000305}.
Subcellular Location Golgi apparatus membrane {ECO:0000269|PubMed:12237851}; Single-pass type II membrane protein {ECO:0000269|PubMed:12237851}.
Subunit The cytoplasmic domain interacts with the actin patch assembly proteins LAS17 and SLA1. Interacts with KEG1. {ECO:0000269|PubMed:12237851, ECO:0000269|PubMed:17893149}.

Identical and Related Proteins

Unique RefSeq proteins for LMP006986 (as displayed in Record Overview)

Protein GI Database Accession Length Protein Name
6325417 RefSeq NP_015485 720 beta-glucan synthesis-associated protein KRE6

Identical Sequences to LMP006986 proteins

Reference Database Accession Length Protein Name
GI:6325417 GenBank EGA76501.1 720 Kre6p [Saccharomyces cerevisiae Vin13]
GI:6325417 GenBank EIW07263.1 720 Kre6p [Saccharomyces cerevisiae CEN.PK113-7D]
GI:6325417 GenBank EWG82931.1 720 Kre6p [Saccharomyces cerevisiae R008]
GI:6325417 GenBank EWG88262.1 720 Kre6p [Saccharomyces cerevisiae P301]
GI:6325417 GenBank EWG92793.1 720 Kre6p [Saccharomyces cerevisiae R103]
GI:6325417 Third Party Genbank DAA11575.1 720 TPA: beta-glucan synthesis-associated protein KRE6 [Saccharomyces cerevisiae S288c]

Related Sequences to LMP006986 proteins

Reference Database Accession Length Protein Name
GI:6325417 GenBank EGA56425.1 720 Kre6p [Saccharomyces cerevisiae FostersB]
GI:6325417 GenBank EGA60153.1 720 Kre6p [Saccharomyces cerevisiae FostersO]
GI:6325417 GenBank EGA80643.1 720 Kre6p [Saccharomyces cerevisiae Lalvin QA23]
GI:6325417 GenBank EGA84303.1 720 Kre6p [Saccharomyces cerevisiae VL3]
GI:6325417 GenBank EHN04150.1 720 Kre6p [Saccharomyces cerevisiae x Saccharomyces kudriavzevii VIN7]
GI:6325417 gnl McCuskerlabDuke 720 Kre6p [Saccharomyces cerevisiae YJM993]