Gene/Proteome Database (LMPD)

LMPD ID
LMP007017
Gene ID
856314
Species
Saccharomyces cerevisiae S288c (Yeast (S288c))
Gene Name
bifunctional 4-alpha-glucanotransferase/amylo-alpha-1,6-glucosidase
Gene Symbol
GDB1
Synonyms
-
Alternate Names
bifunctional 4-alpha-glucanotransferase/amylo-alpha-1,6-glucosidase
Chromosome
XVI
EC Number
2.4.1.25

Proteins

bifunctional 4-alpha-glucanotransferase/amylo-alpha-1,6-glucosidase
Refseq ID NP_015510
Protein GI 6325442
UniProt ID Q06625
mRNA ID NM_001184281
Length 1536
RefSeq Status PROVISIONAL
MNRSLLLRLSDTGEPITSCSYGKGVLTLPPIPLPKDAPKDQPLYTVKLLVSAGSPVARDGLVWTNCPPDHNTPFKRDKFYKKIIHSSFHEDDCIDLNVYAPGSYCFYLSFRNDNEKLETTRKYYFVALPMLYINDQFLPLNSIALQSVVSKWLGSDWEPILSKIAAKNYNMVHFTPLQERGESNSPYSIYDQLQFDQEHFKSPEDVKNLVEHIHRDLNMLSLTDIVFNHTANNSPWLVEHPEAGYNHITAPHLISAIELDQELLNFSRNLKSWGYPTELKNIEDLFKIMDGIKVHVLGSLKLWEYYAVNVQTALRDIKAHWNDESNESYSFPENIKDISSDFVKLASFVKDNVTEPNFGTLGERNSNRINVPKFIQLLKLINDGGSDDSESSLATAQNILNEVNLPLYREYDDDVSEILEQLFNRIKYLRLDDGGPKQGPVTVDVPLTEPYFTRFKGKDGTDYALANNGWIWNGNPLVDFASQNSRAYLRREVIVWGDCVKLRYGKSPEDSPYLWERMSKYIEMNAKIFDGFRIDNCHSTPIHVGEYFLDLARKYNPNLYVVAELFSGSETLDCLFVERLGISSLIREAMQAWSEEELSRLVHKHGGRPIGSYKFVPMDDFSYPADINLNEEHCFNDSNDNSIRCVSEIMIPKILTATPPHALFMDCTHDNETPFEKRTVEDTLPNAALVALCSSAIGSVYGYDEIFPHLLNLVTEKRHYDISTPTGSPSIGITKVKATLNSIRTSIGEKAYDIEDSEMHVHHQGQYITFHRMDVKSGKGWYLIARMKFSDNDDPNETLPPVVLNQSTCSLRFSYALERVGDEIPNDDKFIKGIPTKLKELEGFDISYDDSKKISTIKLPNEFPQGSIAIFETQQNGVDESLDHFIRSGALKATSSLTLESINSVLYRSEPEEYDVSAGEGGAYIIPNFGKPVYCGLQGWVSVLRKIVFYNDLAHPLSANLRNGHWALDYTISRLNYYSDEAGINEVQNWLRSRFDRVKKLPSYLVPSYFALIIGILYGCCRLKAIQLMSRNIGKSTLFVQSLSMTSIQMVSRMKSTSILPGENVPSMAAGLPHFSVNYMRCWGRDVFISLRGMLLTTGRFDEAKAHILAFAKTLKHGLIPNLLDAGRNPRYNARDAAWFFLQAVQDYVYIVPDGEKILQEQVTRRFPLDDTYIPVDDPRAFSYSSTLEEIIYEILSRHAKGIKFREANAGPNLDRVMTDKGFNVEIHVDWSTGLIHGGSQYNCGTWMDKMGESEKAGSVGIPGTPRDGAAIEINGLLKSALRFVIELKNKGLFKFSDVETQDGGRIDFTEWNQLLQDNFEKRYYVPEDPSQDADYDVSAKLGVNRRGIYRDLYKSGKPYEDYQLRPNFAIAMTVAPELFVPEHAIKAITIADEVLRGPVGMRTLDPSDYNYRPYYNNGEDSDDFATSKGRNYHQGPEWVWLYGYFLRAFHHFHFKTSPRCQNAAKEKPSSYLYQQLYYRLKGHRKWIFESVWAGLTELTNKDGEVCNDSSPTQAWSSACLLDLFYDLWDAYEDDS

Gene Information

Entrez Gene ID
856314
Gene Name
bifunctional 4-alpha-glucanotransferase/amylo-alpha-1,6-glucosidase
Gene Symbol
GDB1
Species
Saccharomyces cerevisiae S288c

Gene Ontology (GO Annotations)

