Gene/Proteome Database (LMPD)

LMPD ID
LMP006990
Gene ID
850943
Species
Saccharomyces cerevisiae S288c (Yeast (S288c))
Gene Name
Arv1p
Gene Symbol
ARV1
Synonyms
-
Alternate Names
Arv1p
Chromosome
XII

Proteins

Arv1p
Refseq ID NP_013343
Protein GI 6323271
UniProt ID Q06541
mRNA ID NM_001182129
Length 321
RefSeq Status PROVISIONAL
MICITCMRPVDSLYTVYSNDHIQLTDCPYCQETVDKYVEIDNVLLFIDLLLLKAGAYRHLVFNALELHLSKYPKRKALNDCQCLRDYTQALLFNVKNWFCKYDRLNRLWLLLLSFEIYLTWVTEESKYIYYLNRNNNDGKLIMLSKKLPESFKWDSAIMRNTITSKVFTWSPPIQYLYFASYCILDVSLFHTFTQYFILKKLHWKHYSVSSKDVISYTILLSYGAKIFPILMLIWPYDTLISMSIIKWVANLYIIESLKIVTNLSYWNIIKIFISVSLLRYFMVKPILIVFVAKFNFSVIKNLIHQEFILLLQKSGTYLLL

Gene Information

Entrez Gene ID
850943
Gene Name
Arv1p
Gene Symbol
ARV1
Species
Saccharomyces cerevisiae S288c

Gene Ontology (GO Annotations)

GO ID Source Type Description
GO:0005794 IDA:SGD C Golgi apparatus
GO:0032541 IDA:SGD C cortical endoplasmic reticulum
GO:0005783 IDA:SGD C endoplasmic reticulum
GO:0016021 IEA:UniProtKB-KW C integral component of membrane
GO:0035621 IMP:SGD P ER to Golgi ceramide transport
GO:0006506 IMP:SGD P GPI anchor biosynthetic process
GO:0006897 IMP:SGD P endocytosis
GO:0032366 IMP:SGD P intracellular sterol transport
GO:0097036 IMP:SGD P regulation of plasma membrane sterol distribution
GO:0030148 IMP:SGD P sphingolipid biosynthetic process
GO:0035376 IMP:SGD P sterol import

Domain Information

InterPro Annotations

Accession Description
IPR007290 Arv1 protein

UniProt Annotations

Entry Information

Gene Name
Arv1p
Protein Entry
ARV1_YEAST
UniProt ID
Q06541
Species
Yeast (S288c)

Comments

Comment Type Description
Function Mediator of sterol homeostasis involved in sterol uptake, trafficking and distribution into membranes. Regulates also the sphingolipid metabolism. Required for growth during anaerobiosis and sterol uptake. {ECO:0000269|PubMed:11063737, ECO:0000269|PubMed:12145310}.
Interaction Q12007:ERR1; NbExp=1; IntAct=EBI-31952, EBI-35679;
Similarity Belongs to the ARV1 family. {ECO:0000305}.
Subcellular Location Endoplasmic reticulum membrane {ECO:0000269|PubMed:12145310}; Multi-pass membrane protein {ECO:0000269|PubMed:12145310}. Golgi apparatus membrane {ECO:0000269|PubMed:12145310}; Multi-pass membrane protein {ECO:0000269|PubMed:12145310}.

Identical and Related Proteins

Unique RefSeq proteins for LMP006990 (as displayed in Record Overview)

Protein GI Database Accession Length Protein Name
6323271 RefSeq NP_013343 321 Arv1p

Identical Sequences to LMP006990 proteins

Reference Database Accession Length Protein Name
GI:6323271 DBBJ GAA25111.1 321 K7_Arv1p [Saccharomyces cerevisiae Kyokai no. 7]
GI:6323271 GenBank EWG84475.1 321 Arv1p [Saccharomyces cerevisiae R008]
GI:6323271 GenBank EWG89641.1 321 Arv1p [Saccharomyces cerevisiae P301]
GI:6323271 GenBank EWG94406.1 321 Arv1p [Saccharomyces cerevisiae R103]
GI:6323271 GenBank EWH17103.1 321 Arv1p [Saccharomyces cerevisiae P283]
GI:6323271 gnl McCuskerlabDuke 321 Arv1p [Saccharomyces cerevisiae YJM993]

Related Sequences to LMP006990 proteins

Reference Database Accession Length Protein Name
GI:6323271 GenBank EGA73762.1 278 Arv1p [Saccharomyces cerevisiae AWRI796]
GI:6323271 GenBank EGA77761.1 315 Arv1p [Saccharomyces cerevisiae Vin13]
GI:6323271 GenBank EGA81716.1 315 Arv1p [Saccharomyces cerevisiae Lalvin QA23]
GI:6323271 GenBank EHN05601.1 315 Arv1p [Saccharomyces cerevisiae x Saccharomyces kudriavzevii VIN7]
GI:6323271 GenBank EJS42695.1 321 arv1p [Saccharomyces arboricola H-6]
GI:6323271 GenBank EJT41799.1 321 ARV1-like protein [Saccharomyces kudriavzevii IFO 1802]