Gene/Proteome Database (LMPD)

LMPD ID
LMP007023
Gene ID
856059
Species
Saccharomyces cerevisiae S288c (Yeast (S288c))
Gene Name
Cam1p
Gene Symbol
CAM1
Synonyms
TEF3
Alternate Names
Cam1p
Chromosome
XVI

Proteins

Cam1p
Refseq ID NP_015277
Protein GI 6325209
UniProt ID P29547
mRNA ID NM_001183862
Length 415
RefSeq Status PROVISIONAL
MSQGTLYANFRIRTWVPRGLVKALKLDVKVVTPDAAAEQFARDFPLKKVPAFVGPKGYKLTEAMAINYYLVKLSQDDKMKTQLLGADDDLNAQAQIIRWQSLANSDLCIQIANTIVPLKGGAPYNKKSVDSAMDAVDKIVDIFENRLKNYTYLATENISLADLVAASIFTRYFESLFGTEWRAQHPAIVRWFNTVRASPFLKDEYKDFKFADKPLSPPQKKKEKKAPAAAPAASKKKEEAKPAATETETSSKKPKHPLELLGKSTFVLDDWKRKYSNEDTRPVALPWFWEHYNPEEYSLWKVTYKYNDELTLTFMSNNLVGGFFNRLSASTKYMFGCLVVYGENNNNGIVGAVMVRGQDYVPAFDVAPDWESYDYAKLDPTNDDDKEFINNMWAWDKPVSVNGEPKEIVDGKVLK

Gene Information

Entrez Gene ID
856059
Gene Name
Cam1p
Gene Symbol
CAM1
Species
Saccharomyces cerevisiae S288c

Gene Ontology (GO Annotations)

GO ID Source Type Description
GO:0005737 IEA:UniProtKB-KW C cytoplasm
GO:0005634 IDA:SGD C nucleus
GO:0005509 IDA:SGD F calcium ion binding
GO:0005543 IDA:SGD F phospholipid binding
GO:0003713 IMP:SGD F transcription coactivator activity
GO:0003746 IEA:UniProtKB-KW F translation elongation factor activity
GO:0045944 IMP:SGD P positive regulation of transcription from RNA polymerase II promoter
GO:0042254 IGI:SGD P ribosome biogenesis

REACTOME Pathway Links

REACTOME Pathway ID Description
5618282 Eukaryotic Translation Elongation
5618074 Metabolism of proteins
5618073 Translation

Domain Information

InterPro Annotations

Accession Description
IPR004046 Glutathione S-transferase, C-terminal
IPR010987 Glutathione S-transferase, C-terminal-like
IPR004045 Glutathione S-transferase, N-terminal
IPR012336 Thioredoxin-like fold
IPR001662 Translation elongation factor EF1B, gamma chain, conserved

UniProt Annotations

Entry Information

Gene Name
Cam1p
Protein Entry
EF1G1_YEAST
UniProt ID
P29547
Species
Yeast (S288c)

Comments

Comment Type Description
Domain Ths GST-like domain mediates the interaction to eEFB1 and may be responsible for dimerization of the eEF1 complex.
Function Subunit of the eukaryotic elongation factor 1 complex (eEF1). Probably plays a role in anchoring the complex to other cellular components. May be involved in transcriptional regulation of MXR1. {ECO:0000269|PubMed:12824466}.
Miscellaneous Present with 60865 molecules/cell in log phase SD medium. {ECO:0000269|PubMed:14562106}.
Miscellaneous There are 2 isoforms for eEF1Bgamma in yeast.
Pathway Protein biosynthesis; polypeptide chain elongation.
Similarity Contains 1 EF-1-gamma C-terminal domain. {ECO:0000255|PROSITE-ProRule:PRU00519}.
Similarity Contains 1 GST C-terminal domain. {ECO:0000305}.
Similarity Contains 1 GST N-terminal domain. {ECO:0000305}.
Subcellular Location Cytoplasm. Nucleus.
Subunit The eukaryotic elongation factor 1 complex (eEF1) is probably a heterohexamer. Two trimeric complexes, each composed of eEF1A (TEF1 or TEF2), eEF1Balpha (EFB1) and eEF1Bgamma (CAM1 or TEF4), are probably dimerized via the eF1Bgamma subunits. The eEF1B subcomplex with the GEF activity is formed of eEF1Balpha and eEF1Bgamma. CAM1 interacts with EFB1. Component of a complex bound to MXR1 promoter region. {ECO:0000269|PubMed:12972429}.

Identical and Related Proteins

Unique RefSeq proteins for LMP007023 (as displayed in Record Overview)

Protein GI Database Accession Length Protein Name
6325209 RefSeq NP_015277 415 Cam1p

Identical Sequences to LMP007023 proteins

Reference Database Accession Length Protein Name
GI:6325209 GenBank EHN04377.1 415 Cam1p [Saccharomyces cerevisiae x Saccharomyces kudriavzevii VIN7]
GI:6325209 GenBank EIW07066.1 415 Cam1p [Saccharomyces cerevisiae CEN.PK113-7D]
GI:6325209 GenBank EWG82758.1 415 Cam1p [Saccharomyces cerevisiae R008]
GI:6325209 GenBank EWG88111.1 415 Cam1p [Saccharomyces cerevisiae P301]
GI:6325209 GenBank EWG92867.1 415 Cam1p [Saccharomyces cerevisiae R103]
GI:6325209 gnl McCuskerlabDuke 415 Cam1p [Saccharomyces cerevisiae YJM993]

Related Sequences to LMP007023 proteins

Reference Database Accession Length Protein Name
GI:6325209 GenBank AAA16892.1 415 elongation growth 1-gamma [Saccharomyces cerevisiae]
GI:6325209 GenBank EGA56581.1 415 Cam1p [Saccharomyces cerevisiae FostersB]
GI:6325209 GenBank EHM99840.1 399 Cam1p [Saccharomyces cerevisiae x Saccharomyces kudriavzevii VIN7]
GI:6325209 GenBank EJS41381.1 419 cam1p [Saccharomyces arboricola H-6]
GI:6325209 GenBank EJT44729.1 399 CAM1-like protein [Saccharomyces kudriavzevii IFO 1802]
GI:6325209 GenBank EWH15445.1 415 Cam1p [Saccharomyces cerevisiae P283]