GO ID Source Type Description
GO:0005739 IEA:UniProtKB-KW C mitochondrion
GO:0004134 IDA:SGD F 4-alpha-glucanotransferase activity
GO:0004135 IDA:SGD F amylo-alpha-1,6-glucosidase activity
GO:0005978 IEA:UniProtKB-KW P glycogen biosynthetic process
GO:0005980 IMP:SGD P glycogen catabolic process

KEGG Pathway Links

KEGG Pathway ID Description
sce01100 Metabolic pathways

BIOCYC Pathway Links

BIOCYC Pathway ID Description
GLYCOCAT-PWY glycogen degradation

REACTOME Pathway Links

REACTOME Pathway ID Description
5618038 Glycogen breakdown (glycogenolysis)

Domain Information

InterPro Annotations

Accession Description
IPR029436 Eukaryotic glycogen debranching enzyme, N-terminal domain
IPR010401 Glycogen debranching enzyme
IPR006421 Glycogen debranching enzyme, metazoa
IPR013781 Glycoside hydrolase, catalytic domain
IPR017853 Glycoside hydrolase superfamily
IPR008928 Six-hairpin glycosidase-like

UniProt Annotations

Entry Information

Gene Name
bifunctional 4-alpha-glucanotransferase/amylo-alpha-1,6-glucosidase
Protein Entry
GDE_YEAST
UniProt ID
Q06625
Species
Yeast (S288c)

Comments

Comment Type Description
Catalytic Activity Hydrolysis of (1->6)-alpha-D-glucosidic branch linkages in glycogen phosphorylase limit dextrin.
Catalytic Activity Transfers a segment of a (1->4)-alpha-D-glucan to a new position in an acceptor, which may be glucose or a (1->4)-alpha-D-glucan.
Enzyme Regulation Activity is inhibited by IGD1. {ECO:0000269|PubMed:21585652}.
Function Multifunctional enzyme acting as 1,4-alpha-D-glucan:1,4- alpha-D-glucan 4-alpha-D-glycosyltransferase and amylo-1,6- glucosidase in glycogen degradation. {ECO:0000269|PubMed:11094287, ECO:0000269|PubMed:21585652}.
Miscellaneous Present with 125 molecules/cell in log phase SD medium. {ECO:0000269|PubMed:14562106}.
Similarity Belongs to the glycogen debranching enzyme family. {ECO:0000305}.
Subcellular Location Mitochondrion {ECO:0000269|PubMed:14562095}. Cytoplasm {ECO:0000269|PubMed:14562095}.
Subunit Interacts with IGD1. {ECO:0000269|PubMed:21585652}.

Identical and Related Proteins

Unique RefSeq proteins for LMP007017 (as displayed in Record Overview)

Protein GI Database Accession Length Protein Name
6325442 RefSeq NP_015510 1536 bifunctional 4-alpha-glucanotransferase/amylo-alpha-1,6-glucosidase

Identical Sequences to LMP007017 proteins

Reference Database Accession Length Protein Name
GI:6325442 GenBank EEU07417.1 1536 Gdb1p [Saccharomyces cerevisiae JAY291]
GI:6325442 GenBank EWG82954.1 1536 Gdb1p [Saccharomyces cerevisiae R008]
GI:6325442 GenBank EWG88287.1 1536 Gdb1p [Saccharomyces cerevisiae P301]
GI:6325442 gnl McCuskerlabDuke 1536 Gdb1p [Saccharomyces cerevisiae YJM993]
GI:6325442 SwissProt Q06625.1 1536 RecName: Full=Glycogen debranching enzyme; AltName: Full=Glycogen debrancher; Includes: RecName: Full=4-alpha-glucanotransferase; AltName: Full=Oligo-1,4-1,4-glucantransferase; Includes: RecName: Full=Amylo-alpha-1,6-glucosidase; Short=Amylo-1,6-glucosidase; AltName: Full=Dextrin 6-alpha-D-glucosidase [Saccharomyces cerevisiae S288c]
GI:6325442 Third Party Genbank DAA11600.1 1536 TPA: bifunctional 4-alpha-glucanotransferase/amylo-alpha-1,6-glucosidase [Saccharomyces cerevisiae S288c]

Related Sequences to LMP007017 proteins

Reference Database Accession Length Protein Name
GI:6325442 EMBL CAY87144.1 1536 Gdb1p [Saccharomyces cerevisiae EC1118]
GI:6325442 GenBank EDN61300.1 1536 conserved protein [Saccharomyces cerevisiae YJM789]
GI:6325442 GenBank EDV11371.1 1536 glycogen debranching enzyme (Dextrin 6-alpha-D-glucosidase) [Saccharomyces cerevisiae RM11-1a]
GI:6325442 GenBank EIW07289.1 1536 Gdb1p [Saccharomyces cerevisiae CEN.PK113-7D]
GI:6325442 GenBank EWG92816.1 1536 Gdb1p [Saccharomyces cerevisiae R103]
GI:6325442 GenBank EWH15629.1 1538 Gdb1p [Saccharomyces cerevisiae P283]