Gene/Proteome Database (LMPD)

LMPD ID
LMP007125
Gene ID
852857
Species
Saccharomyces cerevisiae S288c (Yeast (S288c))
Gene Name
Cwh41p
Gene Symbol
CWH41
Synonyms
DER7; GLS1
Alternate Names
Cwh41p
Chromosome
VII
EC Number
3.2.1.106

Proteins

Cwh41p
Refseq ID NP_011488
Protein GI 6321411
UniProt ID P53008
mRNA ID NM_001180892
Length 833
RefSeq Status PROVISIONAL
MLISKSKMFKTFWILTSIVLLASATVDISKLQEFEEYQKFTNESLLWAPYRSNCYFGMRPRYVHESPLIMGIMWFNSLSQDGLHSLRHFATPQDKLQKYGWEVYDPRIGGKEVFIDEKNNLNLTVYFVKSKNGENWSVRVQGEPLDPKRPSTASVVLYFSQNGGEIDGKSSLAMIGHDGPNDMKFFGYSKELGEYHLTVKDNFGHYFKNPEYETMEVAPGSDCSKTSHLSLQIPDKEVWKARDVFQSLVSDSIRDILEKEETKQRPADLIPSVLTIRNLYNFNPGNFHYIQKTFDLTKKDGFQFDITYNKLGTTQSISTREQVTELITWSLNEINARFDKQFSFGEGPDSIESVEVKRRFALETLSNLLGGIGYFYGNQLIDRETEFDESQFTEIKLLNAKEEGPFELFTSVPSRGFFPRGFYWDEGFHLLQIMEYDFDLAFEILASWFEMIEDDSGWIAREIILGNEARSKVPQEFQVQNPNIANPPTLLLAFSEMLSRAIENIGDFNSDSYHQVMFNSRTAKFMTNNLEANPGLLTEYAKKIYPKLLKHYNWFRKSQTGLIDEYEEILEDEGIWDKIHKNEVYRWVGRTFTHCLPSGMDDYPRAQPPDVAELNVDALAWVGVMTRSMKQIAHVLKLTQDEQRYAQIEQEVVENLDLLHWSENDNCYCDISIDPEDDEIREFVCHEGYVSVLPFALKLIPKNSPKLEKVVALMSDPEKIFSDYGLLSLSRQDDYFGKDENYWRGPIWMNINYLCLDAMRYYYPEVILDVAGEASNAKKLYQSLKINLSNNIYKVWEEQGYCYENYSPIDGHGTGAEHFTGWTALVVNILGRF

Gene Information

Entrez Gene ID
852857
Gene Name
Cwh41p
Gene Symbol
CWH41
Species
Saccharomyces cerevisiae S288c

Gene Ontology (GO Annotations)

GO ID Source Type Description
GO:0005789 IDA:SGD C endoplasmic reticulum membrane
GO:0016021 IEA:UniProtKB-KW C integral component of membrane
GO:0004573 IDA:SGD F mannosyl-oligosaccharide glucosidase activity
GO:0009272 IMP:SGD P fungal-type cell wall biogenesis
GO:0009311 IEA:InterPro P oligosaccharide metabolic process
GO:0006487 IMP:SGD P protein N-linked glycosylation

KEGG Pathway Links

KEGG Pathway ID Description
sce00510 N-Glycan biosynthesis
sce_M00073 N-glycan precursor trimming
ko04141 Protein processing in endoplasmic reticulum
sce04141 Protein processing in endoplasmic reticulum

Domain Information

InterPro Annotations

Accession Description
IPR004888 Glycoside hydrolase, family 63
IPR008928 Six-hairpin glycosidase-like

UniProt Annotations

Entry Information

Gene Name
Cwh41p
Protein Entry
CWH41_YEAST
UniProt ID
P53008
Species
Yeast (S288c)

Comments

Comment Type Description
Catalytic Activity Exohydrolysis of the non-reducing terminal glucose residues in the mannosyl-oligosaccharide Glc(3)Man(9)GlcNAc(2).
Function Cleaves the distal alpha 1,2-linked glucose residue from the Glc(3)Man(9)GlcNAc(2) oligosaccharide precursor highly specifically. Seems to play a role in beta-1,6-glucan synthesis.
Interaction P53090:ARO8; NbExp=1; IntAct=EBI-5323, EBI-2042933; Q6Q5K6:HUG1; NbExp=1; IntAct=EBI-5323, EBI-392766; P21524:RNR1; NbExp=1; IntAct=EBI-5323, EBI-15234;
Miscellaneous Present with 2840 molecules/cell in log phase SD medium. {ECO:0000269|PubMed:14562106}.
Pathway Glycan metabolism; N-glycan degradation.
Similarity Belongs to the glycosyl hydrolase 63 family. {ECO:0000305}.
Subcellular Location Endoplasmic reticulum membrane; Single-pass type II membrane protein.

Identical and Related Proteins

Unique RefSeq proteins for LMP007125 (as displayed in Record Overview)

Protein GI Database Accession Length Protein Name
6321411 RefSeq NP_011488 833 Cwh41p

Identical Sequences to LMP007125 proteins

Reference Database Accession Length Protein Name
GI:6321411 EMBL CAA96728.1 833 CWH41 [Saccharomyces cerevisiae]
GI:6321411 GenBank AAC49157.1 833 Cwh41p [Saccharomyces cerevisiae]
GI:6321411 GenBank EIW10326.1 833 Cwh41p [Saccharomyces cerevisiae CEN.PK113-7D]
GI:6321411 SwissProt P53008.1 833 RecName: Full=Mannosyl-oligosaccharide glucosidase; AltName: Full=Processing A-glucosidase I; Short=Glucosidase I [Saccharomyces cerevisiae S288c]
GI:6321411 Third Party Genbank DAA08072.1 833 TPA: Cwh41p [Saccharomyces cerevisiae S288c]

Related Sequences to LMP007125 proteins

Reference Database Accession Length Protein Name
GI:6321411 GenBank EDV10261.1 833 glucosidase I [Saccharomyces cerevisiae RM11-1a]
GI:6321411 GenBank EDZ72161.1 833 YGL027Cp-like protein [Saccharomyces cerevisiae AWRI1631]
GI:6321411 GenBank EWG90970.1 833 Cwh41p [Saccharomyces cerevisiae P301]
GI:6321411 GenBank EWG96073.1 833 Cwh41p [Saccharomyces cerevisiae R103]
GI:6321411 GenBank EWH18250.1 833 Cwh41p [Saccharomyces cerevisiae P283]
GI:6321411 gnl McCuskerlabDuke 833 Cwh41p [Saccharomyces cerevisiae YJM993]