Gene/Proteome Database (LMPD)

LMPD ID
LMP007061
Gene ID
853470
Species
Saccharomyces cerevisiae S288c (Yeast (S288c))
Gene Name
Gpi14p
Gene Symbol
GPI14
Synonyms
PMH1
Alternate Names
Gpi14p
Chromosome
X
EC Number
2.4.1.-

Proteins

Gpi14p
Refseq ID NP_012547
Protein GI 42742257
UniProt ID P47088
mRNA ID NM_001181671
Length 403
RefSeq Status PROVISIONAL
MTGEEWGLTVLSFLVRVGFFLFGIYQDANFKVRYTDIDYFVFHDAAKYVYEGKSPYARDTYRYTPLLSWLLVPNHYFGWFHLGKVIFVIFDLVTGLIIMKLLNQAISRKRALILESIWLLNPMVITISTRGNAESVLCCLIMFTLFFLQKSRYTLAGILYGLSIHFKIYPIIYCIPIAIFIYYNKRNQGPRTQLTSLLNIGLSTLTTLLGCGWAMYKIYGYEFLDQAYLYHLYRTDHRHNFSVWNMLLYLDSANKENGESNLSRYAFVPQLLLVLVTGCLEWWNPTFDNLLRVLFVQTFAFVTYNKVCTSQYFVWYLIFLPFYLSRTHIGWKKGLLMATLWVGTQGIWLSQGYYLEFEGKNVFYPGLFIASVLFFVTNVWLLGQFITDIKIPTQPTVSNKKNN

Gene Information

Entrez Gene ID
853470
Gene Name
Gpi14p
Gene Symbol
GPI14
Species
Saccharomyces cerevisiae S288c

Gene Ontology (GO Annotations)

GO ID Source Type Description
GO:0005789 ISS:SGD C endoplasmic reticulum membrane
GO:0016021 IEA:UniProtKB-KW C integral component of membrane
GO:0000030 ISS:SGD F mannosyltransferase activity
GO:0006506 IMP:SGD P GPI anchor biosynthetic process
GO:0031505 IMP:SGD P fungal-type cell wall organization
GO:0097502 ISS:GOC P mannosylation

KEGG Pathway Links

KEGG Pathway ID Description
sce_M00065 GPI-anchor biosynthesis, core oligosaccharide
ko00563 Glycosylphosphatidylinositol(GPI)-anchor biosynthesis
sce00563 Glycosylphosphatidylinositol(GPI)-anchor biosynthesis
sce01100 Metabolic pathways

Domain Information

InterPro Annotations

Accession Description
IPR007704 Mannosyltransferase, DXD

UniProt Annotations

Entry Information

Gene Name
Gpi14p
Protein Entry
GPI14_YEAST
UniProt ID
P47088
Species
Yeast (S288c)

Comments

Comment Type Description
Function Mannosyltransferase involved in glycosylphosphatidylinositol-anchor biosynthesis. Transfers the first alpha-1,4-mannose to GlcN-acyl-PI during GPI precursor assembly. Required for cell wall integrity. {ECO:0000269|PubMed:16134120}.
Pathway Glycolipid biosynthesis; glycosylphosphatidylinositol- anchor biosynthesis.
Sequence Caution Sequence=CAA60935.1; Type=Frameshift; Positions=40; Evidence={ECO:0000305}; Sequence=CAA89537.1; Type=Frameshift; Positions=40; Evidence={ECO:0000305};
Similarity Belongs to the PIGM family. {ECO:0000305}.
Subcellular Location Endoplasmic reticulum membrane {ECO:0000269|PubMed:14562095}; Multi-pass membrane protein {ECO:0000269|PubMed:14562095}.

Identical and Related Proteins

Unique RefSeq proteins for LMP007061 (as displayed in Record Overview)

Protein GI Database Accession Length Protein Name
42742257 RefSeq NP_012547 403 Gpi14p

Identical Sequences to LMP007061 proteins

Reference Database Accession Length Protein Name
GI:42742257 DBBJ GAA24368.1 403 K7_Gpi14p [Saccharomyces cerevisiae Kyokai no. 7]
GI:42742257 GenBank EIW09541.1 403 Gpi14p [Saccharomyces cerevisiae CEN.PK113-7D]
GI:42742257 SwissProt P47088.2 403 RecName: Full=GPI mannosyltransferase 1; AltName: Full=GPI mannosyltransferase I; Short=GPI-MT-I; AltName: Full=Glycosylphosphatidylinositol-anchor biosynthesis protein 14 [Saccharomyces cerevisiae S288c]
GI:42742257 Third Party Genbank DAA08805.1 403 TPA: Gpi14p [Saccharomyces cerevisiae S288c]

Related Sequences to LMP007061 proteins

Reference Database Accession Length Protein Name
GI:42742257 EMBL CBK33741.1 403 Gpi14p [Saccharomyces cerevisiae EC1118]
GI:42742257 GenBank EDV12765.1 403 conserved hypothetical protein [Saccharomyces cerevisiae RM11-1a]
GI:42742257 GenBank EEU04814.1 403 Gpi14p [Saccharomyces cerevisiae JAY291]
GI:42742257 GenBank EGA74247.1 403 Gpi14p [Saccharomyces cerevisiae AWRI796]
GI:42742257 GenBank EWG95125.1 403 Gpi14p [Saccharomyces cerevisiae R103]
GI:42742257 gnl McCuskerlabDuke 403 Gpi14p [Saccharomyces cerevisiae YJM993]