Gene/Proteome Database (LMPD)

LMPD ID
LMP006995
Gene ID
853179
Species
Saccharomyces cerevisiae S288c (Yeast (S288c))
Gene Name
Say1p
Gene Symbol
SAY1
Synonyms
-
Alternate Names
Say1p
Chromosome
VII
EC Number
3.1.1.-

Proteins

Say1p
Refseq ID NP_011779
Protein GI 398366343
UniProt ID P53324
mRNA ID NM_001181392
Length 424
RefSeq Status PROVISIONAL
MAANSGLDSKVEYYRLQENEIISAVSSEDADQNDAGFRLSTIHLHLFHGLKFAALLFTVVPVFIILDSMKIIFQRKRRFCLDHVNRSFLRQSSWILDERICQYVLNPLFVCLYPSTFSSPTYVKCNIPIEDQKSPENNIFQDHQLNAPKIVSTKFYQYVMPEGFDPTTDPVLVFYHGGGYALKLTPTSFSFLNNMRNAFPKMAILVPDYTVTATDDQSKKYPLQILQNVAIFDYVVKTMGCKNVVIMGDSAGGNAVLNIVLYLRKCHREIYPKKVIAISPWANATFFHEGEKEYMQGTQEWDGLCLKSHSMFGRMFVGNNPNVDFTSDPFVNIEKNFETKMWQDILKKCSVMITYGSDELLSFQNKILAKKMSDASEGCNHFTAKNVLVEHQGYHTGPILNYSRNMDRWTNIPSIARILEFMQS

Gene Information

Entrez Gene ID
853179
Gene Name
Say1p
Gene Symbol
SAY1
Species
Saccharomyces cerevisiae S288c

Gene Ontology (GO Annotations)

GO ID Source Type Description
GO:0005783 IDA:SGD C endoplasmic reticulum
GO:0005788 IDA:SGD C endoplasmic reticulum lumen
GO:0016021 IDA:SGD C integral component of membrane
GO:0005811 IDA:SGD C lipid particle
GO:0034084 IDA:SGD F steryl deacetylase activity
GO:0009636 IMP:SGD P response to toxic substance
GO:0034210 IMP:SGD P sterol deacetylation
GO:0016125 IMP:SGD P sterol metabolic process

Domain Information

InterPro Annotations

Accession Description
IPR029058 Alpha/Beta hydrolase fold
IPR019436 Steryl acetyl hydrolase

UniProt Annotations

Entry Information

Gene Name
Say1p
Protein Entry
SAY1_YEAST
UniProt ID
P53324
Species
Yeast (S288c)

Comments

Comment Type Description
Function Required for the deacetylation of acetylated sterols. Involved in the resistance to eugenol and pregnenolone toxicity. {ECO:0000269|PubMed:18034159}.
Similarity Belongs to the 'GDXG' lipolytic enzyme family. {ECO:0000305}.
Subcellular Location Endoplasmic reticulum membrane {ECO:0000269|PubMed:18034159}; Single-pass type II membrane protein {ECO:0000269|PubMed:18034159}.

Identical and Related Proteins

Unique RefSeq proteins for LMP006995 (as displayed in Record Overview)

Protein GI Database Accession Length Protein Name
398366343 RefSeq NP_011779 424 Say1p

Identical Sequences to LMP006995 proteins

Reference Database Accession Length Protein Name
GI:398366343 GenBank EDV10000.1 424 conserved hypothetical protein [Saccharomyces cerevisiae RM11-1a]
GI:398366343 GenBank EIW10612.1 424 Say1p [Saccharomyces cerevisiae CEN.PK113-7D]
GI:398366343 GenBank EWG91198.1 424 Say1p [Saccharomyces cerevisiae P301]
GI:398366343 GenBank EWH18483.1 424 Say1p [Saccharomyces cerevisiae P283]
GI:398366343 SwissProt P53324.1 424 RecName: Full=Steryl acetyl hydrolase 1 [Saccharomyces cerevisiae S288c]
GI:398366343 Third Party Genbank DAA08353.1 424 TPA: Say1p [Saccharomyces cerevisiae S288c]

Related Sequences to LMP006995 proteins

Reference Database Accession Length Protein Name
GI:398366343 EMBL CAY80021.1 424 Say1p [Saccharomyces cerevisiae EC1118]
GI:398366343 GenBank EDZ71894.1 424 YGR263Cp-like protein [Saccharomyces cerevisiae AWRI1631]
GI:398366343 GenBank EGA74806.1 424 Say1p [Saccharomyces cerevisiae AWRI796]
GI:398366343 GenBank EWG86123.1 424 Say1p [Saccharomyces cerevisiae R008]
GI:398366343 GenBank EWG95761.1 424 Say1p [Saccharomyces cerevisiae R103]
GI:398366343 gnl McCuskerlabDuke 424 Say1p [Saccharomyces cerevisiae YJM993]