Gene/Proteome Database (LMPD)
Proteins
| Pga1p | |
|---|---|
| Refseq ID | NP_014241 |
| Protein GI | 6324171 |
| UniProt ID | P53896 |
| mRNA ID | NM_001182996 |
| Length | 198 |
| RefSeq Status | PROVISIONAL |
| MVRPQNVHWFIATIVFFIGFVHANTESILYKVPHNFPLKKPRDSSTYARDVNLISSISLSGEAMSQITIEANTTDLELHNTTYIELADLQRDETYQIKVCWSAIHPISINNLQTITIPRFTEFQGTKSDYARILVTFQVLSDSYPSEHAMVPIQVSLITTRLGIPVDIYPTLIVMVLLVAGLVVTRAPHVLNDLLLKF | |
Gene Information
Gene Ontology (GO Annotations)
| GO ID | Source | Type | Description |
|---|---|---|---|
| GO:0030176 | IDA:SGD | C | integral component of endoplasmic reticulum membrane |
| GO:0031501 | IGI:SGD | C | mannosyltransferase complex |
| GO:0000030 | IMP:SGD | F | mannosyltransferase activity |
| GO:0006506 | IMP:SGD | P | GPI anchor biosynthetic process |
| GO:0097502 | IMP:GOC | P | mannosylation |
Domain Information
InterPro Annotations
| Accession | Description |
|---|---|
| IPR019433 | GPI-Mannosyltransferase II co-activator, Pga1 |
UniProt Annotations
Entry Information
Comments
| Comment Type | Description |
|---|---|
| Function | Essential component of the GPI mannosyltransferase 2 complex. Responsible for the transfer of the second mannose to the glycosylphosphatidylinositol during GPI precursor assembly. {ECO:0000269|PubMed:17615295}. |
| Miscellaneous | Present with 6940 molecules/cell in log phase SD medium. {ECO:0000269|PubMed:14562106}. |
| Pathway | Glycolipid biosynthesis; glycosylphosphatidylinositol- anchor biosynthesis. |
| Subcellular Location | Endoplasmic reticulum membrane {ECO:0000269|PubMed:14562095, ECO:0000269|PubMed:17615295}; Single-pass membrane protein {ECO:0000269|PubMed:14562095, ECO:0000269|PubMed:17615295}. |
| Subunit | Part of the GPI mannosyltransferase 2 complex composed of GPI18 and PGA1. |
Identical and Related Proteins
Unique RefSeq proteins for LMP007112 (as displayed in Record Overview)
Identical Sequences to LMP007112 proteins
| Reference | Database | Accession | Length | Protein Name |
|---|---|---|---|---|
| GI:6324171 | GenBank | EIW07936.1 | 198 | Pga1p [Saccharomyces cerevisiae CEN.PK113-7D] |
| GI:6324171 | GenBank | EWG83690.1 | 198 | Pga1p [Saccharomyces cerevisiae R008] |
| GI:6324171 | GenBank | EWG89094.1 | 198 | Pga1p [Saccharomyces cerevisiae P301] |
| GI:6324171 | GenBank | EWG93754.1 | 198 | Pga1p [Saccharomyces cerevisiae R103] |
| GI:6324171 | GenBank | EWH16443.1 | 198 | Pga1p [Saccharomyces cerevisiae P283] |
| GI:6324171 | gnl | McCuskerlabDuke | 198 | Pga1p [Saccharomyces cerevisiae YJM993] |
Related Sequences to LMP007112 proteins
| Reference | Database | Accession | Length | Protein Name |
|---|---|---|---|---|
| GI:6324171 | EMBL | CAR29305.1 | 184 | ZYRO0G05544p [Zygosaccharomyces rouxii] |
| GI:6324171 | GenBank | EGA60805.1 | 204 | Pga1p [Saccharomyces cerevisiae FostersO] |
| GI:6324171 | GenBank | EGA77201.1 | 193 | Pga1p [Saccharomyces cerevisiae Vin13] |
| GI:6324171 | GenBank | EGA81134.1 | 193 | Pga1p [Saccharomyces cerevisiae Lalvin QA23] |
| GI:6324171 | GenBank | EHN00632.1 | 198 | Pga1p [Saccharomyces cerevisiae x Saccharomyces kudriavzevii VIN7] |
| GI:6324171 | GenBank | EJT42225.1 | 200 | PGA1-like protein [Saccharomyces kudriavzevii IFO 1802] |