Gene/Proteome Database (LMPD)

LMPD ID
LMP007091
Gene ID
852289
Species
Saccharomyces cerevisiae S288c (Yeast (S288c))
Gene Name
Gpi18p
Gene Symbol
GPI18
Synonyms
-
Alternate Names
Gpi18p
Chromosome
II
EC Number
2.4.1.-

Proteins

Gpi18p
Refseq ID NP_009558
Protein GI 330443421
UniProt ID P38211
mRNA ID NM_001178352
Length 433
RefSeq Status PROVISIONAL
MIVGLTLYFVLFRSIQYLLVFLTPIRQFDTSTSLLLNELCSSPSEINSYWNKYFWNKLLSWDSVFFIKNITSKNGKPQFEHEYAFSQLWTFFVRLFIKSNNDSIYHALRVGVAIENVLFYLSGIVLYFLTKKIFSQNIRQSQFARTIAKKTSLLFFLTSAAGFLTSIYSEPLSFFFAFVGIWSRECSISVPVLGQFDISWRYWFPYSFISMACFTLASLNRSNCVLLGIYFIFDLIELTKNRKFVKAICFPLLSGSLMFSALLYQQYYLPYKTFCPQRGEWCKSQLFSSIFITKTSLYSYIQSHYWGVGLLKYWTPNNIPNFLFAVPNIIILIYSSIYFSKIYPSYNLKALVWITRALVVIVCFFAHVQILNRIASFLPLHLWYLADRLVKTSDPKKMENPKGDDKIVKFYIYWLAFWIPLQTILFAAFLPPA

Gene Information

Entrez Gene ID
852289
Gene Name
Gpi18p
Gene Symbol
GPI18
Species
Saccharomyces cerevisiae S288c

Gene Ontology (GO Annotations)

GO ID Source Type Description
GO:0005783 IDA:SGD C endoplasmic reticulum
GO:0030176 IDA:SGD C integral component of endoplasmic reticulum membrane
GO:0031501 IGI:SGD C mannosyltransferase complex
GO:0004584 IMP:SGD F dolichyl-phosphate-mannose-glycolipid alpha-mannosyltransferase activity
GO:0000030 IMP:SGD F mannosyltransferase activity
GO:0006506 IMP:SGD P GPI anchor biosynthetic process
GO:0097502 IMP:GOC P mannosylation

KEGG Pathway Links

KEGG Pathway ID Description
sce_M00065 GPI-anchor biosynthesis, core oligosaccharide
ko00563 Glycosylphosphatidylinositol(GPI)-anchor biosynthesis
sce00563 Glycosylphosphatidylinositol(GPI)-anchor biosynthesis
sce01100 Metabolic pathways

Domain Information

InterPro Annotations

Accession Description
IPR007315 GPI_Mannosyltransferase_2

UniProt Annotations

Entry Information

Gene Name
Gpi18p
Protein Entry
GPI18_YEAST
UniProt ID
P38211
Species
Yeast (S288c)

Comments

Comment Type Description
Function Mannosyltransferase involved in glycosylphosphatidylinositol-anchor biosynthesis. Responsible for the transfer of the second mannose to the glycosylphosphatidylinositol during GPI precursor assembly. {ECO:0000269|PubMed:15623507, ECO:0000269|PubMed:15720390, ECO:0000269|PubMed:17615295}.
Interaction P36156:ECM4; NbExp=1; IntAct=EBI-21377, EBI-2042717; P40540:KRE27; NbExp=1; IntAct=EBI-21377, EBI-24977; P38800:YHR080C; NbExp=1; IntAct=EBI-21377, EBI-24597;
Pathway Glycolipid biosynthesis; glycosylphosphatidylinositol- anchor biosynthesis.
Similarity Belongs to the PIGV family. {ECO:0000305}.
Subcellular Location Endoplasmic reticulum membrane {ECO:0000269|PubMed:17615295}; Multi-pass membrane protein {ECO:0000269|PubMed:17615295}.
Subunit Part of the GPI mannosyltransferase 2 complex composed of GPI18 and PGA1.

Identical and Related Proteins

Unique RefSeq proteins for LMP007091 (as displayed in Record Overview)

Protein GI Database Accession Length Protein Name
330443421 RefSeq NP_009558 433 Gpi18p

Identical Sequences to LMP007091 proteins

Reference Database Accession Length Protein Name
GI:330443421 SwissProt P38211.2 433 RecName: Full=GPI mannosyltransferase 2; AltName: Full=GPI mannosyltransferase II; Short=GPI-MT-II; AltName: Full=Glycosylphosphatidylinositol-anchor biosynthesis protein 18 [Saccharomyces cerevisiae S288c]
GI:330443421 Third Party Genbank DAA07125.2 433 TPA: Gpi18p [Saccharomyces cerevisiae S288c]

Related Sequences to LMP007091 proteins

Reference Database Accession Length Protein Name
GI:330443421 DBBJ GAA21555.1 433 K7_Gpi18p [Saccharomyces cerevisiae Kyokai no. 7]
GI:330443421 EMBL CAA84940.1 433 unnamed protein product [Saccharomyces cerevisiae]
GI:330443421 GenBank EDV12089.1 433 mannosyltransferase [Saccharomyces cerevisiae RM11-1a]
GI:330443421 GenBank EEU08138.1 433 Gpi18p [Saccharomyces cerevisiae JAY291]
GI:330443421 GenBank EIW11930.1 433 Gpi18p [Saccharomyces cerevisiae CEN.PK113-7D]
GI:330443421 gnl McCuskerlabDuke 433 Gpi18p [Saccharomyces cerevisiae YJM993]